Adherence to index-based dietary patterns in childhood and BMI trajectory during the transition to adolescence: the EPOCH study.


Journal

International journal of obesity (2005)
ISSN: 1476-5497
Titre abrégé: Int J Obes (Lond)
Pays: England
ID NLM: 101256108

Informations de publication

Date de publication:
11 2021
Historique:
received: 23 01 2020
accepted: 19 07 2021
revised: 10 07 2021
pubmed: 26 7 2021
medline: 2 2 2022
entrez: 25 7 2021
Statut: ppublish

Résumé

In the United States, one in five adolescents are obese. Index-based dietary patterns are measures of the overall diet that have the potential to serve as valuable obesity risk stratification tools. However, little is known about the association between adherence to index-based dietary patterns in childhood and BMI during the transition from childhood to adolescence. To prospectively examine the relationship between adherence to three index-based dietary patterns in childhood and BMI trajectory during the transition to adolescence. The study included 581 children enrolled in a Colorado prospective cohort study conducted between 2006 and 2015. Dietary intake was assessed with the Block Kids Food Frequency Questionnaire at age 10 years. Scores were calculated for the Healthy Eating Index-2010 (HEI-2010), the alternate Mediterranean (aMED) diet, and the Dietary Approaches to Stop Hypertension (DASH) diet. Weight and height were assessed via anthropometry at two research visits (ages 10 and 16 years), with interim clinical measurements extracted from Kaiser Permanente medical records. Separate mixed models were used to assess the association between each diet index score and BMI over a 6-year period. Models were stratified by sex and adjusted for age, race/ethnicity, income, and exposure to gestational diabetes. Median (IQR) number of BMI assessments was 14 (10-18). Among girls, for every ten-unit increase in HEI-2010 score, there was an average 0.64 kg/m Efforts to prevent adolescent obesity could benefit from considering the degree of adherence to federal dietary guidance, as assessed by the HEI, in the period preceding adolescence, especially among girls.

Sections du résumé

BACKGROUND
In the United States, one in five adolescents are obese. Index-based dietary patterns are measures of the overall diet that have the potential to serve as valuable obesity risk stratification tools. However, little is known about the association between adherence to index-based dietary patterns in childhood and BMI during the transition from childhood to adolescence.
OBJECTIVE
To prospectively examine the relationship between adherence to three index-based dietary patterns in childhood and BMI trajectory during the transition to adolescence.
METHODS
The study included 581 children enrolled in a Colorado prospective cohort study conducted between 2006 and 2015. Dietary intake was assessed with the Block Kids Food Frequency Questionnaire at age 10 years. Scores were calculated for the Healthy Eating Index-2010 (HEI-2010), the alternate Mediterranean (aMED) diet, and the Dietary Approaches to Stop Hypertension (DASH) diet. Weight and height were assessed via anthropometry at two research visits (ages 10 and 16 years), with interim clinical measurements extracted from Kaiser Permanente medical records. Separate mixed models were used to assess the association between each diet index score and BMI over a 6-year period. Models were stratified by sex and adjusted for age, race/ethnicity, income, and exposure to gestational diabetes.
RESULTS
Median (IQR) number of BMI assessments was 14 (10-18). Among girls, for every ten-unit increase in HEI-2010 score, there was an average 0.64 kg/m
CONCLUSIONS
Efforts to prevent adolescent obesity could benefit from considering the degree of adherence to federal dietary guidance, as assessed by the HEI, in the period preceding adolescence, especially among girls.

Identifiants

pubmed: 34304241
doi: 10.1038/s41366-021-00917-z
pii: 10.1038/s41366-021-00917-z
pmc: PMC8542564
mid: NIHMS1726111
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

2439-2446

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK068001
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM121081
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK007658
Pays : United States

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature Limited.

Références

Ogden CL, Carroll MD, Lawman HG, Fryar CD, Kruszon-Moran D, Kit BK, et al. Trends in obesity prevalence among children and adolescents in the United States, 1988–1994 through 2013–2014. JAMA. 2016;315:2292–9.
pubmed: 27272581 pmcid: 6361521 doi: 10.1001/jama.2016.6361
Quek YH, Tam WWS, Zhang MWB, Ho RCM. Exploring the association between childhood and adolescent obesity and depression: a meta-analysis. Obes Rev. 2017;18:742–54.
pubmed: 28401646 doi: 10.1111/obr.12535
Griffiths LJ, Parsons TJ, Hill AJ. Self-esteem and quality of life in obese children and adolescents: a systematic review. Int J Pediatr Obes. 2010;5:282–304.
pubmed: 20210677 doi: 10.3109/17477160903473697
Buttitta M, Iliescu C, Rousseau A, Guerrien A. Quality of life in overweight and obese children and adolescents: a literature review. Qual Life Res. 2014;23:1117–39.
pubmed: 24249217 doi: 10.1007/s11136-013-0568-5
Gooding HC, Milliren C, Shay CM, Richmond TK, Field AE, Gillman MW. Achieving cardiovascular health in young adulthood-which adolescent factors matter? J Adolesc Health. 2016;58:119–21.
pubmed: 26707234 pmcid: 4874326 doi: 10.1016/j.jadohealth.2015.09.011
Dai S, Labarthe DR, Grunbaum JA, Harrist RB, Mueller WH. Longitudinal analysis of changes in indices of obesity from age 8 years to age 18 years. Project HeartBeat! Am J Epidemiol. 2002;156:720–9.
pubmed: 12370160 doi: 10.1093/aje/kwf109
Dietz WH. Critical periods in childhood for the development of obesity. Am J Clin Nutr. 1994;59:955–9.
pubmed: 8172099 doi: 10.1093/ajcn/59.5.955
Peneau S, Giudici KV, Gusto G, Goxe D, Lantieri O, Hercberg S, et al. Growth trajectories of body mass index during childhood: associated factors and health outcome at adulthood. J Pediatr. 2017;186:64–71.e1.
pubmed: 28283258 doi: 10.1016/j.jpeds.2017.02.010
Aris IM, Rifas-Shiman SL, Li LJ, Kleinman KP, Coull BA, Gold DR, et al. Patterns of body mass index milestones in early life and cardiometabolic risk in early adolescence. Int J Epidemiol. 2019;48:157–67.
pubmed: 30624710 pmcid: 6380298 doi: 10.1093/ije/dyy286
Hu FB. Dietary pattern analysis: a new direction in nutritional epidemiology. Curr Opin Lipidol. 2002;13:3–9.
pubmed: 11790957 doi: 10.1097/00041433-200202000-00002
Hodge A, Bassett J. What can we learn from dietary pattern analysis? Public Health Nutr. 2016;19:191–4.
pubmed: 26784585 doi: 10.1017/S1368980015003730
Reedy J, Krebs-Smith SM, Miller PE, Liese AD, Kahle LL, Park Y, et al. Higher diet quality is associated with decreased risk of all-cause, cardiovascular disease, and cancer mortality among older adults. J Nutr. 2014;144:881–9.
pubmed: 24572039 pmcid: 4018951 doi: 10.3945/jn.113.189407
Harrington S. The role of sugar-sweetened beverage consumption in adolescent obesity: a review of the literature. J Sch Nurs. 2008;24:3–12.
pubmed: 18220450 doi: 10.1177/10598405080240010201
Wall CR, Stewart AW, Hancox RJ, Murphy R, Braithwaite I, Beasley R, et al. Association between frequency of consumption of fruit, vegetables, nuts and pulses and BMI: analyses of the International Study of Asthma and Allergies in Childhood (ISAAC). Nutrients. 2018;10:316. https://doi.org/10.3390/nu10030316 .
An R. Diet quality and physical activity in relation to childhood obesity. Int J Adolesc Med Health. 2017;29. https://doi.org/10.1515/ijamh-2015-0045 .
Mohseni-Takalloo S, Hosseini-Esfahani F, Mirmiran P, Azizi F. Associations of pre-defined dietary patterns with obesity associated phenotypes in tehranian adolescents. Nutrients. 2016;8:505. https://doi.org/10.3390/nu8080505 .
Cagiran Yilmaz F, Cagiran D, Ozcelik AO. Adolescent obesity and its association with diet quality and cardiovascular risk factors. Ecol Food Nutr. 2019;58:207–18.
pubmed: 30786756 doi: 10.1080/03670244.2019.1580581
Baird J, Jacob C, Barker M, Fall CH, Hanson M, Harvey NC, et al. Developmental origins of health and disease: a lifecourse approach to the prevention of non-communicable diseases. Healthcare. 2017;5:14. https://doi.org/10.3390/healthcare5010014 .
Asghari G, Mirmiran P, Yuzbashian E, Azizi F. A systematic review of diet quality indices in relation to obesity. Br J Nutr. 2017;117:1055–65.
pubmed: 28478768 doi: 10.1017/S0007114517000915
Drenowatz C, Shook RP, Hand GA, Hebert JR, Blair SN. The independent association between diet quality and body composition. Sci Rep. 2014;4:4928.
pubmed: 24816165 pmcid: 4894392 doi: 10.1038/srep04928
Jones-Smith JC, Neufeld LM, Laraia B, Ramakrishnan U, Garcia-Guerra A, Fernald LC. Early life growth trajectories and future risk for overweight. Nutr Diabetes. 2013;3:e60.
pubmed: 23381665 pmcid: 3584986 doi: 10.1038/nutd.2012.32
Biro FM, Kiess W. Contemporary trends in onset and completion of puberty, gain in height and adiposity. Endocr Dev. 2016;29:122–33.
pubmed: 26680575 doi: 10.1159/000438881
Cullen KW, Watson K, Zakeri I. Relative reliability and validity of the Block Kids Questionnaire among youth aged 10 to 17 years. J Am Diet Assoc. 2008;108:862–6.
pubmed: 18442512 doi: 10.1016/j.jada.2008.02.015
Guenther PM, Kirkpatrick SI, Reedy J, Krebs-Smith SM, Buckman DW, Dodd KW, et al. The Healthy Eating Index-2010 is a valid and reliable measure of diet quality according to the 2010 Dietary Guidelines for Americans. J Nutr. 2014;144:399–407.
pubmed: 24453128 pmcid: 3927552 doi: 10.3945/jn.113.183079
Fung TT, McCullough ML, Newby PK, Manson JE, Meigs JB, Rifai N, et al. Diet-quality scores and plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr. 2005;82:163–73.
pubmed: 16002815 doi: 10.1093/ajcn/82.1.163
Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med. 1997;336:1117–24.
pubmed: 9099655 doi: 10.1056/NEJM199704173361601
Dinu M, Pagliai G, Casini A, Sofi F. Mediterranean diet and multiple health outcomes: an umbrella review of meta-analyses of observational studies and randomised trials. Eur J Clin Nutr. 2018;72:30–43.
pubmed: 28488692 doi: 10.1038/ejcn.2017.58
Hu FB. The Mediterranean diet and mortality-olive oil and beyond. N Engl J Med. 2003;348:2595–6.
pubmed: 12826632 doi: 10.1056/NEJMp030069
Trichopoulou A, Kouris-Blazos A, Wahlqvist ML, Gnardellis C, Lagiou P, Polychronopoulos E, et al. Diet and overall survival in elderly people. BMJ. 1995;311:1457–60.
pubmed: 8520331 pmcid: 2543726 doi: 10.1136/bmj.311.7018.1457
Sacks FM, Svetkey LP, Vollmer WM, Appel LJ, Bray GA, Harsha D, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med. 2001;344:3–10.
pubmed: 11136953 doi: 10.1056/NEJM200101043440101
Fung TT, Chiuve SE, McCullough ML, Rexrode KM, Logroscino G, Hu FB. Adherence to a DASH-style diet and risk of coronary heart disease and stroke in women. Arch Intern Med. 2008;168:713–20.
pubmed: 18413553 doi: 10.1001/archinte.168.7.713
Hockett CW, Harrall KK, Moore BF, Starling AP, Bellatorre A, Sauder KA, et al. Persistent effects of in utero overnutrition on offspring adiposity: the Exploring Perinatal Outcomes among Children (EPOCH) study. Diabetologia. 2019;62:2017–24.
pubmed: 31444527 pmcid: 7593989 doi: 10.1007/s00125-019-04981-z
Altman DG, Royston P. The cost of dichotomising continuous variables. BMJ. 2006;332:1080.
pubmed: 16675816 pmcid: 1458573 doi: 10.1136/bmj.332.7549.1080
Durao C, Oliveira A, Santos AC, Severo M, Guerra A, Barros H, et al. Protein intake and dietary glycemic load of 4-year-olds and association with adiposity and serum insulin at 7 years of age: sex-nutrient and nutrient-nutrient interactions. Int J Obes. 2017;41:533–41.
doi: 10.1038/ijo.2016.240
Durao C, Severo M, Oliveira A, Moreira P, Guerra A, Barros H, et al. Association between dietary patterns and adiposity from 4 to 7 years of age. Public Health Nutr. 2017;20:1973–82.
pubmed: 28534458 doi: 10.1017/S1368980017000854
Wisniewski AB, Chernausek SD. Gender in childhood obesity: family environment, hormones, and genes. Gend Med. 2009;6:76–85.
pubmed: 19318220 doi: 10.1016/j.genm.2008.12.001
Laird NM, Ware JH. Random-effects models for longitudinal data. Biometrics. 1982;38:963–74.
pubmed: 7168798 doi: 10.2307/2529876
Crume TL, Ogden L, Daniels S, Hamman RF, Norris JM, Dabelea D. The impact of in utero exposure to diabetes on childhood body mass index growth trajectories: the EPOCH study. J Pediatr. 2011;158:941–6.
pubmed: 21238981 pmcid: 3090715 doi: 10.1016/j.jpeds.2010.12.007
Kenward MG, Roger JH. Small sample inference for fixed effects from restricted maximum likelihood. Biometrics. 1997;53:983–97.
pubmed: 9333350 doi: 10.2307/2533558
Peckins MK, Negriff S, Schneiderman JU, Gordis EB, Susman EJ. The moderating role of cortisol reactivity on the link between maltreatment and body mass index trajectory across adolescence. J Adolesc Health. 2019;65:239–47.
pubmed: 31043344 pmcid: 6650365 doi: 10.1016/j.jadohealth.2019.02.017
Zhang T, Whelton PK, Xi B, Krousel-Wood M, Bazzano L, He J, et al. Rate of change in body mass index at different ages during childhood and adult obesity risk. Pediatr Obes. 2019;14:e12513.
pubmed: 30702812 pmcid: 6684349 doi: 10.1111/ijpo.12513
Min J, Wen X, Xue H, Wang Y. Ethnic disparities in childhood BMI trajectories and obesity and potential causes among 29,250 US children: findings from the early childhood longitudinal study-birth and kindergarten cohorts. Int J Obes. 2018;42:1661–70.
doi: 10.1038/s41366-018-0091-4
Thomson JL, Tussing-Humphreys LM, Goodman MH, Landry AS. Diet quality in a nationally representative sample of American children by sociodemographic characteristics. Am J Clin Nutr. 2019;109:127–38.
pubmed: 30596813 doi: 10.1093/ajcn/nqy284
Cohen JFW, Lehnerd ME, Houser RF, Rimm EB. Dietary approaches to stop hypertension diet, weight status, and blood pressure among children and adolescents: National Health and Nutrition Examination Surveys 2003–2012. J Acad Nutr Diet. 2017;117:1437–44.e2.
pubmed: 28539258 doi: 10.1016/j.jand.2017.03.026
Martin-Calvo N, Chavarro JE, Falbe J, Hu FB, Field AE. Adherence to the Mediterranean dietary pattern and BMI change among US adolescents. Int J Obes. 2016;40:1103–8.
doi: 10.1038/ijo.2016.59
DeSalvo KB, Olson R, Casavale KO. Dietary guidelines for Americans. JAMA. 2016;315:457–8.
pubmed: 26746707 doi: 10.1001/jama.2015.18396
Psaltopoulou T, Tzanninis S, Ntanasis-Stathopoulos I, Panotopoulos G, Kostopoulou M, Tzanninis IG, et al. Prevention and treatment of childhood and adolescent obesity: a systematic review of meta-analyses. World J Pediatr. 2019;15:350–81.
pubmed: 31313240 doi: 10.1007/s12519-019-00266-y
Oellingrath IM, Svendsen MV, Brantsaeter AL. Tracking of eating patterns and overweight—a follow-up study of Norwegian schoolchildren from middle childhood to early adolescence. Nutr J. 2011;10:106.
pubmed: 21978299 pmcid: 3200168 doi: 10.1186/1475-2891-10-106
Cutler GJ, Flood A, Hannan P, Neumark-Sztainer D. Major patterns of dietary intake in adolescents and their stability over time. J Nutr. 2009;139:323–8.
pubmed: 19091799 doi: 10.3945/jn.108.090928
Ambrosini GL, Emmett PM, Northstone K, Jebb SA. Tracking a dietary pattern associated with increased adiposity in childhood and adolescence. Obesity. 2014;22:458–65.
pubmed: 23804590 doi: 10.1002/oby.20542
Mikkilä V, Räsänen L, Raitakari OT, Marniemi J, Pietinen P, Rönnemaa T, et al. Major dietary patterns and cardiovascular risk factors from childhood to adulthood. The Cardiovascular Risk in Young Finns Study. Br J Nutr. 2007;98:218–25.
pubmed: 17367571 doi: 10.1017/S0007114507691831
Langford R, Bonell C, Jones H, Pouliou T, Murphy S, Waters E, et al. The World Health Organization’s Health Promoting Schools framework: a Cochrane systematic review and meta-analysis. BMC Public Health. 2015;15:130.
pubmed: 25886385 pmcid: 4339015 doi: 10.1186/s12889-015-1360-y
Luckner H, Moss JR, Gericke CA. Effectiveness of interventions to promote healthy weight in general populations of children and adults: a meta-analysis. Eur J Public Health. 2012;22:491–7.
pubmed: 21967748 doi: 10.1093/eurpub/ckr141
Gortmaker SL, Long MW, Resch SC, Ward ZJ, Cradock AL, Barrett JL, et al. Cost effectiveness of childhood obesity interventions: evidence and methods for CHOICES. Am J Prev Med. 2015;49:102–11.
pubmed: 26094231 doi: 10.1016/j.amepre.2015.03.032
Khalil CB, Johnson-Down L, Egeland GM. Emerging obesity and dietary habits among James Bay Cree youth. Public Health Nutr. 2010;13:1829–37.
pubmed: 20392310 doi: 10.1017/S1368980010000406
Piercy KL, Troiano RP, Ballard RM, Carlson SA, Fulton JE, Galuska DA, et al. The physical activity guidelines for Americans. JAMA. 2018;320:2020–8.
pubmed: 30418471 doi: 10.1001/jama.2018.14854
Bekelman TA, Sauder KA, Rockette-Wagner B, Glueck DH, Dabelea D. Sociodemographic predictors of adherence to national diet and physical activity guidelines at age 5 years: the Healthy Start Study. Am J Health Promot. 2021;35:514–24.
Lee H, Kang M, Song WO, Shim JE, Paik HY. Gender analysis in the development and validation of FFQ: a systematic review. Br J Nutr. 2016;115:666–71.
pubmed: 26652249 doi: 10.1017/S0007114515004717
Yoshida Y, Scribner R, Chen L, Broyles S, Phillippi S, Tseng TS. Diet quality and its relationship with central obesity among Mexican Americans: findings from National Health and Nutrition Examination Survey (NHANES) 1999–2012. Public Health Nutr. 2017;20:1193–202.
pubmed: 27974064 doi: 10.1017/S1368980016003190
Sacks FM, Obarzanek E, Windhauser MM, Svetkey LP, Vollmer WM, McCullough M, et al. Rationale and design of the Dietary Approaches to Stop Hypertension trial (DASH). A multicenter controlled-feeding study of dietary patterns to lower blood pressure. Ann Epidemiol. 1995;5:108–18.
pubmed: 7795829 doi: 10.1016/1047-2797(94)00055-X
Golpour-Hamedani S, Mohammadifard N, Khosravi A, Feizi A, Safavi SM. Dietary approaches to stop hypertension diet and obesity: a cross-sectional study of Iranian children and adolescents. ARYA Atheroscler. 2017;13:7–13.
pubmed: 28761449 pmcid: 5515185
Berz JP, Singer MR, Guo X, Daniels SR, Moore LL. Use of a DASH food group score to predict excess weight gain in adolescent girls in the National Growth and Health Study. Arch Pediatr Adolesc Med. 2011;165:540–6.
pubmed: 21646587 doi: 10.1001/archpediatrics.2011.71
Metcalf BS, Hosking J, Jeffery AN, Voss LD, Henley W, Wilkin TJ. Fatness leads to inactivity, but inactivity does not lead to fatness: a longitudinal study in children (EarlyBird 45). Arch Dis Child. 2011;96:942–7.
pubmed: 20573741 doi: 10.1136/adc.2009.175927
Ambrosini GL, Huang RC, Mori TA, Hands BP, O’Sullivan TA, de Klerk NH, et al. Dietary patterns and markers for the metabolic syndrome in Australian adolescents. Nutr Metab Cardiovasc Dis. 2010;20:274–83.
pubmed: 19748245 doi: 10.1016/j.numecd.2009.03.024
Mesirow MS, Welsh JA. Changing beverage consumption patterns have resulted in fewer liquid calories in the diets of US children: National Health and Nutrition Examination Survey 2001–2010. J Acad Nutr Diet. 2015;115:559–66.e4.
pubmed: 25441966 doi: 10.1016/j.jand.2014.09.004
Maier JH, Barry R. Associations among physical activity, diet, and obesity measures change during adolescence. J Nutr Metab. 2015;2015:805065.
pubmed: 26539299 pmcid: 4619959 doi: 10.1155/2015/805065
Chaparro MP, Koupil I, Byberg L. Maternal pre-pregnancy BMI and offspring body composition in young adulthood: the modifying role of offspring sex and birth order. Public Health Nutr. 2017;20:3084–9.
pubmed: 28851474 doi: 10.1017/S1368980017002191
Donnelly JE, Smith BK. Is exercise effective for weight loss with ad libitum diet? Energy balance, compensation, and gender differences. Exerc Sport Sci Rev. 2005;33:169–74.
pubmed: 16239833 doi: 10.1097/00003677-200510000-00004

Auteurs

Traci A Bekelman (TA)

Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, Aurora, CO, USA. Traci.Bekelman@cuanschutz.edu.
Department of Epidemiology, Colorado School of Public Health, Aurora, CO, USA. Traci.Bekelman@cuanschutz.edu.

Brandy M Ringham (BM)

Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, Aurora, CO, USA.

Katherine A Sauder (KA)

Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, Aurora, CO, USA.
Department of Epidemiology, Colorado School of Public Health, Aurora, CO, USA.
Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Susan L Johnson (SL)

Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Kylie H Harrall (KH)

Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, Aurora, CO, USA.

Deborah H Glueck (DH)

Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, Aurora, CO, USA.
Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Dana Dabelea (D)

Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, Colorado School of Public Health, Aurora, CO, USA.
Department of Epidemiology, Colorado School of Public Health, Aurora, CO, USA.
Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

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