Clinical characteristics and management of olecranon and prepatellar septic bursitis in a multicentre study.


Journal

The Journal of antimicrobial chemotherapy
ISSN: 1460-2091
Titre abrégé: J Antimicrob Chemother
Pays: England
ID NLM: 7513617

Informations de publication

Date de publication:
11 10 2021
Historique:
received: 01 03 2021
accepted: 01 07 2021
pubmed: 23 7 2021
medline: 15 12 2021
entrez: 22 7 2021
Statut: ppublish

Résumé

No current guidelines are available for managing septic bursitis (SB). To describe the clinical characteristics and management of olecranon and prepatellar SB in five French tertiary care centres. This is a retrospective observational multicentre study. SB was diagnosed on the basis of positive cultures of bursal aspirate. In the absence of positive bursal fluid, the diagnosis came from typical clinical presentation, exclusion of other causes of bursitis and favourable response to antibiotic therapy. We included 272 patients (median age of 53 years, 85.3% male and 22.8% with at least one comorbidity). A microorganism was identified in 184 patients (67.6%), from bursal fluids in all but 4. We identified staphylococci in 135 samples (73.4%), streptococci in 35 (19%) and 10 (5.5%) were polymicrobial, while 43/223 bursal samples remained sterile (19.3%). Forty-nine patients (18%) were managed without bursal fluid analysis. Antibiotic treatment was initially administered IV in 41% and this route was preferred in case of fever (P = 0.003) or extensive cellulitis (P = 0.002). Seventy-one (26%) patients were treated surgically. A low failure rate was observed (n = 16/272, 5.9%) and failures were more frequent when the antibiotic therapy lasted <14 days (P = 0.02) in both surgically and medically treated patients. Despite variable treatments, SB resolved in the majority of cases even when the treatment was exclusively medical. The success rate was equivalent in the non-surgical and the surgical management groups. However, a treatment duration of <14 days may require special attention in both groups.

Sections du résumé

BACKGROUND
No current guidelines are available for managing septic bursitis (SB).
OBJECTIVES
To describe the clinical characteristics and management of olecranon and prepatellar SB in five French tertiary care centres.
METHODS
This is a retrospective observational multicentre study. SB was diagnosed on the basis of positive cultures of bursal aspirate. In the absence of positive bursal fluid, the diagnosis came from typical clinical presentation, exclusion of other causes of bursitis and favourable response to antibiotic therapy.
RESULTS
We included 272 patients (median age of 53 years, 85.3% male and 22.8% with at least one comorbidity). A microorganism was identified in 184 patients (67.6%), from bursal fluids in all but 4. We identified staphylococci in 135 samples (73.4%), streptococci in 35 (19%) and 10 (5.5%) were polymicrobial, while 43/223 bursal samples remained sterile (19.3%). Forty-nine patients (18%) were managed without bursal fluid analysis. Antibiotic treatment was initially administered IV in 41% and this route was preferred in case of fever (P = 0.003) or extensive cellulitis (P = 0.002). Seventy-one (26%) patients were treated surgically. A low failure rate was observed (n = 16/272, 5.9%) and failures were more frequent when the antibiotic therapy lasted <14 days (P = 0.02) in both surgically and medically treated patients.
CONCLUSIONS
Despite variable treatments, SB resolved in the majority of cases even when the treatment was exclusively medical. The success rate was equivalent in the non-surgical and the surgical management groups. However, a treatment duration of <14 days may require special attention in both groups.

Identifiants

pubmed: 34293150
pii: 6325488
doi: 10.1093/jac/dkab265
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Multicenter Study Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3029-3032

Commentaires et corrections

Type : CommentIn

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Auteurs

Laurie Charret (L)

Rheumatology Department, CHU Nantes, Nantes, France.
Rheumatology Department, CHD Vendée, La Roche-Sur-Yon, France.

Géraldine Bart (G)

Rheumatology Department, CHU Rennes, Rennes, France.
Centre de référence en infections ostéoarticulaires complexes du Grand Ouest (CRIOGO), CHU de Rennes, 35043, Rennes cedex, France.

Emmanuel Hoppe (E)

Rheumatology Department, CHU Angers, Angers, France.

Emmanuelle Dernis (E)

Rheumatology Department, CH Le Mans, Le Mans, France.

Grégoire Cormier (G)

Rheumatology Department, CHD Vendée, La Roche-Sur-Yon, France.

David Boutoille (D)

Centre de référence en infections ostéoarticulaires complexes du Grand Ouest (CRIOGO), CHU de Rennes, 35043, Rennes cedex, France.
Department of Infectious Diseases, CHU Nantes, Nantes, France.
Centre d'Investigation Clinique, Unité d'Investigation Clinique 1413 INSERM, CHU Nantes, Nantes, France.

Benoit Le Goff (B)

Rheumatology Department, CHU Nantes, Nantes, France.

Christelle Darrieutort-Laffite (C)

Rheumatology Department, CHU Nantes, Nantes, France.

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