Improvements in strength and agility measures of functional fitness following a telehealth-delivered home-based exercise intervention in endometrial cancer survivors.
Intervention
Quality of life
Resistance exercise
Strength
Journal
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
ISSN: 1433-7339
Titre abrégé: Support Care Cancer
Pays: Germany
ID NLM: 9302957
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
22
01
2021
accepted:
04
07
2021
pubmed:
26
7
2021
medline:
15
12
2021
entrez:
25
7
2021
Statut:
ppublish
Résumé
Endometrial cancer is strongly linked to obesity and inactivity; however, increased physical activity has important benefits even in the absence of weight loss. Resistance (strength) training can deliver these benefits; yet few women participate in resistance exercise. The purpose of this study was to describe both physiological and functional changes following a home-based strength training intervention. Forty post-treatment endometrial cancer survivors within 5 years of diagnosis were enrolled in a pilot randomized trial, comparing twice-weekly home-based strength exercise to wait list control. Participants conducted the exercises twice per week for 10 supervised weeks with 5 weeks of follow-up. Measures included DXA-measured lean mass, functional fitness assessments, blood biomarkers, and quality of life outcomes. On average, participants were 60.9 years old (SD = 8.7) with BMI of 39.9 kg/m Home-based muscle-strengthening exercise led to favorable and clinically relevant improvements in 3 of 7 physical function assessments. Physical function, body composition, blood biomarkers, and patient-reported outcomes were feasible to measure. These fitness improvements were observed over a relatively short time frame of 10 weeks.
Identifiants
pubmed: 34304292
doi: 10.1007/s00520-021-06415-2
pii: 10.1007/s00520-021-06415-2
pmc: PMC9362897
mid: NIHMS1827736
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
447-455Subventions
Organisme : NCI NIH HHS
ID : P30 CA014520
Pays : United States
Organisme : NCI NIH HHS
ID : R03 CA230965
Pays : United States
Organisme : Division of Cancer Epidemiology and Genetics, National Cancer Institute
ID : 1R03CA230965-01A1
Organisme : University of Wisconsin Carbone Cancer Center
ID : 2P30CA014520-44
Organisme : NCATS NIH HHS
ID : UL1 TR002373
Pays : United States
Organisme : American Cancer Society
ID : IRG-15-213-51
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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