Mogamulizumab-Associated Acute Myocarditis in a Patient With T-Cell Lymphoma.
CCR4, C-X-C chemokine receptor type 4
CHOPE, cyclophosphamide, doxorubicin, vincristine, prednisone, and etoposide
CMR, cardiac magnetic resonance
ECG, electrocardiogram
ICI, checkpoint inhibitor
LGE, late gadolinium enhancement
LVEF, left ventricular ejection fraction
MR sequences
PE, pulmonary embolus
TTE, transthoracic echocardiogram
Treg, T regulatory cells
acute heart failure
cancer
cardiomyopathy
Journal
JACC. Case reports
ISSN: 2666-0849
Titre abrégé: JACC Case Rep
Pays: Netherlands
ID NLM: 101757292
Informations de publication
Date de publication:
07 Jul 2021
07 Jul 2021
Historique:
received:
04
01
2021
revised:
26
03
2021
accepted:
02
04
2021
entrez:
28
7
2021
pubmed:
29
7
2021
medline:
29
7
2021
Statut:
epublish
Résumé
A 62-year-old woman with human T-lymphotropic virus type 1 cell lymphoma developed heart failure after mogamulizumab, an immunotherapy agent. Clinical presentation and cardiac magnetic resonance imaging were consistent with myocarditis, and a recurrence of heart failure occurred after rechallenge with the therapy. (
Identifiants
pubmed: 34317676
doi: 10.1016/j.jaccas.2021.04.001
pii: S2666-0849(21)00320-X
pmc: PMC8311348
doi:
Types de publication
Case Reports
Langues
eng
Pagination
1018-1023Subventions
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
This work was supported by American Heart Association (grant #18CDA34110361; LAB, 2018). The authors have reported that they have no relationships relevant to the contents of this paper to disclose.
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