Photochemical (Hetero-)Arylation of Aryl Sulfonium Salts.
Journal
Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393
Informations de publication
Date de publication:
20 08 2021
20 08 2021
Historique:
pubmed:
31
7
2021
medline:
31
7
2021
entrez:
30
7
2021
Statut:
ppublish
Résumé
The construction of (hetero)biaryls, which are ubiquitous scaffolds among medical substances, functional materials, and agrochemicals, constitutes a key application of cross-coupling methods. However, these usually require multiple synthetic steps. Herein, we report a simple photoinduced and catalyst-free C-H/C-H (hetero)arylation cross-coupling through aryl thianthrenium salts, which are formed site-selectively by direct C-H functionalization. The key to this approach is the UV-light, which can disrupt the C-S bond to form thianthrene radical cations and aryl radicals.
Identifiants
pubmed: 34327991
doi: 10.1021/acs.orglett.1c01904
pmc: PMC8383302
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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