BEAUTY and the breast: is adjuvant chemotherapy the right time for a beauty boost? Lessons learned from a large randomized controlled trial.


Journal

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
ISSN: 1573-2649
Titre abrégé: Qual Life Res
Pays: Netherlands
ID NLM: 9210257

Informations de publication

Date de publication:
Mar 2022
Historique:
accepted: 08 07 2021
pubmed: 30 7 2021
medline: 17 3 2022
entrez: 29 7 2021
Statut: ppublish

Résumé

Beauty care (BTC) is offered at many cancer hospitals having a great uptake among patients. Nevertheless, its benefits in the Quality of life (QoL) of cancer survivors have not been assessed so far. Our study aims to determine whether BTC improves patients' QoL related to their body image measured by the BRBI scale of the QLQ-BR23 questionnaire at the end of adjuvant chemotherapy, after breast cancer (BC) surgery. The BEAUTY study is a prospective, randomized, controlled intervention trial. The following patient-reported outcomes were filled before initiation of chemotherapy (T1) and after their last cycle (T2): EORTC QLQ-C30, QLQ-BR23, and Body Image Scale (BIS). Primary objective was improvement in the BIS of BR23 (BRBI). A qualitative assessment of patients' experience was performed at each cycle through a relevant questionnaire. In total, 269 (67%) patients filled BRBI at T1 and T2. Mean BRBI scores substantially decreased between T1 and T2 and were not different with or without BTC (p = 0.88). Qualitative assessment suggests impact of BTC in physical well-being and avoids thoughts related to the disease. A substantial proportion of patients have a poor body image and chemotherapy induced a substantial degradation of BRBI scores. Although BTC does not seem to impact BRBI scores, the qualitative assessment suggests some benefit of BTC in other domains. Our study highlights the need to assess patients-perceived body image and build tailored interventions at this critical phase of their disease and generates hypothesis for the impact of BTC among BC patients. Clinical trial registration The study is registered at ClinicalTrials.gov under the NCT01459003 number since October 25, 2011.

Identifiants

pubmed: 34324138
doi: 10.1007/s11136-021-02947-6
pii: 10.1007/s11136-021-02947-6
doi:

Banques de données

ClinicalTrials.gov
['NCT01459003']

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

723-732

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

Références

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Auteurs

Mahasti Saghatchian (M)

Medical Oncology Department, Gustave Roussy, Villejuif, France. mahasti.saghatchian@ahparis.org.
Breast Cancer Unit, Institut de Cancérologie Gustave Roussy, 114, rue Edouard Vaillant, 94800, Villejuif, France. mahasti.saghatchian@ahparis.org.

Benjamin Lacas (B)

Biostatistics and Epidemiology Department, Gustave Roussy, Villejuif, France.
INSERM U1018, CESP, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.

Cécile Charles (C)

Social Sciences Research Unit, Gustave Roussy, Villejuif, France.

Amal Ghouadni (A)

Medical Oncology Department, Gustave Roussy, Villejuif, France.

Gabrielle Tergemina Clain (GT)

Biostatistics and Epidemiology Department, Gustave Roussy, Villejuif, France.

Diane Boinon (D)

Social Sciences Research Unit, Gustave Roussy, Villejuif, France.

Suzette Delaloge (S)

Medical Oncology Department, Gustave Roussy, Villejuif, France.

Ines Vaz-Luis (I)

Medical Oncology Department, Gustave Roussy, Villejuif, France.

Sarah Dauchy (S)

Supportive Care Department, Gustave Roussy, Villejuif, France.

Philippe Amiel (P)

Social Sciences Research Unit, Gustave Roussy, Villejuif, France.

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