Intestinal alteration of α-gustducin and sweet taste signaling pathway in metabolic diseases is partly rescued after weight loss and diabetes remission.

Animals Diabetes Mellitus, Type 2 / metabolism Dysbiosis / metabolism Enteroendocrine Cells / metabolism Gastrointestinal Microbiome Humans Male Mice, Inbred C57BL Obesity / metabolism Signal Transduction Taste Transducin / metabolism
intestinal endocrine cells microbiota obesity type 2 diabetes α-gustducin

Journal

American journal of physiology. Endocrinology and metabolism
ISSN: 1522-1555
Titre abrégé: Am J Physiol Endocrinol Metab
Pays: United States
ID NLM: 100901226

Informations de publication

Date de publication:
01 09 2021
Historique:
pubmed: 3 8 2021
medline: 22 9 2021
entrez: 2 8 2021
Statut: ppublish

Résumé

Carbohydrates and sweeteners are detected by the sweet taste receptor in enteroendocrine cells (EECs). This receptor is coupled to the gustducin G-protein, which α-subunit is encoded by

Identifiants

DOI: 10.1152/ajpendo.00071.2021 PMID: 34338041
pubmed: 34338041
doi: 10.1152/ajpendo.00071.2021
doi:

Substances chimiques

gustducin 147979-21-3
Transducin EC 3.6.5.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

E417-E432

Auteurs

Léa Le Gléau (L)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
ORCID: 0000-0002-6245-5807

Christine Rouault (C)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.

Céline Osinski (C)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
ORCID: 0000-0003-4897-8510

Edi Prifti (E)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
IRD, Sorbonne University, UMMISCO, Bondy, France.

Hédi Antoine Soula (HA)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.

Jean Debédat (J)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
ORCID: 0000-0002-8377-5965

Pauline Busieau (P)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.

Chloé Amouyal (C)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
Assistance Publique/Hôpitaux de Paris, APHP, Nutrition Department, Pitié-Salpêtrière Hospital, Paris, France.
Assistance Publique-Hôpitaux de Paris, APHP, Diabetology-Metabolisms Department, Pitié-Salpêtrière Hospital, Paris, France.

Karine Clément (K)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
Assistance Publique/Hôpitaux de Paris, APHP, Nutrition Department, Pitié-Salpêtrière Hospital, Paris, France.

Fabrizio Andreelli (F)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
Assistance Publique/Hôpitaux de Paris, APHP, Nutrition Department, Pitié-Salpêtrière Hospital, Paris, France.
Assistance Publique-Hôpitaux de Paris, APHP, Diabetology-Metabolisms Department, Pitié-Salpêtrière Hospital, Paris, France.

Agnès Ribeiro (A)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
ORCID: 0000-0003-2063-6084

Patricia Serradas (P)

Sorbonne Université, INSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Paris, France.
ORCID: 0000-0002-6652-9746

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Diabète de type 2 › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Dysbiose › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules entéroendocrines › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Sensation › Goût › Intestinal alteration of α-gustducin and sweet...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines G hétérotrimériques › Transducine › Intestinal alteration of α-gustducin and sweet...