Primary congenital glaucoma surgery: outcomes and visual function.


Journal

International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 10 03 2021
accepted: 11 07 2021
pubmed: 24 7 2021
medline: 27 10 2021
entrez: 23 7 2021
Statut: ppublish

Résumé

To assess the long-term visual outcomes of children with PCG, irrespective of the type of surgical procedure, and to create visual acuity curves to help in predicting the development of visual function in these patients. The secondary aim is to identify associated factors for visual decline or loss, highlighting differences between neonatal and infantile subgroups. The medical records of pediatric glaucoma patients from 1996 to 2017 at the University Hospital of Verona (Verona, Italy) were retrospectively reviewed. Visual acuities, surgeries, PCG subtype and etiology of vision impairment were recorded. Statistical analyses were performed to detect factors associated with vision decline. Sixty-seven eyes (40 patients) were included in the study. Developmental predictive curves of visual acuity showed that children with infantile PCG had a better visual outcome than children with neonatal PCG at each step of follow-up. A good-to-moderate VA (< 1 LogMAR) was achieved in 56 eyes (83.6%), while 11 eyes (16.4%) had poor VA (≥ 1 LogMAR). The age at onset, sex, number of surgeries, intraocular pressure (IOP) control (with or without antiglaucoma drugs), axial length (AL) and corneal opacities were statistically associated with vision impairment (p < 0.01). The main cause of visual impairment was amblyopia. Visual outcomes of PCG significantly correlate with the age at diagnosis. Although a good long-term IOP control can often be achieved in PCG, often the visual acuity remains below the lower limits of the normal range. Poor vision in childhood is related to global developmental problems, and referral to third-level services should not be delayed to prevent vision impairment. In this regard, visual acuity curves can be a useful tool for the consultant ophthalmologist to define the visual development of children affected by PCG.

Identifiants

pubmed: 34297306
doi: 10.1007/s10792-021-01957-0
pii: 10.1007/s10792-021-01957-0
pmc: PMC8536551
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3861-3867

Informations de copyright

© 2021. The Author(s).

Références

Clinics (Sao Paulo). 2009;64(6):543-51
pubmed: 19578658
Am J Ophthalmol. 2019 Apr;200:95-99
pubmed: 30639365
J AAPOS. 2012 Aug;16(4):376-81
pubmed: 22929453
Ophthalmology. 2018 Jan;125(1):P105-P142
pubmed: 29108744
Ophthalmology. 2015 Nov;122(11):2216-22
pubmed: 26315044
Eur J Ophthalmol. 2016 Nov 4;26(6):581-587
pubmed: 27033964
Am J Ophthalmol. 2015 Apr;159(4):788-96
pubmed: 25634533
Ophthalmol Glaucoma. 2020 Mar - Apr;3(2):145-157
pubmed: 32672598
J AAPOS. 2011 Apr;15(2):148-52
pubmed: 21596293
Arch Ophthalmol. 2009 Nov;127(11):1436-41
pubmed: 19901208
Clinics (Sao Paulo). 2009;64(8):725-30
pubmed: 19690654
Acta Ophthalmol. 2015 May;93(3):269-75
pubmed: 25307129
Curr Opin Ophthalmol. 2018 Sep;29(5):385-394
pubmed: 30096087
Ophthalmology. 2017 Jul;124(7):1048-1055
pubmed: 28385300
Eur J Ophthalmol. 2017 Nov 8;27(6):705-710
pubmed: 28430330
Ophthalmologica. 1980;181(2):61-73
pubmed: 7219964
Dev Ophthalmol. 1989;16:76-115
pubmed: 2676634
Hum Genet. 1982;61(3):193-7
pubmed: 7173860
Br J Ophthalmol. 2020 Sep;104(9):1288-1292
pubmed: 31871047
J AAPOS. 2002 Jun;6(3):182-6
pubmed: 12075295
Ophthalmic Paediatr Genet. 1990 Mar;11(1):35-40
pubmed: 2348980
Eye (Lond). 2007 Jun;21(6):764-74
pubmed: 16575414
Am J Ophthalmol. 2017 Nov;183:17-24
pubmed: 28860043
Ophthalmology. 2003 Oct;110(10):1909-15
pubmed: 14522762
Saudi J Ophthalmol. 2019 Oct-Dec;33(4):382-388
pubmed: 31920449
Curr Opin Ophthalmol. 2006 Apr;17(2):132-7
pubmed: 16552247
Arch Soc Esp Oftalmol (Engl Ed). 2019 Mar;94(3):119-124
pubmed: 30446240
Ophthalmology. 2018 Jan;125(1):P184-P227
pubmed: 29108745
J AAPOS. 2000 Aug;4(4):205-10
pubmed: 10951295
Graefes Arch Clin Exp Ophthalmol. 2007 Feb;245(2):195-203
pubmed: 16983524
Br J Ophthalmol. 2020 Jul;104(7):967-973
pubmed: 31586948

Auteurs

Elena Gusson (E)

Department of Neuroscience, Biomedicine and Movement Sciences, University Of Verona, Eye Clinic, P.le L.A. Scuro 10, 37134, Verona, Italy.

Francesca Chemello (F)

Department of Neuroscience, Biomedicine and Movement Sciences, University Of Verona, Eye Clinic, P.le L.A. Scuro 10, 37134, Verona, Italy.

Rosa Longo (R)

Department of Neuroscience, Biomedicine and Movement Sciences, University Of Verona, Eye Clinic, P.le L.A. Scuro 10, 37134, Verona, Italy. rosalongo3@gmail.com.

Elia Franzolin (E)

Department of Neuroscience, Biomedicine and Movement Sciences, University Of Verona, Eye Clinic, P.le L.A. Scuro 10, 37134, Verona, Italy.

Roberta Vesentini (R)

Department of Diagnostic and Public Health, University Of Verona, Verona, Italy.

Giuseppe Verlato (G)

Department of Diagnostic and Public Health, University Of Verona, Verona, Italy.

Giorgio Marchini (G)

Department of Neuroscience, Biomedicine and Movement Sciences, University Of Verona, Eye Clinic, P.le L.A. Scuro 10, 37134, Verona, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH