A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.


Journal

NAR cancer
ISSN: 2632-8674
Titre abrégé: NAR Cancer
Pays: England
ID NLM: 101769553

Informations de publication

Date de publication:
Jun 2021
Historique:
received: 11 11 2020
revised: 22 04 2021
accepted: 04 05 2021
entrez: 28 7 2021
pubmed: 29 7 2021
medline: 29 7 2021
Statut: epublish

Résumé

The elevated expression of the splicing regulator SRSF10 in metastatic colorectal cancer (CRC) stimulates the production of the pro-tumorigenic

Identifiants

pubmed: 34316707
doi: 10.1093/narcan/zcab019
pii: zcab019
pmc: PMC8210162
doi:

Types de publication

Journal Article

Langues

eng

Pagination

zcab019

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of NAR Cancer.

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Auteurs

Muhammad Sohail (M)

Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Lulzim Shkreta (L)

Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Johanne Toutant (J)

Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Safwat Rabea (S)

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.

Jean-Philippe Babeu (JP)

Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Caroline Huard (C)

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada.

Jasmin Coulombe-Huntington (J)

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada.

Aurélie Delannoy (A)

Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Morgane Placet (M)

Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Sameh Geha (S)

Department of Pathology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.

Fernand-Pierre Gendron (FP)

Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

François Boudreau (F)

Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Mike Tyers (M)

Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada.

David S Grierson (DS)

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada.

Benoit Chabot (B)

Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.

Classifications MeSH