Xanthomas Regression in an 8-Year-Old Boy Treated With Lomitapide.
CVD, cardiovascular disease
HoFH, homozygous familial hypercholesterolemia
LDL-C, low-density lipoprotein cholesterol
LL, lipid-lowering
colesevelam
ezetimibe
homozygous familial hypercholesterolemia
lomitapide
statins
Journal
JACC. Case reports
ISSN: 2666-0849
Titre abrégé: JACC Case Rep
Pays: Netherlands
ID NLM: 101757292
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
18
04
2019
revised:
24
06
2019
accepted:
26
06
2019
entrez:
28
7
2021
pubmed:
4
9
2019
medline:
4
9
2019
Statut:
epublish
Résumé
This case reports on an 8-year-old boy with homozygous familial hypercholesterolemia with large tuberous xanthomas over his hands, elbows, buttocks, knees, and feet. Lomitapide 40 mg daily (steadily increased) was added to his classical lipid-lowering therapy. A 50% reduction in the thickness, hardness, size, and color intensity of xanthomas was reported after 2 years of treatment. (
Identifiants
pubmed: 34316840
doi: 10.1016/j.jaccas.2019.06.029
pii: S2666-0849(19)30243-8
pmc: PMC8288695
doi:
Types de publication
Journal Article
Langues
eng
Pagination
414-416Informations de copyright
© 2019 The Authors.
Références
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pubmed: 30270089
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pubmed: 30948303
Adv Ther. 2019 Jul;36(7):1786-1811
pubmed: 31102204