Antibacterial effectiveness of diluted preparations of intracanal medicaments used in regenerative endodontic treatment on dentin infected by bacterial biofilm: An
Biofilms
Enterococcus faecalis
regenerative endodontics
Journal
Dental research journal
ISSN: 1735-3327
Titre abrégé: Dent Res J (Isfahan)
Pays: Iran
ID NLM: 101471186
Informations de publication
Date de publication:
2021
2021
Historique:
received:
14
10
2019
revised:
03
03
2020
accepted:
03
05
2020
entrez:
29
7
2021
pubmed:
30
7
2021
medline:
30
7
2021
Statut:
epublish
Résumé
Conventional drug mixtures used in regenerative endodontic procedures have a toxic effect and no consensus has been reached about their best composition and concentration. Therefore, the aim of this study was to determine minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum biofilm inhibitory concentration (MBIC) of the antimicrobial preparations and to compare their antimicrobial efficacy on bovine dentin infected by For this original All medicament groups significantly showed an antimicrobial efficacy compared with negative control (without antibiotic) ( TAP, DAP, co-amoxiclav, and CH (at its MBC value) could effectively eliminate biofilm bacteria on the dentin surface. Antimicrobial efficacy of other medicaments containing cefaclor or clindamycin was limited.
Sections du résumé
BACKGROUND
BACKGROUND
Conventional drug mixtures used in regenerative endodontic procedures have a toxic effect and no consensus has been reached about their best composition and concentration. Therefore, the aim of this study was to determine minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum biofilm inhibitory concentration (MBIC) of the antimicrobial preparations and to compare their antimicrobial efficacy on bovine dentin infected by
MATERIALS AND METHODS
METHODS
For this original
RESULTS
RESULTS
All medicament groups significantly showed an antimicrobial efficacy compared with negative control (without antibiotic) (
CONCLUSION
CONCLUSIONS
TAP, DAP, co-amoxiclav, and CH (at its MBC value) could effectively eliminate biofilm bacteria on the dentin surface. Antimicrobial efficacy of other medicaments containing cefaclor or clindamycin was limited.
Types de publication
Journal Article
Langues
eng
Pagination
37Informations de copyright
Copyright: © 2021 Dental Research Journal.
Déclaration de conflit d'intérêts
The authors of this manuscript declare that they have no conflicts of interest, real or perceived, financial, or nonfinancial in this article.
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