Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021.

B.1.351 SARS-CoV-2 breakthrough infection transmission unvaccinated partner vaccination

Journal

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
ISSN: 1560-7917
Titre abrégé: Euro Surveill
Pays: Sweden
ID NLM: 100887452

Informations de publication

Date de publication:
07 2021
Historique:
entrez: 30 7 2021
pubmed: 31 7 2021
medline: 4 8 2021
Statut: ppublish

Résumé

A breakthrough infection occurred in a fully Comirnaty (BNT162b2) vaccinated healthcare worker with high levels of neutralising antibodies with the SARS-CoV-2 B.1.351 (Beta) variant in February 2021. The infection was subsequently transmitted to their unvaccinated spouse. Sequencing revealed an identical virus in both spouses, with a match of all nine single nucleotide polymorphisms typical for B.1.351. To the best of our knowledge, no transmission of any variant of SARS-CoV-2 from a fully vaccinated person has been described before.

Identifiants

pubmed: 34328074
doi: 10.2807/1560-7917.ES.2021.26.30.2100673
pmc: PMC8323454
doi:

Substances chimiques

COVID-19 Vaccines 0
Vaccines 0
BNT162 Vaccine N38TVC63NU

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Références

BMJ. 2021 Jul 23;374:n1875
pubmed: 34301631
Bioinformatics. 2010 Mar 1;26(5):589-95
pubmed: 20080505
N Engl J Med. 2021 Apr 15;384(15):1412-1423
pubmed: 33626250
Clin Microbiol Infect. 2021 Feb 20;:
pubmed: 33618012
Infection. 2021 Apr 23;:
pubmed: 33891281
Clin Chem Lab Med. 2020 Aug 27;58(12):2121-2130
pubmed: 32853163
Nat Med. 2021 Mar;27(3):440-446
pubmed: 33531709
Genome Biol. 2019 Jan 8;20(1):8
pubmed: 30621750
N Engl J Med. 2021 Jun 23;:
pubmed: 34161702
Lancet. 2021 May 15;397(10287):1819-1829
pubmed: 33964222
N Engl J Med. 2020 Dec 31;383(27):2603-2615
pubmed: 33301246
Nat Microbiol. 2020 Nov;5(11):1403-1407
pubmed: 32669681

Auteurs

Inge Kroidl (I)

Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Germany.
German Center for Infection Research (DZIF), Partner Site, Munich, Germany.

Ingo Mecklenburg (I)

Klinikum Landsberg am Lech, Internal Medicine, Landsberg am Lech, Germany.

Peter Schneiderat (P)

Klinikum Landsberg am Lech, Internal Medicine, Landsberg am Lech, Germany.

Katharina Müller (K)

German Center for Infection Research (DZIF), Partner Site, Munich, Germany.
Bundeswehr Institute of Microbiology, 80937 Munich, Germany.

Philipp Girl (P)

German Center for Infection Research (DZIF), Partner Site, Munich, Germany.
Bundeswehr Institute of Microbiology, 80937 Munich, Germany.

Roman Wölfel (R)

German Center for Infection Research (DZIF), Partner Site, Munich, Germany.
Bundeswehr Institute of Microbiology, 80937 Munich, Germany.

Andreas Sing (A)

Bavarian Health and Food Safety Authority (LGL), Oberschleissheim, Germany.

Alexandra Dangel (A)

Bavarian Health and Food Safety Authority (LGL), Oberschleissheim, Germany.

Andreas Wieser (A)

Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Germany.
German Center for Infection Research (DZIF), Partner Site, Munich, Germany.

Michael Hoelscher (M)

Division of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität (LMU) Munich, Germany.
German Center for Infection Research (DZIF), Partner Site, Munich, Germany.

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Classifications MeSH