Specific electromagnetic radiation in the wireless signal range increases wakefulness in mice.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
03 08 2021
Historique:
entrez: 31 7 2021
pubmed: 1 8 2021
medline: 15 12 2021
Statut: ppublish

Résumé

Electromagnetic radiation (EMR) in the environment has increased sharply in recent decades. The effect of environmental EMR on living organisms remains poorly characterized. Here, we report the impact of wireless-range EMR on the sleep architecture of mouse. Prolonged exposure to 2.4-GHz EMR modulated by 100-Hz square pulses at a nonthermal output level results in markedly increased time of wakefulness in mice. These mice display corresponding decreased time of nonrapid eye movement (NREM) and rapid eye movement (REM). In contrast, prolonged exposure to unmodulated 2.4-GHz EMR at the same time-averaged output level has little impact on mouse sleep. These observations identify alteration of sleep architecture in mice as a specific physiological response to prolonged wireless-range EMR exposure.

Identifiants

pubmed: 34330835
pii: 2105838118
doi: 10.1073/pnas.2105838118
pmc: PMC8346830
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2021 the Author(s). Published by PNAS.

Déclaration de conflit d'intérêts

The authors declare no competing interest.

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Auteurs

Lingyu Liu (L)

Beijing Advanced Innovation Center for Structural Biology and Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Hu Deng (H)

Beijing Advanced Innovation Center for Structural Biology and Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Peking University HuiLongGuan Clinical Medical School, Beijing Huilongguan Hospital, Beijing 100096, China.

Xiaping Tang (X)

Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou 310024, China.
Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China.

Yingxian Lu (Y)

Beijing Advanced Innovation Center for Structural Biology and Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Jiayao Zhou (J)

Beijing Advanced Innovation Center for Structural Biology and Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Xiaofei Wang (X)

Beijing Advanced Innovation Center for Structural Biology and Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

Yanyu Zhao (Y)

Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou 310024, China.
Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China.

Bing Huang (B)

Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou 310024, China.
Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China.

Yigong Shi (Y)

Beijing Advanced Innovation Center for Structural Biology and Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China; syg@westlake.edu.cn.
Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou 310024, China.
Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Institute of Biology, Westlake Institute for Advanced Study, Hangzhou 310024, China.

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