How to Obtain a Mega-Intestine with Normal Morphology: In Silico Modelling of Postnatal Intestinal Growth in a Cd97-Transgenic Mouse.
Areg
Cd97
Klf4
contact inhibition of growth
crypt fission
crypt formation
fate decision
individual cell-based model
mega-intestine
postnatal development
stem cell fate
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
08 Jul 2021
08 Jul 2021
Historique:
received:
01
06
2021
revised:
29
06
2021
accepted:
02
07
2021
entrez:
24
7
2021
pubmed:
25
7
2021
medline:
5
8
2021
Statut:
epublish
Résumé
Intestinal cylindrical growth peaks in mice a few weeks after birth, simultaneously with crypt fission activity. It nearly stops after weaning and cannot be reactivated later. Transgenic mice expressing
Identifiants
pubmed: 34298973
pii: ijms22147345
doi: 10.3390/ijms22147345
pmc: PMC8305140
pii:
doi:
Substances chimiques
Adgre5 protein, mouse
0
Klf4 protein, mouse
0
Kruppel-Like Factor 4
0
Receptors, G-Protein-Coupled
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Bundesministerium für Bildung und Forschung
ID : 031A312
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