Snake venom proteomics and antivenomics of two Sundaic lance-headed pit vipers: Trimeresurus wiroti (Malaysia) and Trimeresurus puniceus (Indonesia).
Craspedocephalus
Green pit viper antivenom
Hemotoxin
Immunorecognition
Venomics
Journal
Comparative biochemistry and physiology. Part D, Genomics & proteomics
ISSN: 1878-0407
Titre abrégé: Comp Biochem Physiol Part D Genomics Proteomics
Pays: Netherlands
ID NLM: 101270611
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
02
05
2021
revised:
28
06
2021
accepted:
28
06
2021
pubmed:
27
7
2021
medline:
15
12
2021
entrez:
26
7
2021
Statut:
ppublish
Résumé
Envenomation by two medically important Sundaic pit vipers, Trimeresurus wiroti (Malaysia) and Trimeresurus puniceus (Indonesia), causes hemotoxic syndrome with a potentially fatal outcome. Research on the compositions and antigenicity of these pit viper venoms is however lacking, limiting our understanding of the pathophysiology and treatment of envenomation. This study investigated the venom proteomes of both species through a protein decomplexation strategy, applying C
Identifiants
pubmed: 34311411
pii: S1744-117X(21)00087-3
doi: 10.1016/j.cbd.2021.100875
pii:
doi:
Substances chimiques
Snake Venoms
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
100875Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.