Evidence for a Specific Association Between Sustained Attention and Gait Speed in Middle-to-Older-Aged Adults.

cognition cognitive aging executive function gait speed sustained attention

Journal

Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824

Informations de publication

Date de publication:
2021
Historique:
received: 30 04 2021
accepted: 26 05 2021
entrez: 22 7 2021
pubmed: 23 7 2021
medline: 23 7 2021
Statut: epublish

Résumé

Although cognitive decline has previously been associated with mobility limitations and frailty, the relationship between sustained attention and gait speed is incompletely characterized. To better quantify the specificity of the sustained attention and gait speed association, we examined the extent to which this relationship is unique rather than accounted for by executive functioning and physical health characteristics. 58 middle-to-older-aged community-dwelling adults without overt evidence of cognitive impairment (45-90 years old; 21 females) participated in the study. Each participant completed a 4-meter gait speed assessment and validated neuropsychological tests to examine various domains of executive functioning including working memory (i.e., Digit Span), inhibitory control (i.e., D-KEFS Color-Word Interference), and task switching (i.e., D-KEFS Number/Letter Switching). Multiple physical and vascular risk factors were also evaluated. Sustained attention was assessed using the gradual onset continuous performance task (gradCPT), a well-validated go/no-go sustained attention task. A series of linear regression models were used to examine how different aspects of cognition, including sustained attention and traditional measures of executive functioning, related to gait speed while controlling for a variety of physical and vascular risk factors. Among all predictors, gradCPT accuracy explained the most variance in gait speed (

Identifiants

pubmed: 34290601
doi: 10.3389/fnagi.2021.703434
pmc: PMC8289388
doi:

Types de publication

Journal Article

Langues

eng

Pagination

703434

Subventions

Organisme : NIA NIH HHS
ID : K01 AG064044
Pays : United States

Informations de copyright

Copyright © 2021 Park, Aul, DeGutis, Lo, Poole, McGlinchey, Bean, Leritz and Esterman.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Hannah Park (H)

Boston Attention and Learning Laboratory (BALLAB), VA Boston Healthcare System, Boston, MA, United States.
Department of Psychology, Brandeis University, Waltham, MA, United States.

Courtney Aul (C)

Boston Attention and Learning Laboratory (BALLAB), VA Boston Healthcare System, Boston, MA, United States.
National Center for PTSD, VA Boston Healthcare System, Boston, MA, United States.

Joseph DeGutis (J)

Boston Attention and Learning Laboratory (BALLAB), VA Boston Healthcare System, Boston, MA, United States.
Translational Research Center for TBI and Stress Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States.
Department of Psychiatry, Harvard Medical School, Boston, MA, United States.

On-Yee Lo (OY)

Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, United States.
Division of Gerontology, Beth Israel Deaconess Medical Center, Boston, MA, United States.
Department of Medicine, Harvard Medical School, Boston, MA, United States.

Victoria N Poole (VN)

Rush Alzheimer's Disease Center and Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, United States.

Regina McGlinchey (R)

Translational Research Center for TBI and Stress Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States.
Department of Psychiatry, Harvard Medical School, Boston, MA, United States.
New England Geriatric Research, Educational and Clinical Center (NEGRECC), VA Boston Healthcare System, Boston, MA, United States.

Jonathan F Bean (JF)

New England Geriatric Research, Educational and Clinical Center (NEGRECC), VA Boston Healthcare System, Boston, MA, United States.
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA, United States.
Spaulding Rehabilitation Hospital, Boston, MA, United States.

Elizabeth Leritz (E)

Translational Research Center for TBI and Stress Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States.
Department of Psychiatry, Harvard Medical School, Boston, MA, United States.
New England Geriatric Research, Educational and Clinical Center (NEGRECC), VA Boston Healthcare System, Boston, MA, United States.

Michael Esterman (M)

Boston Attention and Learning Laboratory (BALLAB), VA Boston Healthcare System, Boston, MA, United States.
National Center for PTSD, VA Boston Healthcare System, Boston, MA, United States.
Translational Research Center for TBI and Stress Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States.
Department of Psychiatry, Boston University School of Medicine, Boston, MA, United States.

Classifications MeSH