Lecithinized superoxide dismutase in the past and in the present: Any role in the actual pandemia of COVID-19?

Animals Antioxidants / pharmacology COVID-19 / diagnosis Humans Multiple Organ Failure / diagnosis Oxidative Stress / drug effects Pandemics Phosphatidylcholines / pharmacology Reactive Oxygen Species / antagonists & inhibitors Superoxide Dismutase / pharmacology COVID-19 Drug Treatment
Antioxidants COVID-19 disease Lecitinized superoxide dismutase Lung infections Oxidative stress Superoxide mimetics

Journal

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
ISSN: 1950-6007
Titre abrégé: Biomed Pharmacother
Pays: France
ID NLM: 8213295

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 01 05 2021
revised: 30 06 2021
accepted: 12 07 2021
pubmed: 30 7 2021
medline: 15 9 2021
entrez: 29 7 2021
Statut: ppublish

Résumé

The Coronavirus disease 19 (Covid-19) pandemic is devastating the public health: it is urgent to find a viable therapy to reduce the multiorgan damage of the disease. A validated therapeutic protocol is still missing. The most severe forms of the disease are related to an exaggerated inflammatory response. The pivotal role of reactive oxygen species (ROS) in the amplification of inflammation makes the antioxidants a potential therapy, but clinical trials are needed. The lecitinized superoxide dismutase (PC-SOD) could represent a possibility because of bioaviability, safety, and its modulatory effect on the innate immune response in reducing the harmful consequences of oxidative stress. In this review we summarize the evidence on lecitinized superoxide dismutase in animal and human studies, to highlight the rationale for using the PC-SOD to treat COVID-19.

Identifiants

DOI: 10.1016/j.biopha.2021.111922 PMID: 34323703 PMC: PMC8277551
pubmed: 34323703
pii: S0753-3322(21)00704-6
doi: 10.1016/j.biopha.2021.111922
pmc: PMC8277551
pii:
doi:

Substances chimiques

Antioxidants 0
Phosphatidylcholines 0
Reactive Oxygen Species 0
Superoxide Dismutase EC 1.15.1.1
lecithinized superoxide dismutase EC 1.15.1.1

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

111922

Informations de copyright

Copyright © 2021. Published by Elsevier Masson SAS.

Références

J Pharmacol Exp Ther. 1994 Dec;271(3):1672-7
pubmed: 7996483
Life Sci. 2001 Jul 13;69(8):935-44
pubmed: 11488406
Oxid Med Cell Longev. 2020 Aug 12;2020:3173281
pubmed: 32855764
J Clin Med. 2020 Jun 19;9(6):
pubmed: 32575380
Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1865-79
pubmed: 16987039
Chest. 2012 Oct;142(4):1011-1019
pubmed: 22459774
Cell Mol Immunol. 2016 Jan;13(1):3-10
pubmed: 26189369
Lancet Respir Med. 2020 May;8(5):475-481
pubmed: 32105632
Eur J Immunol. 2006 Jun;36(6):1364-73
pubmed: 16703568
Surg Neurol. 2003 Mar;59(3):156-60; discussion 160-1
pubmed: 12681536
Adv Exp Med Biol. 2017;967:105-137
pubmed: 29047084
J Biol Chem. 2015 Sep 11;290(37):22805-17
pubmed: 26231211
Chem Biol Interact. 2020 Sep 1;328:109211
pubmed: 32735799
Am J Physiol Lung Cell Mol Physiol. 2010 Mar;298(3):L348-60
pubmed: 20034962
Kidney Int. 2001 Aug;60(2):786-96
pubmed: 11473663
Cell. 2008 Apr 18;133(2):235-49
pubmed: 18423196
Am J Hypertens. 2004 Sep;17(9):852-60
pubmed: 15363831
Inflamm Res. 2006 Sep;55(9):359-63
pubmed: 17122956
Pharmacol Ther. 1990;47(2):219-31
pubmed: 2203071
J Toxicol Sci. 2011;36(6):733-40
pubmed: 22129737
Br J Clin Pharmacol. 2008 Jan;65(1):22-9
pubmed: 17610527
Free Radic Biol Med. 2000 Jul 1;29(1):34-41
pubmed: 10962203
Stroke. 2007 Mar;38(3):1057-62
pubmed: 17272760
Am J Physiol Renal Physiol. 2001 Nov;281(5):F948-57
pubmed: 11592952
Nature. 2013 May 23;497(7450):498-502
pubmed: 23636320
Lancet. 2020 May 2;395(10234):1417-1418
pubmed: 32325026
Ann Hepatol. 2020 Jan - Feb;19(1):92-98
pubmed: 31607646
Oxid Med Cell Longev. 2018 Feb 11;2018:5730395
pubmed: 29599897
Lancet. 2020 Aug 1;396(10247):313-319
pubmed: 32534626
J Clin Pharmacol. 2008 Feb;48(2):184-92
pubmed: 18089770
Mol Biosyst. 2016 Jan;12(1):274-82
pubmed: 26595232
JAMA Intern Med. 2020 Jul 21;:
pubmed: 32692365
J Pharmacol Exp Ther. 2011 Sep;338(3):810-8
pubmed: 21665943
Stroke. 1995 Apr;26(4):627-34; discussion 635
pubmed: 7709410
Oxid Med Cell Longev. 2018 Dec 30;2018:7404082
pubmed: 30693064
Curr Opin Crit Care. 2015 Feb;21(1):82-90
pubmed: 25501020
Transl Res. 2017 Dec;190:61-68
pubmed: 29080401
Life Sci. 2020 Oct 1;258:118166
pubmed: 32739471
Acta Physiol Scand Suppl. 1980;492:19-23
pubmed: 6939305
Respirology. 2010 Nov;15(8):1261-5
pubmed: 20920130
Intensive Care Med. 2020 May;46(5):846-848
pubmed: 32125452
J Burn Care Res. 2009 Mar-Apr;30(2):321-8
pubmed: 19242269
Biomed Pharmacother. 2005 May;59(4):139-42
pubmed: 15862706
J Pharmacol Exp Ther. 1992 Sep;262(3):1214-9
pubmed: 1527725
Int J Mol Sci. 2015 Nov 20;16(11):27770-80
pubmed: 26610475
Respir Care. 2014 Sep;59(9):1422-32
pubmed: 25053831
Am J Respir Crit Care Med. 2000 Apr;161(4 Pt 1):1279-84
pubmed: 10764324
Colorectal Dis. 2008 Nov;10(9):931-4
pubmed: 18294268
Eur Respir J Suppl. 2003 Sep;44:4s-6s
pubmed: 14582891
J Neurotrauma. 2001 Jan;18(1):93-103
pubmed: 11200253
Am J Respir Cell Mol Biol. 2017 Feb;56(2):179-190
pubmed: 27668315
Antioxid Redox Signal. 2020 Jul 10;33(2):59-65
pubmed: 32323565
Am J Physiol Lung Cell Mol Physiol. 2003 Jun;284(6):L917-25
pubmed: 12736188
BMC Pulm Med. 2014 May 17;14:86
pubmed: 24886036
Biochem Biophys Res Commun. 2012 Sep 21;426(2):253-9
pubmed: 22935414
Immunobiology. 2019 Mar;224(2):242-253
pubmed: 30739804
J Free Radic Biol Med. 1985;1(2):103-10
pubmed: 3939137
Int J Clin Pharmacol Ther. 2019 Dec;57(12):596-602
pubmed: 31599225
J Pharmacol Exp Ther. 2009 Jan;328(1):152-64
pubmed: 18927353
Circulation. 1989 May;79(5):1137-42
pubmed: 2653661
Biochim Biophys Acta. 2012 Oct;1818(10):2465-75
pubmed: 22305963
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
Arthritis Rheumatol. 2017 Jun;69(6):1135-1143
pubmed: 28217930
Circulation. 2004 Nov 16;110(20):3252-8
pubmed: 15533864
Nature. 2020 Sep;585(7823):16-17
pubmed: 32860026
Am J Physiol Lung Cell Mol Physiol. 2012 Jun 15;302(12):L1250-61
pubmed: 22505669
Kidney Int. 2002 Mar;61(3):1160-9
pubmed: 11849471
J Pharm Sci. 2014 Jul;103(7):1987-1994
pubmed: 24867597
Viruses. 2018 Jul 26;10(8):
pubmed: 30049972
Lancet. 2020 Mar 28;395(10229):1033-1034
pubmed: 32192578
J Control Release. 2006 Jan 10;110(2):283-289
pubmed: 16332351
Am J Ophthalmol. 2003 May;135(5):613-9
pubmed: 12719067
Radiat Res. 2009 Sep;172(3):331-8
pubmed: 19708782
Genomics Proteomics Bioinformatics. 2019 Jun;17(3):319-331
pubmed: 31494268
Redox Biol. 2015;4:180-3
pubmed: 25588755
Antioxidants (Basel). 2020 Oct 10;9(10):
pubmed: 33050459
Biochem Biophys Res Commun. 2001 Aug 3;285(5):1220-5
pubmed: 11478786
Toxicol Appl Pharmacol. 2004 Jan 15;194(2):180-8
pubmed: 14736498

Auteurs

Ilaria Farella (I)

Neonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and 6 Human Oncology, "Aldo Moro" University of Bari, Policlinico Hospital-Piazza Giulio Cesare n. 11, 70124 Bari, Italy. Electronic address: ilaria.farella@uniba.it.

Raffaella Panza (R)

Neonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and 6 Human Oncology, "Aldo Moro" University of Bari, Policlinico Hospital-Piazza Giulio Cesare n. 11, 70124 Bari, Italy. Electronic address: raffaella.panza@uniba.it.

Manuela Capozza (M)

Neonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and 6 Human Oncology, "Aldo Moro" University of Bari, Policlinico Hospital-Piazza Giulio Cesare n. 11, 70124 Bari, Italy.

Nicola Laforgia (N)

Neonatology and Neonatal Intensive Care Unit, Department of Biomedical Science and 6 Human Oncology, "Aldo Moro" University of Bari, Policlinico Hospital-Piazza Giulio Cesare n. 11, 70124 Bari, Italy.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Antioxydants › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie virale › COVID-19 › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Choc › Défaillance multiviscérale › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Épidémies de maladies › Épidémies › Pandémies › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Lipides › Lipides membranaires › Phospholipides › Glycérophosphate › Acides phosphatidiques › Glycérophospholipides › Phosphatidylcholines › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Espèces réactives de l'oxygène › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Superoxide dismutase › Lecithinized superoxide dismutase in the past...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Traitements médicamenteux de la COVID-19 › Lecithinized superoxide dismutase in the past...