Triformyl cholic acid and folic acid functionalized magnetic graphene oxide nanocomposites: Multiple-targeted dual-modal synergistic chemotherapy/photothermal therapy for liver cancer.
Animals
Antineoplastic Agents
/ chemistry
Cell Line, Tumor
Cholic Acids
/ chemistry
Combined Modality Therapy
/ methods
Doxorubicin
/ chemistry
Drug Carriers
/ chemistry
Drug Liberation
Drug Therapy
Ferrosoferric Oxide
/ chemistry
Folic Acid
/ chemistry
Graphite
/ chemistry
Humans
Infrared Rays
Liver Neoplasms
/ drug therapy
Magnetic Phenomena
Mice, Inbred BALB C
Nanocomposites
/ chemistry
Photothermal Therapy
Chemotherapy
Folic acid
Hepatocellular carcinoma
Multiple-targeted
Photothermal therapy
Triformyl cholic acid
Journal
Journal of inorganic biochemistry
ISSN: 1873-3344
Titre abrégé: J Inorg Biochem
Pays: United States
ID NLM: 7905788
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
27
03
2021
revised:
18
07
2021
accepted:
18
07
2021
pubmed:
31
7
2021
medline:
8
2
2022
entrez:
30
7
2021
Statut:
ppublish
Résumé
Photo-chemotherapy (PCT) reveals great potential in hepatocellular carcinoma (HCC) treatment, therefore the construct of smart PCT nano-agents with high photothermal conversion efficiency and accurate drug delivery is of great significant. Herein, a novel hybrid nanomaterial MGO-TCA-FA has been designed and constructed by grafting the triformyl cholic acid (TCA) and folic acid (FA) on the surface of Fe
Identifiants
pubmed: 34329998
pii: S0162-0134(21)00205-1
doi: 10.1016/j.jinorgbio.2021.111558
pii:
doi:
Substances chimiques
Antineoplastic Agents
0
Cholic Acids
0
Drug Carriers
0
graphene oxide
0
Graphite
7782-42-5
Doxorubicin
80168379AG
Folic Acid
935E97BOY8
Ferrosoferric Oxide
XM0M87F357
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
111558Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.