'EngNT' - Engineering live neural tissue for nerve replacement.
advanced therapy
neuroregeneration
regenerative medicine
tissue engineering
Journal
Emerging topics in life sciences
ISSN: 2397-8554
Titre abrégé: Emerg Top Life Sci
Pays: England
ID NLM: 101706399
Informations de publication
Date de publication:
12 11 2021
12 11 2021
Historique:
received:
03
06
2021
revised:
06
07
2021
accepted:
13
07
2021
pubmed:
24
7
2021
medline:
15
3
2022
entrez:
23
7
2021
Statut:
ppublish
Résumé
Peripheral nerve injury can result in severe long-term disability and current clinical approaches for repairing large gaps rely on the nerve autograft. Engineered Neural Tissue (EngNT) has been developed to provide living aligned therapeutic cells in a stabilised collagen hydrogel, mimicking the key features of the autograft. This Perspective article will introduce the field and discuss the current stage of translation, highlighting the key opportunities for commercial and clinical development.
Identifiants
pubmed: 34297065
pii: 229311
doi: 10.1042/ETLS20210085
pmc: PMC8726050
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
699-703Informations de copyright
© 2021 The Author(s).
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