A pH-eQTL Interaction at the

Parkinson’s disease RIT2 SYT4 eQTL analysis gene expression pH rs12456492 substantia nigra (SN)

Journal

Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824

Informations de publication

Date de publication:
2021
Historique:
received: 03 04 2021
accepted: 14 06 2021
entrez: 26 7 2021
pubmed: 27 7 2021
medline: 27 7 2021
Statut: epublish

Résumé

Parkinson's disease causes severe motor and cognitive disabilities that result from the progressive loss of dopamine neurons in the substantia nigra. The rs12456492 variant in the

Identifiants

pubmed: 34305570
doi: 10.3389/fnagi.2021.690632
pmc: PMC8299340
doi:

Types de publication

Journal Article

Langues

eng

Pagination

690632

Informations de copyright

Copyright © 2021 Patel, Howard and French.

Déclaration de conflit d'intérêts

LF owns shares in and has received consulting fees from Cortexyme Inc., a company that is developing gingipain inhibitors to treat neurodegenerative diseases. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Sejal Patel (S)

Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Derek Howard (D)

Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.

Leon French (L)

Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Institute for Medical Science, University of Toronto, Toronto, ON, Canada.

Classifications MeSH