The Auxiliary Diagnosis and Imaging Characteristics of MRI Combined with CT in Patients with Cholangiocarcinoma.
Journal
Journal of oncology
ISSN: 1687-8450
Titre abrégé: J Oncol
Pays: Egypt
ID NLM: 101496537
Informations de publication
Date de publication:
2021
2021
Historique:
received:
18
06
2021
revised:
05
07
2021
accepted:
11
07
2021
entrez:
2
8
2021
pubmed:
3
8
2021
medline:
3
8
2021
Statut:
epublish
Résumé
Patients with cholangiocarcinoma (CCA) have poor prognosis and high mortality. Therefore, early detection and early diagnosis are extremely important to control the development of CCA. This study aims to explore the diagnostic effect in patients with CCA and imaging characteristics of MRI combined with CT. 109 patients with suspected CCA underwent CT and MRI before diagnosis. The examination results were compared with the "gold standard." ROC curve was drawn to analyze the diagnostic efficacy of MRI combined with CT for CCA patients. The diagnosis rate of suspected CCA patients was 95.41%. The diagnostic coincidence rate of CT and MRI examination was 89.42% and 92.31%, respectively. The diagnostic coincidence rate of MRI combined with CT examination was 100.00%. The number of CT delayed enhancement, peripheral bile duct dilatation, and hepatic capsular depression were more than those of MRI. The number of circular enhancement cases in the CT group was less than that in the MRI group. ROC curve results showed that the sensitivity and specificity of MRI combined with CT for the diagnosis of CCA patients were higher than those of MRI or CT alone. MRI combined with CT has high diagnostic sensitivity and specificity and can provide imaging evidence for the clinical diagnosis and treatment of CCA.
Sections du résumé
BACKGROUND
BACKGROUND
Patients with cholangiocarcinoma (CCA) have poor prognosis and high mortality. Therefore, early detection and early diagnosis are extremely important to control the development of CCA. This study aims to explore the diagnostic effect in patients with CCA and imaging characteristics of MRI combined with CT.
METHODS
METHODS
109 patients with suspected CCA underwent CT and MRI before diagnosis. The examination results were compared with the "gold standard." ROC curve was drawn to analyze the diagnostic efficacy of MRI combined with CT for CCA patients.
RESULTS
RESULTS
The diagnosis rate of suspected CCA patients was 95.41%. The diagnostic coincidence rate of CT and MRI examination was 89.42% and 92.31%, respectively. The diagnostic coincidence rate of MRI combined with CT examination was 100.00%. The number of CT delayed enhancement, peripheral bile duct dilatation, and hepatic capsular depression were more than those of MRI. The number of circular enhancement cases in the CT group was less than that in the MRI group. ROC curve results showed that the sensitivity and specificity of MRI combined with CT for the diagnosis of CCA patients were higher than those of MRI or CT alone.
CONCLUSION
CONCLUSIONS
MRI combined with CT has high diagnostic sensitivity and specificity and can provide imaging evidence for the clinical diagnosis and treatment of CCA.
Identifiants
pubmed: 34335752
doi: 10.1155/2021/2790958
pmc: PMC8315873
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2790958Informations de copyright
Copyright © 2021 Jing Li et al.
Déclaration de conflit d'intérêts
The authors declare that they have no conflicts of interest.
Références
Circ Res. 2018 Sep 14;123(7):825-848
pubmed: 30355078
Medicine (Baltimore). 2019 Jul;98(30):e16332
pubmed: 31348232