SARS-CoV-2 Antibody Serology Testing in a 3-Month-Old Organ Donor: A Case Report and Review of Available Literature.


Journal

Transplantation proceedings
ISSN: 1873-2623
Titre abrégé: Transplant Proc
Pays: United States
ID NLM: 0243532

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 15 06 2021
accepted: 27 06 2021
pubmed: 25 7 2021
medline: 29 10 2021
entrez: 24 7 2021
Statut: ppublish

Résumé

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a highly prevalent infectious disease. Currently, organs are not being transplanted from donors who are SARS-CoV-2 positive. It remains unclear as to how to differentiate active from recovered patients. We report our recent experience of a 3-month-old deceased organ donor who died as the result of an anoxic brain injury after a cardiopulmonary arrest (presumed sudden infant death syndrome). The child was born to a mother presumed to have coronavirus disease 2019. The donor tested negative for SARS-CoV-2 reverse transcriptase-polymerase chain reaction and positive for SARS-CoV-2 immunoglobulin A antibodies. We suspect this is the first known report of its kind and noteworthy for the organ donation and transplantation community.

Identifiants

pubmed: 34301402
pii: S0041-1345(21)00451-6
doi: 10.1016/j.transproceed.2021.06.028
pmc: PMC8249701
pii:
doi:

Substances chimiques

Antibodies, Viral 0

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2435-2437

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Susan Nelson (S)

LifeGift, Fort Worth, Texas. Electronic address: snelson@lifegift.org.

Christopher C Curran (CC)

LifeGift, Fort Worth, Texas.

David L Sutcliffe (DL)

Children's Health Dallas, Dallas, Texas.

George Rofaiel (G)

Division of Abdominal Transplantation and Advance Hepatobiliary Surgery, Department of Surgery, University of Utah, Salt Lake City, Utah.

Yeh-Chung Chang (YC)

Department of Pediatrics, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina.

Larry Easterling (L)

LifeGift, Fort Worth, Texas.

R Patrick Wood (RP)

LifeGift, Fort Worth, Texas.

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Classifications MeSH