Acute Physiological Effects of Continuous Versus Intermittent Walking During Golf in Individuals With Knee Osteoarthritis: A Pilot Study.
Journal
American journal of physical medicine & rehabilitation
ISSN: 1537-7385
Titre abrégé: Am J Phys Med Rehabil
Pays: United States
ID NLM: 8803677
Informations de publication
Date de publication:
01 05 2022
01 05 2022
Historique:
pubmed:
27
7
2021
medline:
23
4
2022
entrez:
26
7
2021
Statut:
ppublish
Résumé
The aim of the study was to compare the acute effects of walking the golf course versus using a golf cart during a round of golf on biological markers of joint disease, joint pain, and cardiovascular parameters in individuals with knee osteoarthritis. Participants with knee OA (n = 10) older than 50 yrs were recruited for this crossover designed study in which they completed two 18-hole rounds of golf: (1) walking the course and (2) using a golf cart. Five control participants (n = 5) performed the walking condition only. Step count, heart rate, rating of perceived exertion and pain using the Numeric Pain Rating Scale were measured during the round. Serum was collected at baseline, 9th hole (halfway), and 18th hole (completion) and tested for biomarkers associated with tissue turnover (cartilage oligomeric matrix protein), inflammation (tumor necrosis factor α, interleukin 1β, interleukin 6), and degradative enzyme production (matrix metalloproteinase 3, matrix metalloproteinase 13). In knee OA participants, walking the course was associated with significantly higher step count and duration of moderate/vigorous physical activity (72.2% vs. 32.6% of the round) but did lead to a significant increase in knee joint pain (P < 0.05). Both conditions caused cartilage oligomeric matrix protein and matrix metalloproteinase 13 concentration increases from baseline to completion (P < 0.05), but inflammatory markers (tumor necrosis factor α, interleukin 6, and interleukin 1β, P < 0.05) only increased when walking the course. Biomarker concentrations did not increase in control participants. Walking the course optimizes the duration of moderate/vigorous activity during a round of golf, but the golf cart is a beneficial option in those with exacerbated joint pain and inflammation that would otherwise limit participation.
Identifiants
pubmed: 34310345
doi: 10.1097/PHM.0000000000001855
pii: 00002060-202205000-00009
pmc: PMC8783928
mid: NIHMS1726115
doi:
Substances chimiques
Biomarkers
0
Cartilage Oligomeric Matrix Protein
0
Interleukin-1beta
0
Interleukin-6
0
Tumor Necrosis Factor-alpha
0
Matrix Metalloproteinase 13
EC 3.4.24.-
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
460-467Subventions
Organisme : NCATS NIH HHS
ID : KL2 TR001424
Pays : United States
Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Financial disclosure statements have been obtained, and no conflicts of interest have been reported by the authors or by any individuals in control of the content of this article.
Références
Lawrence RC, Felson DT, Helmick CG, et al.: Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum 2008;58:26–35
Lundebjerg N: Exercise prescription for older adults with osteoarthritis pain: consensus practice recommendations. J Am Geriatr Soc 2001;49:808–23
Ettinger WH Jr., Burns R, Messier SP, et al.: A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis. The Fitness Arthritis and Seniors Trial (FAST). JAMA 1997;277:25–31
Rejeski WJ, Brawley LR, Ettinger W, et al.: Compliance to exercise therapy in older participants with knee osteoarthritis: implications for treating disability. Med Sci Sports Exerc 1997;29:977–85
Hendry M, Williams NH, Markland D, et al.: Why should we exercise when our knees hurt? A qualitative study of primary care patients with osteoarthritis of the knee. Fam Pract 2006;23:558–67
Murray AD, Daines L, Archibald D, et al.: The relationships between golf and health: a scoping review. Br J Sports Med 2017;51:12–9
McGwin G Jr., Zoghby JT, Griffin R, et al.: Incidence of golf cart-related injury in the United States. J Trauma 2008;64:1562–6
Andriacchi TP, Mündermann A, Smith RL, et al.: A framework for the in vivo pathomechanics of osteoarthritis at the knee. Ann Biomed Eng 2004;32:447–57
Tseng S, Reddi AH, Di Cesare PE: Cartilage oligomeric matrix protein (COMP): a biomarker of arthritis. Biomark Insights 2009;4:33–44
Saxne T, Heinegård D: Cartilage oligomeric matrix protein: a novel marker of cartilage turnover detectable in synovial fluid and blood. Rheumatology 1992;31:583–91
Singh S, Shahi U, Kumar D, et al.: Serum cartilage oligomeric matrix protein: tool for early diagnosis and grading of severity of primary knee osteoarthritis. Int J Osteol Orthop 2014;1:1–7
Urso ML, Pierce JR, Alemany JA, et al.: Effects of exercise training on the matrix metalloprotease response to acute exercise. Eur J Appl Physiol 2009;106:655–63
Edd SN, Favre J, Blazek K, et al.: Altered gait mechanics and elevated serum pro-inflammatory cytokines in asymptomatic patients with MRI evidence of knee cartilage loss. Osteoarthr Cartil 2017;25:899–906
Neidhart M, Müller-Ladner U, Frey W, et al.: Increased serum levels of non-collagenous matrix proteins (cartilage oligomeric matrix protein and melanoma inhibitory activity) in marathon runners. Osteoarthr Cartil 2000;8:222–9
Kellgren JH, Lawrence JS: Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957;16:494–502
Jayabalan P, Gustafson J, Sowa GA, et al.: A stimulus-response framework to investigate the influence of continuous versus interval walking exercise on select serum biomarkers in knee osteoarthritis. Am J Phys Med Rehabil 2019;98:287–91
Wahl Y, Düking P, Droszez A, et al.: Criterion-validity of commercially available physical activity tracker to estimate step count, covered distance and energy expenditure during sports conditions. Front Physiol 2017;8:725
Broman G, Johnsson L, Kaijser L: Golf: a high intensity interval activity for elderly men. Aging Clin Exp Res 2004;16:375–81
Farrar JT, Young JP Jr., LaMoreaux L, et al.: Clinical importance of changes in chronic pain intensity measured on an 11-point Numerical Pain Rating Scale. Pain 2001;94:149–58
Mündermann A, Dyrby CO, Andriacchi TP, et al.: Serum concentration of cartilage oligomeric matrix protein (COMP) is sensitive to physiological cyclic loading in healthy adults. Osteoarthr Cartil 2005;13:34–8
Erhart-Hledik JC, Favre J, Asay JL, et al.: A relationship between mechanically-induced changes in serum cartilage oligomeric matrix protein (COMP) and changes in cartilage thickness after 5 years. Osteoarthr Cartil 2012;20:1309–15
Kim HJ, Lee YH, Kim CK: Changes in serum cartilage oligomeric matrix protein (COMP), plasma CPK and plasma hs-CRP in relation to running distance in a marathon (42.195 km) and an ultra-marathon (200 km) race. Eur J Appl Physiol 2009;105:765–70
Harkey MS, Luc BA, Golightly YM, et al.: Osteoarthritis-related biomarkers following anterior cruciate ligament injury and reconstruction: a systematic review. Osteoarthr Cartil 2015;23:1–12
Biomarkers Definitions Working Group: Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001;69:89–95
Scott JPR, Sale C, Greeves JP, et al.: Effect of exercise intensity on the cytokine response to an acute bout of running. Med Sci Sports Exerc 2011;43:2297–306
Beckwée D, Vaes P, Cnudde M, et al.: Osteoarthritis of the knee: why does exercise work? A qualitative study of the literature. Ageing Res Rev 2013;12:226–36
Farahmand B, Broman G, De Faire U, et al.: Golf: a game of life and death—reduced mortality in Swedish golf players. Scand J Med Sci Sports 2009;19:419–24
Zunzer SC, von Duvillard SP, Tschakert G, et al.: Energy expenditure and sex differences of golf playing. J Sports Sci 2013;31:1045–53
Gheita TA, El-Awar AH, El-Ansary MM, et al.: Cartilage oligomeric matrix protein (COMP) levels in serum and synovial fluid in osteoarthritis (OA) patients: correlation with clinical, radiological and laboratory parameters. Osteoarthritis Cartil 2015;23(S2):A85
Neidhart M, Hauser N, Paulsson M, et al.: Small fragments of cartilage oligomeric matrix protein in synovial fluid and serum as markers for cartilage degradation. Br J Rheumatol 1997;36:1151–60