Long-Term Outcome After Midline Lumbar Fusion for the Treatment of Lumbar Spine Instability Due to Degenerative Disease.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
10 2021
Historique:
received: 16 04 2021
revised: 21 07 2021
accepted: 22 07 2021
pubmed: 1 8 2021
medline: 18 12 2021
entrez: 31 7 2021
Statut: ppublish

Résumé

Midline lumbar fusion (MIDLF) is one promising new surgical technique that has been developed to minimize perioperative damage to the paravertebral stabilizing musculotendinous system. The aim of this study was to assess long-term clinical and radiological effects of MIDLF. This prospective cohort study evaluated patients who underwent MIDLF for degenerative spinal instability. Clinical and radiological examinations were performed before and after surgery. Perioperative and postoperative complications were recorded. Follow-up was 2 years. P ≤ 0.05 was considered statistically significant. The study included 64 patients (mean age 58.9 ± 10.7 years; 41 women [64.1%]). The most frequent indication for MIDLF was degenerative spondylolisthesis grade I (28 cases [43.8%]); the prevalent spinal segment to be fused was L4-L5 (35 cases [54.7%]). Mean duration of surgery was 148.2 ± 28.9 minutes. Relief of low back pain and leg pain was significant and stable in the postoperative period as assessed by visual analog scale (P < 0.001). Of patients, 86.9% reported fair, good, or excellent outcomes in terms of pain relief based on MacNab score 2 years after surgery. Patients' level of function in activities of daily living improved significantly based on Oswestry Disability Index score: from 66.8 ± 9.8 before surgery to 33.9 ± 16.5 2 years after surgery (P < 0.001). X-rays and computed tomography at 12 months showed interbody fusion in 46 cases (73.4%), inconclusive results in 13 cases (20.3%), and no fusion in 4 cases (6.3%). No damage to neural or vascular structures and no failure of hardware or screw loosening were recorded. MIDLF is a safe, efficient method for surgical treatment of lumbar spine instability. Its limited invasiveness contributes to better preservation of paravertebral muscles and enhanced postoperative spinal stability.

Sections du résumé

BACKGROUND
Midline lumbar fusion (MIDLF) is one promising new surgical technique that has been developed to minimize perioperative damage to the paravertebral stabilizing musculotendinous system. The aim of this study was to assess long-term clinical and radiological effects of MIDLF.
METHODS
This prospective cohort study evaluated patients who underwent MIDLF for degenerative spinal instability. Clinical and radiological examinations were performed before and after surgery. Perioperative and postoperative complications were recorded. Follow-up was 2 years. P ≤ 0.05 was considered statistically significant.
RESULTS
The study included 64 patients (mean age 58.9 ± 10.7 years; 41 women [64.1%]). The most frequent indication for MIDLF was degenerative spondylolisthesis grade I (28 cases [43.8%]); the prevalent spinal segment to be fused was L4-L5 (35 cases [54.7%]). Mean duration of surgery was 148.2 ± 28.9 minutes. Relief of low back pain and leg pain was significant and stable in the postoperative period as assessed by visual analog scale (P < 0.001). Of patients, 86.9% reported fair, good, or excellent outcomes in terms of pain relief based on MacNab score 2 years after surgery. Patients' level of function in activities of daily living improved significantly based on Oswestry Disability Index score: from 66.8 ± 9.8 before surgery to 33.9 ± 16.5 2 years after surgery (P < 0.001). X-rays and computed tomography at 12 months showed interbody fusion in 46 cases (73.4%), inconclusive results in 13 cases (20.3%), and no fusion in 4 cases (6.3%). No damage to neural or vascular structures and no failure of hardware or screw loosening were recorded.
CONCLUSIONS
MIDLF is a safe, efficient method for surgical treatment of lumbar spine instability. Its limited invasiveness contributes to better preservation of paravertebral muscles and enhanced postoperative spinal stability.

Identifiants

pubmed: 34332153
pii: S1878-8750(21)01117-7
doi: 10.1016/j.wneu.2021.07.108
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e641-e648

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Filip Samal (F)

Neurosurgical Clinic, Kralovske Vinohrady University Hospital, Prague, Czech Republic; Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Albert Sterba (A)

Neurosurgical Clinic, Kralovske Vinohrady University Hospital, Prague, Czech Republic; Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Pavel Haninec (P)

Neurosurgical Clinic, Kralovske Vinohrady University Hospital, Prague, Czech Republic; Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Patrik Jurek (P)

Department of Neurosurgery, Tomas Bata Regional Hospital, Zlin, Czech Republic.

Petr Waldauf (P)

Third Faculty of Medicine, Charles University, Prague, Czech Republic; Clinic of Anesthesiology and Resuscitation, University Hospital Kralovske Vinohrady, Prague, Czech Republic.

Michal Filip (M)

Department of Neurosurgery, Tomas Bata Regional Hospital, Zlin, Czech Republic; Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic.

Petr Linzer (P)

Department of Neurosurgery, Tomas Bata Regional Hospital, Zlin, Czech Republic. Electronic address: petrlinzer@volny.cz.

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