Cytochrome

Binding Sites / drug effects Cytochrome P-450 CYP3A / metabolism Cytochrome P-450 Enzyme Inhibitors / pharmacokinetics Cytochrome P-450 Enzyme System / classification Cytochrome-B(5) Reductase / metabolism Cytochromes b5 / metabolism Endoplasmic Reticulum / metabolism Fluoresceins / pharmacokinetics Fluorescent Dyes / pharmacokinetics Humans Microsomes, Liver / metabolism NADPH-Ferrihemoprotein Reductase / metabolism Radioligand Assay / methods Sulfonic Acids / pharmacokinetics

Journal

Drug metabolism and disposition: the biological fate of chemicals
ISSN: 1521-009X
Titre abrégé: Drug Metab Dispos
Pays: United States
ID NLM: 9421550

Informations de publication

Date de publication:
10 2021
Historique:
received: 19 03 2021
accepted: 13 07 2021
pubmed: 1 8 2021
medline: 19 3 2022
entrez: 31 7 2021
Statut: ppublish

Résumé

Numerous studies have been reported in the past 50-plus years regarding the stimulatory role of cytochrome

Identifiants

DOI: 10.1124/dmd.121.000475 PMID: 34330716 PMC: PMC8626640
pubmed: 34330716
pii: dmd.121.000475
doi: 10.1124/dmd.121.000475
pmc: PMC8626640
doi:

Substances chimiques

Cytochrome P-450 Enzyme Inhibitors 0
Fluoresceins 0
Fluorescent Dyes 0
Sulfonic Acids 0
alexa fluor 488 0
Cytochromes b5 9035-39-6
Cytochrome P-450 Enzyme System 9035-51-2
Cytochrome P-450 CYP3A EC 1.14.14.1
Cytochrome-B(5) Reductase EC 1.6.2.2
NADPH-Ferrihemoprotein Reductase EC 1.6.2.4

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

902-909

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM118122
Pays : United States

Informations de copyright

Copyright © 2021 by The American Society for Pharmacology and Experimental Therapeutics.

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Auteurs

Donghak Kim (D)

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 (D.K., Y.T., F.P.G.), and Department of Biological Sciences, Konkuk University, Seoul, Republic of Korea (D.K., V.K.).

Vitchan Kim (V)

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 (D.K., Y.T., F.P.G.), and Department of Biological Sciences, Konkuk University, Seoul, Republic of Korea (D.K., V.K.).

Yasuhiro Tateishi (Y)

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 (D.K., Y.T., F.P.G.), and Department of Biological Sciences, Konkuk University, Seoul, Republic of Korea (D.K., V.K.).

F Peter Guengerich (FP)

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 (D.K., Y.T., F.P.G.), and Department of Biological Sciences, Konkuk University, Seoul, Republic of Korea (D.K., V.K.) f.guengerich@vanderbilt.edu.

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › Cytochrome
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochrome P-450 enzyme system › Famille-3 de cytochromes P450 › Cytochrome P-450 CYP3A › Cytochrome
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs des enzymes du cytochrome P-450 › Cytochrome
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochrome P-450 enzyme system › Cytochrome
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Flavoprotéines › Cytochrome-B(5) reductase › Cytochrome
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochromes de type b › Cytochromes b5 › Cytochrome
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Réticulum endoplasmique › Cytochrome
questionsmedicales.fr › Composés polycycliques › Spiranes › Fluorescéines › Cytochrome
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › Cytochrome
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cytochrome
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Microsomes › Microsomes du foie › Cytochrome
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › NADH, NADPH oxidoreductases › Cytochrome reductases › NADPH-ferrihemoprotéine reductase › Cytochrome
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Dosage par compétition › Cytochrome
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Acides du soufre › Acides sulfoniques › Cytochrome