Monaldi cavernostomy for lung aspergillosis: A case report.
cavernostomy
mycetoma
pulmonary aspergillosis
pulmonary suppuration
respiratory failure
Journal
Experimental and therapeutic medicine
ISSN: 1792-1015
Titre abrégé: Exp Ther Med
Pays: Greece
ID NLM: 101531947
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
22
01
2021
accepted:
22
02
2021
entrez:
2
8
2021
pubmed:
3
8
2021
medline:
3
8
2021
Statut:
ppublish
Résumé
Pulmonary aspergillosis in patients with respiratory failure can severely affect the pulmonary functional status and may aggravate it through pulmonary suppuration, by recruitment of new parenchyma and hemoptysis, which can sometimes be massive, with lethal risk by flooding the bronchus. The treatment consists of a combination of medical therapy, surgery and interventional radiology. In small lesions, less than 2-3 cm, medical therapy methods may be sufficient; however, in invasive forms (larger than 3 cm) surgical resection is necessary. Surgical resection is the ideal treatment; nevertheless, when lung function does not allow it, action must be taken to eliminate the favorable conditions of the infection. In such cases, whenever the lung cavity is peripheral, a cavernostomy may be performed. Four cases of lung cavernous lesions colonized with aspergillus, in which the need for a therapeutic gesture was imposed by repeated small to medium hemoptysis and by the progression of respiratory failure, were evaluated, one of which is presented in the current study. Cavernostomy closure can be realized either surgically with muscle flap or spontaneously by scarring, after closure of the bronchial fistulas by epithelization and granulation. There were no recurrences of hemoptysis or suppurative phenomena. There was one death, a patient with severe respiratory failure caused by superinfection with nonspecific germs. However, in the case presented in this study, the patient recovered following cavernostomy, which seems to be an effective and safe method for cases in which lung resection is not feasible.
Identifiants
pubmed: 34335899
doi: 10.3892/etm.2021.10389
pii: ETM-0-0-10389
pmc: PMC8290423
doi:
Types de publication
Journal Article
Langues
eng
Pagination
957Informations de copyright
Copyright: © Petreanu et al.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interests.
Références
Medicine (Baltimore). 1982 Mar;61(2):109-24
pubmed: 7038373
Clin Infect Dis. 2008 Feb 1;46(3):327-60
pubmed: 18177225
Eur J Radiol. 1998 Oct;28(3):235-42
pubmed: 9881259
Ann Thorac Surg. 1992 Dec;54(6):1159-64
pubmed: 1449303
J Thorac Imaging. 1992 Sep;7(4):56-74
pubmed: 1404546
Chest. 2014 Nov;146(5):1358-1368
pubmed: 25367472
Am Rev Tuberc. 1952 Jan;65(1:1):83-7
pubmed: 14885710
Am J Med. 1980 Mar;68(3):389-94
pubmed: 7361807
Respir Med. 2012 May;106(5):724-9
pubmed: 22349065
J Cardiothorac Surg. 2011 Oct 05;6:129
pubmed: 21974978
N Engl J Med. 1991 Mar 7;324(10):654-62
pubmed: 1994248
Thorax. 1991 Nov;46(11):839-41
pubmed: 1663275
Kardiochir Torakochirurgia Pol. 2017 Jun;14(2):99-103
pubmed: 28747940
Ann Thorac Surg. 2004 Nov;78(5):1846-8
pubmed: 15511496
Radiology. 1993 Sep;188(3):821-3
pubmed: 8351355
Eur Respir J. 2019 Mar 18;53(3):
pubmed: 30705126
Eur J Cardiothorac Surg. 2004 Nov;26(5):1043
pubmed: 15519206
J Cardiothorac Surg. 2013 Aug 05;8:180
pubmed: 23915502
Clin Infect Dis. 2000 Apr;30(4):696-709
pubmed: 10770732
Eur J Cardiothorac Surg. 2005 May;27(5):737-40
pubmed: 15848306
Swiss Med Wkly. 2006 Jul 22;136(29-30):447-63
pubmed: 16937323
Thorax. 1997 Sep;52(9):810-3
pubmed: 9371213
Tubercle. 1957 Jun;38(3):203-9
pubmed: 13455778
Chest. 2002 Jun;121(6):1988-99
pubmed: 12065367
J Infect Chemother. 2014 Mar;20(3):208-12
pubmed: 24477329
Med Mycol. 2013 Nov;51(8):811-7
pubmed: 23834282
Asian Cardiovasc Thorac Ann. 2004 Sep;12(3):246-9
pubmed: 15353465
Rev Col Bras Cir. 2014 Nov-Dec;41(6):406-11
pubmed: 25742406
Ann Surg. 1977 Jul;186(1):13-16
pubmed: 327952
J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):703-8
pubmed: 25439360
Thorax. 1983 Aug;38(8):572-8
pubmed: 6612647
J Thorac Cardiovasc Surg. 2009 Oct;138(4):820-5
pubmed: 19660294
QJM. 2007 Jun;100(6):317-34
pubmed: 17525130
Thorax. 2015 Mar;70(3):270-7
pubmed: 25354514
J Thorac Cardiovasc Surg. 1969 May;57(5):642-7
pubmed: 5782409
Eur Respir Rev. 2011 Sep 1;20(121):156-74
pubmed: 21881144
Rev Fr Mal Respir. 1983;11(3):201-7
pubmed: 6878847
J Infect Chemother. 2004 Jun;10(3):138-45
pubmed: 15290452
Medicina (Kaunas). 2020 Apr 16;56(4):
pubmed: 32316178
Adv Respir Med. 2019;87(6):231-243
pubmed: 31970725
Case Rep Surg. 2015;2015:614795
pubmed: 26576311
Eur Respir J. 2016 Jan;47(1):45-68
pubmed: 26699723
Ann Thorac Surg. 2014 Jul;98(1):360-1
pubmed: 24996732
Ann Thorac Surg. 2000 Mar;69(3):898-903
pubmed: 10750780
Ugeskr Laeger. 2018 Jan 29;180(5):
pubmed: 29393028
Ann Pharmacother. 2014 Jun 17;48(9):1225-1229
pubmed: 24939635