Spin Infrequently Occurs in Abstracts of Systematic Reviews For The Pharmacological Treatment of Type 2 Diabetes Mellitus.

health care delivery insulin therapy metformin oral therapies

Journal

Diabetic medicine : a journal of the British Diabetic Association
ISSN: 1464-5491
Titre abrégé: Diabet Med
Pays: England
ID NLM: 8500858

Informations de publication

Date de publication:
21 Jul 2021
Historique:
entrez: 21 7 2021
pubmed: 22 7 2021
medline: 22 7 2021
Statut: aheadofprint

Résumé

Currently, there is a growing body of research demonstrating that spin - the misinterpretation and distortion of a study's findings - is common in different fields of medicine. To our knowledge, no study has investigated its presence in systematic reviews focused on diabetic therapies. We performed a cross-sectional study by searching MEDLINE and Embase for systematic reviews focused on pharmacologic treatments for type 2 diabetes mellitus. Our search retrieved 26,490 records, from which 199 studies were extracted in a masked, duplicate fashion. Each study was evaluated for the nine most severe types of spin and other study design parameters. Spin was presented as frequencies and odds ratios to identify associations between study characteristics. Spin was identified in the abstracts of 15 systematic reviews (15/199, 7.5%). Spin type 5 was the most common type identified (7/199, 3.5%). Spin types 1, 2, 4, and 8 were not identified. In the last 5 years (2016-2021), 7 systematic reviews contained spin within their abstract. There was no association between spins presence and any extracted study characteristic . Our findings show that spin infrequently occurs in abstracts of systematic reviews focused on pharmacologic therapies for type 2 diabetes mellitus. However, any amount of spin can lead to the distortion of a reader's interpretation of the study's findings. Thus, we provide recommendations with rationale to prevent spin in future systematic reviews.

Identifiants

pubmed: 34289158
doi: 10.1111/dme.14653
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e14653

Informations de copyright

This article is protected by copyright. All rights reserved.

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Auteurs

Ryan Ottwell (R)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Department of Internal Medicine, University of Oklahoma, School of Community Medicine, Tulsa, OK, USA.
Samuel J. Wood Library & C.V. Starr Biomedical Information Center, Weill Cornell Medical College, New York, NY, USA.

Lindy Esmond (L)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

William Rea (W)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Kansas City University of Medicine and Biosciences, Joplin, MO, USA.

Micah Hartwell (M)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Mousumi Som (M)

Department of Internal Medicine, Oklahoma State University Medical Center, Tulsa, OK, USA.

Rachael Harris (R)

Department of Internal Medicine, Oklahoma State University Medical Center, Tulsa, OK, USA.

Zhuqi Miao (Z)

Spears School of Business, Oklahoma State University, Stillwater, OK, USA.

Lan Zhu (L)

Department of Statistics, Oklahoma State University, Stillwater, OK, USA.

Wade Arthur (W)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Travis Brachtenbach (T)

Department of Internal Medicine, Oklahoma State University Medical Center, Tulsa, OK, USA.

Drew N Wright (DN)

Spears School of Business, Oklahoma State University, Stillwater, OK, USA.

Matt Vassar (M)

Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Classifications MeSH