Immune Checkpoint Inhibitor-Associated Myocarditis: A Run of Bad Luck or Rather Deficient-Monitoring Protocol?
CMR
CMR, cardiac magnetic resonance
ICI, immune checkpoint inhibitor
LGE, late gadolinium enhancement
LV, left ventricular
LVEF, left ventricular ejection fraction
MMF, mycophenolate mofetil
NSCLC, non–small cell lung cancer
PD, programmed death
PD-L, programmed death-ligand
RR, reference range
VT, ventricular tachycardia
irAE
irAE, immune-related adverse event
myocarditis
pembrolizumab
ventricular tachycardia
Journal
JACC. Case reports
ISSN: 2666-0849
Titre abrégé: JACC Case Rep
Pays: Netherlands
ID NLM: 101757292
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
09
10
2019
revised:
23
12
2019
accepted:
26
12
2019
entrez:
28
7
2021
pubmed:
15
4
2020
medline:
15
4
2020
Statut:
epublish
Résumé
Immune checkpoint inhibitors (ICIs) can induce immunity-related adverse events. We demonstrate the clinical use of cardiac magnetic resonance and endomyocardial biopsy in the diagnosis and subsequent monitoring of ICI-associated myocarditis, suggesting the need to establish and evaluate a cardiac monitoring protocol for patients under ICI therapy. (
Identifiants
pubmed: 34317309
doi: 10.1016/j.jaccas.2019.12.047
pii: S2666-0849(20)30146-7
pmc: PMC8298681
doi:
Types de publication
Case Reports
Langues
eng
Pagination
630-635Informations de copyright
© 2020 The Authors.
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