The Molecular and Nuclear Dynamics of X-Chromosome Inactivation.

Animals Cell Nucleus / metabolism Dosage Compensation, Genetic Female Mammals RNA, Long Noncoding / genetics X Chromosome / genetics X Chromosome Inactivation

Journal

Cold Spring Harbor perspectives in biology
ISSN: 1943-0264
Titre abrégé: Cold Spring Harb Perspect Biol
Pays: United States
ID NLM: 101513680

Informations de publication

Date de publication:
17 05 2022
Historique:
pmc-release: 01 04 2024
pubmed: 28 7 2021
medline: 20 5 2022
entrez: 27 7 2021
Statut: epublish

Résumé

In female eutherian mammals, dosage compensation of X-linked gene expression is achieved during development through transcriptional silencing of one of the two X chromosomes. Following X chromosome inactivation (XCI), the inactive X chromosome remains faithfully silenced throughout somatic cell divisions. XCI is dependent on

Identifiants

DOI: 10.1101/cshperspect.a040196 PMID: 34312245 PMC: PMC9121902
pubmed: 34312245
pii: cshperspect.a040196
doi: 10.1101/cshperspect.a040196
pmc: PMC9121902
pii:
doi:

Substances chimiques

RNA, Long Noncoding 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2022 Cold Spring Harbor Laboratory Press; all rights reserved.

Auteurs

François Dossin (F)

European Molecular Biology Laboratory, Director's Unit, 69117 Heidelberg, Germany.

Edith Heard (E)

European Molecular Biology Laboratory, Director's Unit, 69117 Heidelberg, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The Molecular and Nuclear Dynamics of...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Noyau de la cellule › The Molecular and Nuclear Dynamics of...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Compensation de dosage génétique › The Molecular and Nuclear Dynamics of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › The Molecular and Nuclear Dynamics of...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › ARN long non codant › The Molecular and Nuclear Dynamics of...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Chromosomes › Chromosomes sexuels › Chromosome X › The Molecular and Nuclear Dynamics of...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Compensation de dosage génétique › Inactivation du chromosome X › The Molecular and Nuclear Dynamics of...