SIR Dynamics with Vaccination in a Large Configuration Model.
Configuration model
Epidemic
Optimal control
SIR-V
Journal
Applied mathematics and optimization
ISSN: 0095-4616
Titre abrégé: Appl Math Optim
Pays: United States
ID NLM: 9875919
Informations de publication
Date de publication:
2021
2021
Historique:
accepted:
06
07
2021
medline:
3
8
2021
pubmed:
3
8
2021
entrez:
2
8
2021
Statut:
ppublish
Résumé
We consider an SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of optimal controls for the limiting equations formulated in the framework of game theory, both in the centralized and decentralized setting. We show how the characteristics of the graph (degree distribution) influence the vaccination efficiency for optimal strategies, and we compute the limiting final size of the epidemic depending on the degree distribution of the graph and the parameters of infection, recovery and vaccination. We also present several simulations for two types of vaccination, showing how the optimal controls allow to decrease the number of infections and underlining the crucial role of the network characteristics in the propagation of the disease and the vaccination program.
Identifiants
pubmed: 34334841
doi: 10.1007/s00245-021-09810-7
pii: 9810
pmc: PMC8308122
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1769-1818Informations de copyright
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021.