Nickel-Catalyzed Deaminative Cyanation: Nitriles and One-Carbon Homologation from Alkyl Amines.
Journal
Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393
Informations de publication
Date de publication:
20 08 2021
20 08 2021
Historique:
pubmed:
31
7
2021
medline:
31
7
2021
entrez:
30
7
2021
Statut:
ppublish
Résumé
A nickel-catalyzed deaminative cyanation of Katritzky pyridinium salts has been developed. When it is coupled with formation of the pyridinium salt from primary amines, this method enables alkyl amines to be converted to alkyl nitriles. A less toxic cyanide reagent, Zn(CN)
Identifiants
pubmed: 34328332
doi: 10.1021/acs.orglett.1c01959
pmc: PMC8653511
mid: NIHMS1754368
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6242-6245Subventions
Organisme : NIH HHS
ID : S10 OD016267
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM133395
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM103541
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM131816
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM104316
Pays : United States
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