Magnetic Resonance Imaging-Guided Focused Ultrasound-Based Delivery of Radiolabeled Copper Nanoclusters to Diffuse Intrinsic Pontine Glioma.

diffuse intrinsic pontine glioma focused ultrasound magnetic resonance imaging nanoclusters positron emission tomography

Journal

ACS applied nano materials
ISSN: 2574-0970
Titre abrégé: ACS Appl Nano Mater
Pays: United States
ID NLM: 101726750

Informations de publication

Date de publication:
25 Nov 2020
Historique:
entrez: 2 8 2021
pubmed: 3 8 2021
medline: 3 8 2021
Statut: ppublish

Résumé

Diffuse intrinsic pontine glioma (DIPG) is an invasive pediatric brainstem malignancy exclusively in children without effective treatment due to the often-intact blood-brain tumor barrier (BBTB), an impediment to the delivery of therapeutics. Herein, we used focused ultrasound (FUS) to transiently open BBTB and delivered radiolabeled nanoclusters (

Identifiants

pubmed: 34337344
doi: 10.1021/acsanm.0c02297
pmc: PMC8320805
mid: NIHMS1671401
doi:

Types de publication

Journal Article

Langues

eng

Pagination

11129-11134

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB027223
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH116981
Pays : United States

Déclaration de conflit d'intérêts

Notes The authors declare no conflict of interest.

Références

Oncotarget. 2017 Jul 28;8(44):76644-76655
pubmed: 29100338
Nano Lett. 2009 Sep;9(9):3337-42
pubmed: 19640002
ACS Appl Mater Interfaces. 2019 Jun 5;11(22):19669-19678
pubmed: 31074257
Front Pharmacol. 2019 Feb 07;10:86
pubmed: 30792657
J Cereb Blood Flow Metab. 2014 Jul;34(7):1197-204
pubmed: 24780905
ACS Nano. 2019 Apr 23;13(4):4028-4040
pubmed: 30916923
Brain Pathol. 2011 Jul;21(4):441-51
pubmed: 21159008
Curr Neuropharmacol. 2017;15(1):104-115
pubmed: 26903150
Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):E10281-E10290
pubmed: 29133392
Curr Pharm Biotechnol. 2012 Jun;13(7):1332-45
pubmed: 22201586
Br J Radiol. 2018 Jul;91(1087):20170481
pubmed: 29419328
Cancer Res. 2017 Apr 15;77(8):2112-2123
pubmed: 28108511
Sci Transl Med. 2016 Jun 15;8(343):343re2
pubmed: 27306666
J Neurooncol. 1992 Jan;12(1):33-46
pubmed: 1541977
J Control Release. 2018 Sep 28;286:145-153
pubmed: 30009893
J Neurosurg. 2020 Jan 3;:1-9
pubmed: 31899873
Neoplasia. 2016 Jan;18(1):60-70
pubmed: 26806352
Small. 2018 Jul;14(30):e1703115
pubmed: 29966035
Front Pharmacol. 2017 Jul 25;8:495
pubmed: 28790919
Front Oncol. 2015 Oct 21;5:237
pubmed: 26557503
Mol Cancer Ther. 2016 Sep;15(9):2166-74
pubmed: 27325687
J Control Release. 2018 Aug 10;283:143-150
pubmed: 29864474
Circ Res. 2019 Mar 15;124(6):881-890
pubmed: 30661445
PLoS One. 2017 Jun 5;12(6):e0178593
pubmed: 28582410
Neurotherapeutics. 2017 Apr;14(2):358-371
pubmed: 28299724
Chem Soc Rev. 2019 Jun 4;48(11):2967-3014
pubmed: 31089607
CNS Drugs. 2017 Feb;31(2):109-133
pubmed: 28101766
Nat Commun. 2018 Jul 25;9(1):2336
pubmed: 30046032
Front Oncol. 2018 Jul 03;8:239
pubmed: 30018882
J Control Release. 2018 Dec 10;291:37-64
pubmed: 30308256
Front Oncol. 2015 Jul 24;5:172
pubmed: 26258075
IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Nov;60(11):2257-65
pubmed: 24158283
J Control Release. 2018 Jul 10;281:29-41
pubmed: 29753957
Anticancer Res. 2014 Feb;34(2):565-74
pubmed: 24510985
Adv Sci (Weinh). 2018 Jan 10;5(4):1700474
pubmed: 29721406

Auteurs

Xiaohui Zhang (X)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Department of Neurosurgery, Washington University in St. Louis, Saint Louis, MO 63110, USA.

Dezhuang Ye (D)

Department of Mechanical Engineering and Material Science, Washington University in St. Louis, Saint Louis, MO 63130, USA.
Department of Neurosurgery, Washington University in St. Louis, Saint Louis, MO 63110, USA.

Lihua Yang (L)

Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.

Yimei Yue (Y)

Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, MO 63130, USA.

Deborah Sultan (D)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Christopher Pham Pacia (CP)

Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, MO 63130, USA.

Hannah Pang (H)

Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, MO 63130, USA.

Lisa Detering (L)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Gyu Seong Heo (GS)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Hannah Luehmann (H)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Ankur Choksi (A)

School of Medicine, University of Maryland, Baltimore, MD, 21201, USA.

Abhishek Sethi (A)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

David D Limbrick (DD)

Department of Neurosurgery, Washington University in St. Louis, Saint Louis, MO 63110, USA.

Oren J Becher (OJ)

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Yuan-Chuan Tai (YC)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Joshua B Rubin (JB)

Department of Pediatrics, Washington University School of Medicine, St. Louis, MO 63110, USA.
Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA.

Hong Chen (H)

Department of Biomedical Engineering, Washington University in St. Louis, Saint Louis, MO 63130, USA.
Department of Radiation Oncology, Washington University School of Medicine, Saint Louis, MO 63108, USA.

Yongjian Liu (Y)

Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

Classifications MeSH