Telemonitoring, Telemedicine and Time in Range During the Pandemic: Paradigm Change for Diabetes Risk Management in the Post-COVID Future.

Ambulatory glucose profile COVID-19 Continuous glucose monitoring Diabetes Insulin pumps Mortality Risk management Telemedicine Telemonitoring Virtual care

Journal

Diabetes therapy : research, treatment and education of diabetes and related disorders
ISSN: 1869-6953
Titre abrégé: Diabetes Ther
Pays: United States
ID NLM: 101539025

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 27 05 2021
accepted: 01 07 2021
pubmed: 3 8 2021
medline: 3 8 2021
entrez: 2 8 2021
Statut: ppublish

Résumé

People with diabetes are at greater risk for negative outcomes from COVID-19. Though this risk is multifactorial, poor glycaemic control before and during admission to hospital for COVID-19 is likely to contribute to the increased risk. The COVID-19 pandemic and restrictions on mobility and interaction can also be expected to impact on daily glucose management of people with diabetes. Telemonitoring of glucose metrics has been widely used during the pandemic in people with diabetes, including adults and children with T1D, allowing an exploration of the impact of COVID-19 inside and outside the hospital setting on glycaemic control. To date, 27 studies including 69,294 individuals with T1D have reported the effect of glycaemic control during the COVID-19 pandemic. Despite restricted access to diabetes clinics, glycaemic control has not deteriorated for 25/27 cohorts and improved in 23/27 study groups. Significantly, time in range (TIR) 70-180 mg/dL (3.9-10 mmol/L) increased across 19/27 cohorts with a median 3.3% (- 6.0% to 11.2%) change. Thirty per cent of the cohorts with TIR data reported an average clinically significant TIR improvement of 5% or more, possibly as a consequence of more accurate glucose monitoring and improved connectivity through telemedicine. Periodic consultations using telemedicine enables care of people with diabetes while limiting the need for in-person attendance at diabetes clinics. Reports that sustained hyperglycaemia and early-stage diabetic ketoacidosis may go untreated because of the lockdown and concerns about potential exposure to the risk of infection argue for wider access to glucose telemonitoring. Therefore, in this paper we have critically reviewed reports concerning use of telemonitoring in the acute hospitalized setting as well as during daily diabetes management. Furthermore, we discuss the indications and implications of adopting telemonitoring and telemedicine in the present challenging time, as well as their potential for the future.

Identifiants

pubmed: 34338994
doi: 10.1007/s13300-021-01114-x
pii: 10.1007/s13300-021-01114-x
pmc: PMC8327601
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

2289-2310

Informations de copyright

© 2021. The Author(s).

Références

Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395:1054–62.
pubmed: 7270627 pmcid: 7270627 doi: 10.1016/S0140-6736(20)30566-3
Bode B, Garrett V, Messler J, et al. Glycemic characteristics and clinical outcomes of COVID-19 patients hospitalized in the United States. J Diabetes Sci Technol. 2020;14:813–21.
pubmed: 32389027 pmcid: 7673150 doi: 10.1177/1932296820924469
Chen Y, Yang D, Cheng B, et al. Clinical characteristics and outcomes of patients with diabetes and COVID-19 in association with glucose-lowering medication. Diabetes Care. 2020;43:1399–407.
pubmed: 32409498 doi: 10.2337/dc20-0660 pmcid: 32409498
Holman N, Knighton P, Kar P, et al. Risk factors for COVID-19-related mortality in people with type 1 and type 2 diabetes in England: a population-based cohort study. Lancet Diabetes Endocrinol. 2020;8:823–33.
pubmed: 32798471 pmcid: 7426091 doi: 10.1016/S2213-8587(20)30271-0
Istituto Superiore di Sanità. Report of characteristics of patients who died positive for COVID-19 in Italy. 2020 (in Italian). https://www.epicentro.iss.it/coronavirus/bollettino/Report-COVID-2019_17_marzo-v2.pdf . Accessed 18 June 2021.
Mantovani A, Byrne CD, Zheng M-H, Targher G. Diabetes as a risk factor for greater COVID-19 severity and in-hospital death: a meta-analysis of observational studies. Nutrition Metab Cardiovasc Dis. 2020;30:1236–48.
doi: 10.1016/j.numecd.2020.05.014
Barron E, Bakhai C, Kar P, et al. Associations of type 1 and type 2 diabetes with COVID-19-related mortality in England: a whole-population study. Lancet Diabetes Endocrinol. 2020;8:813–22.
pubmed: 32798472 pmcid: 7426088 doi: 10.1016/S2213-8587(20)30272-2
McGurnaghan SJ, Weir A, Bishop J, et al. Risks of and risk factors for COVID-19 disease in people with diabetes: a cohort study of the total population of Scotland. Lancet Diabetes Endocrinol. 2021;9:82–93.
pubmed: 33357491 doi: 10.1016/S2213-8587(20)30405-8 pmcid: 33357491
Danne T, Limbert C. COVID-19 pandemic, type 1 diabetes and technology: why paediatric patients are leading the way. Lancet Diabetes Endocrinol. 2020;8:465–7. https://doi.org/10.1016/S2213-8587[20]30155-8 .
doi: 10.1016/S2213-8587[20]30155-8 pmcid: 7200123
Cardona-Hernandez R, Cherubini V, Iafusco D, Schiaffini R, Luo X, Maahs DM. Children and youth with diabetes are not at increased risk for hospitalization due to COVID-19. Pediatr Diabetes. 2021;22:202–6.
pubmed: 33205546 doi: 10.1111/pedi.13158
Wake DJ, Gibb FW, Kar P, et al. Endocrinology in the time of COVID-19: remodelling diabetes services and emerging innovation. Eur J Endocrinol. 2020;183:G67-77.
pubmed: 32508313 pmcid: 7938018 doi: 10.1530/EJE-20-0377
Danne T, Nimri R, Battelino T, et al. International consensus on use of continuous glucose monitoring. Diabetes Care. 2017;40(12):1631–40.
pubmed: 29162583 pmcid: 6467165 doi: 10.2337/dc17-1600
Battelino T, Danne T, Bergenstal RM, et al. Clinical targets for continuous glucose monitoring data interpretation: recommendations from the international consensus on time in range. Diabetes Care. 2019;42(8):1593–603.
Barchetta I, Cimini FA, Bertoccini L, et al. Effects of work status changes and perceived stress on glycaemic control in individuals with type 1 diabetes during COVID-19 lockdown in Italy. Diabetes Res Clin Pract. 2020;170:108513.
pubmed: 33075424 pmcid: 7566668 doi: 10.1016/j.diabres.2020.108513
Mesa A, Viñals C, Pueyo I, et al. The impact of strict COVID-19 lockdown in Spain on glycemic profiles in patients with type 1 diabetes prone to hypoglycemia using standalone continuous glucose monitoring. Diabetes Res Clin Pract. 2020;167:108354.
pubmed: 32739380 pmcid: 7392049 doi: 10.1016/j.diabres.2020.108354
Viñals C, Mesa A, Roca D, et al. Management of glucose profile throughout strict COVID-19 lockdown by patients with type 1 diabetes prone to hypoglycaemia using sensor-augmented pump. Acta Diabetol. 2021;58(3):383–8. https://doi.org/10.1007/s00592-020-01625-2 .
doi: 10.1007/s00592-020-01625-2 pubmed: 33125525
Bonora BM, Boscari F, Avogaro A, Bruttomesso D, Fadini GP. Glycaemic control among people with type 1 diabetes during lockdown for the SARS-CoV-2 outbreak in Italy. Diabetes Ther. 2020;11:1369–79.
pmcid: 7213551 doi: 10.1007/s13300-020-00829-7
Prabhu Navis J, Leelarathna L, Mubita W, et al. Impact of COVID-19 lockdown on flash and real-time glucose sensor users with type 1 diabetes in England. Acta Diabetol. 2020;58(2):231–7.
Capaldo B, Annuzzi G, Creanza A, et al. Blood glucose control during lockdown for COVID-19: CGM metrics in Italian adults with type 1 diabetes. Diabetes Care. 2020;43:e88–9. https://doi.org/10.2337/dc20-1127 .
doi: 10.2337/dc20-1127 pubmed: 32540921 pmcid: 7372051
Potier L, Hansel B, Larger E, et al. Stay-at-home orders during the COVID-19 pandemic, an opportunity to improve glucose control through behavioral changes in type 1 diabetes. Diabetes Care. 2020;44:839–43.
pubmed: 33361146 doi: 10.2337/dc20-2019 pmcid: 33361146
Schiaffini R, Barbetti F, Rapini N, et al. School and pre-school children with type 1 diabetes during Covid-19 quarantine: the synergic effect of parental care and technology. Diabetes Res Clin Pract. 2020;166:108302.
pubmed: 32623034 pmcid: 7332425 doi: 10.1016/j.diabres.2020.108302
Dover AR, Ritchie SA, McKnight JA, et al. Assessment of the effect of the COVID‐19 lockdown on glycaemic control in people with type 1 diabetes using flash glucose monitoring. Diabetic Med. 2021;38(1):e14374.
Braune K, Boss K, Schmidt-Herzel J, et al. Shaping workflows in digital and remote diabetes care during the COVID-19 pandemic via a service design: prospective, longitudinal, open-label feasibility trial. JMIR Mhealth Uhealth. 2021;9(4):e24374.
Boscari F, Ferretto S, Uliana A, Avogaro A, Bruttomesso D. Efficacy of telemedicine for persons with type 1 diabetes during Covid19 lockdown. Nutr Diabetes. 2021;11:1.
pubmed: 33414391 pmcid: 7790327 doi: 10.1038/s41387-020-00147-8
Rachmiel M, Lebenthal Y, Mazor-Aronovitch K, et al. Glycaemic control in the paediatric and young adult population with type 1 diabetes following a single telehealth visit—what have we learned from the COVID-19 lockdown? Acta Diabetol. 2021;58(6):697–705.
Alharthi SK, Alyusuf EY, Alguwaihes AM, Alfadda A, Al-Sofiani ME. The impact of a prolonged lockdown and use of telemedicine on glycemic control in people with type 1 diabetes during the COVID-19 outbreak in Saudi Arabia. Diabetes Res Clin Pract. 2021;173:108682.
pubmed: 33539868 doi: 10.1016/j.diabres.2021.108682
Park S-D, Kim S-W, Moon JS, et al. Impact of social distancing due to coronavirus disease 2019 on the changes in glycosylated hemoglobin level in people with type 2 diabetes mellitus. Korean Diabetes J. 2020;45:109–14.
Karatas S, Yesim T, Beysel S. Impact of lockdown COVID-19 on metabolic control in type 2 diabetes mellitus and healthy people. Prim Care Diabetes. 2021;15:424–7.
pubmed: 33441263 pmcid: 7834877 doi: 10.1016/j.pcd.2021.01.003
Falcetta P, Aragona M, Ciccarone A, et al. Impact of COVID-19 lockdown on glucose control of elderly people with type 2 diabetes in Italy. Diabetes Res Clin Pract. 2021;174: 108750. https://doi.org/10.1016/j.diabres.2021.108750 .
doi: 10.1016/j.diabres.2021.108750 pubmed: 33722703
Rastogi A, Hiteshi P, Bhansali A. Improved glycemic control amongst people with long-standing diabetes during COVID-19 lockdown: a prospective, observational, nested cohort study. Int J Diabetes Dev Ctries. 2020;40:476–81.
doi: 10.1007/s13410-020-00880-x
Ruissen MM, Regeer H, Landstra CP, et al. Increased stress, weight gain and less exercise in relation to glycemic control in people with type 1 and type 2 diabetes during the COVID-19 pandemic. BMJ Open Diabetes Res Care. 2021;9:e002035.
pubmed: 33431602 doi: 10.1136/bmjdrc-2020-002035 pmcid: 33431602
Verma A, Rajput R, Verma S, Balania VKB, Jangra B. Impact of lockdown in COVID 19 on glycemic control in patients with type 1 diabetes mellitus. Diabetes Metab Syndrome Clin Res Rev. 2020;14:1213–6.
doi: 10.1016/j.dsx.2020.07.016
Phillip M, Bergenstal RM, Close KL, et al. The digital/virtual diabetes clinic: the future is now—recommendations from an international panel on diabetes digital technologies introduction. Diabetes Technol Ther. 2021;23:146–54.
pubmed: 32905711 doi: 10.1089/dia.2020.0375 pmcid: 32905711
Bain SC, Czernichow S, Bøgelund M, et al. Costs of COVID-19 pandemic associated with diabetes in Europe: a health care cost model. Curr Med Res Opin. 2020;37:1–16.
Stokes EK, Zambrano LD, Anderson KN, et al. Coronavirus disease 2019 case surveillance—United States, January 22–May 30, 2020. Morbidity Mortal Wkly Rep. 2020;69:759–65.
doi: 10.15585/mmwr.mm6924e2
Merzon E, Green I, Shpigelman M, et al. Haemoglobin A1c is a predictor of COVID‐19 severity in patients with diabetes. Diabetes Metabolism Res Rev. 2021;37(5):e3398.
Williamson EJ, Walker AJ, Bhaskaran K, et al. Factors associated with COVID-19-related death using OpenSAFELY. Nature. 2020;584:430–6.
pubmed: 32640463 pmcid: 32640463 doi: 10.1038/s41586-020-2521-4
Carrasco-Sánchez FJ, López-Carmona MD, Martínez-Marcos FJ, et al. Admission hyperglycaemia as a predictor of mortality in patients hospitalized with COVID-19 regardless of diabetes status: data from the Spanish SEMI-COVID-19 Registry. Ann Med. 2020;53:103–16.
pmcid: 7651248 doi: 10.1080/07853890.2020.1836566
Lampasona V, Secchi M, Scavini M, et al. Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study. Diabetologia. 2020;63:2548–58.
pubmed: 33029657 doi: 10.1007/s00125-020-05284-4
Coppelli A, Giannarelli R, Aragona M, et al. Hyperglycemia at hospital admission is associated with severity of the prognosis in patients hospitalized for COVID-19: the Pisa COVID-19 Study. Diabetes Care. 2020;43:2345–8.
pubmed: 32788285 doi: 10.2337/dc20-1380 pmcid: 32788285
Müller JA, Groß R, Conzelmann C, et al. SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas. Nat Metab. 2021;3(2):149–65.
pubmed: 33536639 doi: 10.1038/s42255-021-00347-1 pmcid: 33536639
Atkinson MA, Powers AC. Distinguishing the real from the hyperglycemia: does COVID-19 induce diabetes? Lancet Diab Endocrinol. 2021. https://doi.org/10.1016/S2213-8587(21)00087-5 .
doi: 10.1016/S2213-8587(21)00087-5
Brufsky A. Hyperglycemia, hydroxychloroquine, and the COVID-19 pandemic. J Med Virol. 2020;92:770–5.
pubmed: 32293710 doi: 10.1002/jmv.25887 pmcid: 32293710
Shen Y, Fan X, Zhang L, et al. Thresholds of glycemia and the outcomes of COVID-19 complicated with diabetes: a retrospective exploratory study using continuous glucose monitoring. Diabetes Care. 2021;44(4):976–82. https://doi.org/10.2337/dc20-1448 .
doi: 10.2337/dc20-1448 pubmed: 33574126 pmcid: 7985431
Klonoff DC, Messler JC, Umpierrez GE, et al. Association between achieving inpatient glycemic control and clinical outcomes in hospitalized patients with COVID-19: a multicenter, retrospective hospital-based analysis. Diabetes Care. 2020;44:578–85.
pubmed: 33323475 pmcid: 7818335 doi: 10.2337/dc20-1857
Papadopoulos VP, Koutroulos M-V, Zikoudi D-G, et al. Diabetes-related acute metabolic emergencies in COVID-19 patients: a systematic review and meta-analysis. Diabetol Int. 2021;23:1–15. https://doi.org/10.1007/s13340-021-00502-9 .
doi: 10.1007/s13340-021-00502-9
Yang J-K, Lin S-S, Ji X-J, Guo L-M. Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Acta Diabetol. 2010;47:193–9.
pubmed: 19333547 doi: 10.1007/s00592-009-0109-4 pmcid: 19333547
Hollstein T, Schulte DM, Schulz J, et al. Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report. Nat Metabolism. 2020;2:1021–4.
doi: 10.1038/s42255-020-00281-8
Unsworth R, Wallace S, Oliver NS, et al. New-onset type 1 diabetes in children during COVID-19: multicenter regional findings in the U.K. Diabetes Care. 2020;43(11):e170–1.
pubmed: 32816997 doi: 10.2337/dc20-1551 pmcid: 32816997
Li H, Tian S, Chen T, et al. Newly diagnosed diabetes is associated with a higher risk of mortality than known diabetes in hospitalized patients with COVID-19. Diabetes Obes Metab. 2020;22:1897–906.
pubmed: 32469464 doi: 10.1111/dom.14099
Fadini GP, Morieri ML, Boscari F, et al. Newly-diagnosed diabetes and admission hyperglycemia predict COVID-19 severity by aggravating respiratory deterioration. Diabetes Res Clin Pract. 2020;168:108374.
pubmed: 32805345 pmcid: 7428425 doi: 10.1016/j.diabres.2020.108374
Garg SK, Rodbard D, Hirsch IB, Forlenza GP. Managing new-onset type 1 diabetes during the COVID-19 pandemic: challenges and opportunities. Diabetes Technol Ther. 2020;22:431–9.
pubmed: 32302499 doi: 10.1089/dia.2020.0161
Association of British Clinical Diabetologists. Donation of Freestyle Libre Sensors. 2020. https://abcd.care/announcement/donation-freestyle-libre-sensors . Accessed 14 July 2021.
Joensen LE, Madsen KP, Holm L, et al. Diabetes and COVID-19: psychosocial consequences of the COVID-19 pandemic in people with diabetes in Denmark—what characterizes people with high levels of COVID-19-related worries? Diabetic Med. 2020;37:1146–54.
pubmed: 32392380 doi: 10.1111/dme.14319
Solomon MD, McNulty EJ, Rana JS, et al. The Covid-19 pandemic and the incidence of acute myocardial infarction. N Engl J Med. 2020;383:691–3.
pubmed: 32427432 doi: 10.1056/NEJMc2015630
Pop R, Quenardelle V, Hasiu A, et al. Impact of the COVID-19 outbreak on acute stroke pathways—insights from the Alsace region in France. Eur J Neurol. 2020;27:1783–7.
pubmed: 32399995 doi: 10.1111/ene.14316
Lazzerini M, Barbi E, Apicella A, Marchetti F, Cardinale F, Trobia G. Delayed access or provision of care in Italy resulting from fear of COVID-19. Lancet Child Adolesc Health. 2020;4:e10–1.
pubmed: 32278365 pmcid: 7146704 doi: 10.1016/S2352-4642(20)30108-5
Lynn RM, Avis JL, Lenton S, Amin-Chowdhury Z, Ladhani SN. Delayed access to care and late presentations in children during the COVID-19 pandemic: a snapshot survey of 4075 paediatricians in the UK and Ireland. Arch Dis Child. 2021;106:e8–e8.
pubmed: 32586927 doi: 10.1136/archdischild-2020-319848
Dżygało K, Nowaczyk J, Szwilling A, Kowalska A. Increased frequency of severe diabetic ketoacidosis at type 1 diabetes onset among children during COVID-19 pandemic lockdown: an observational cohort study. Pediatric Endocrinol Diabetes Metab. 2020;26:167–75.
doi: 10.5114/pedm.2020.101003
Lawrence C, Seckold R, Smart C, et al. Increased paediatric presentations of severe diabetic ketoacidosis in an Australian tertiary centre during the COVID-19 pandemic. Diabetic Med. 2021;38:e14417.
pubmed: 33020999 doi: 10.1111/dme.14417
Ho J, Rosolowsky E, Pacaud D, et al. Diabetic ketoacidosis at type 1 diabetes diagnosis in children during the COVID-19 pandemic. Pediatr Diabetes. 2021;22:552–7.
pubmed: 33745226 pmcid: 8251027 doi: 10.1111/pedi.13205
Bornstein SR, Rubino F, Khunti K, et al. Practical recommendations for the management of diabetes in patients with COVID-19. Lancet Diabetes Endocrinol. 2020;8:546–50.
pubmed: 32334646 pmcid: 7180013 doi: 10.1016/S2213-8587(20)30152-2
Laffel LM, Limbert C, Phelan H, Virmani A, Wood J, Hofer SE. ISPAD Clinical Practice Consensus Guidelines 2018: sick day management in children and adolescents with diabetes. Pediatr Diabetes. 2018;19:193–204.
pubmed: 30079506 doi: 10.1111/pedi.12741
Croft A, Bucca A, Jansen JH, et al. First-time diabetic ketoacidosis in type 2 diabetics with Covid-19 infection: a novel case series. J Emerg Med. 2020;59:e193-197.
pubmed: 32912646 pmcid: 7342034 doi: 10.1016/j.jemermed.2020.07.017
Charleer S, Block CD, Huffel LV, et al. Quality of life and glucose control after 1 year of nationwide reimbursement of intermittently scanned continuous glucose monitoring in adults living with type 1 diabetes (FUTURE): a prospective observational real-world cohort study. Diabetes Care. 2020;43:389–97.
pubmed: 31843948 doi: 10.2337/dc19-1610
Roussel R, Riveline J-P, Vicaut E, et al. Important drop in rate of acute diabetes complications in people with type 1 or type 2 diabetes after initiation of flash glucose monitoring in France: The RELIEF Study. Diabetes Care. 2021. https://doi.org/10.2337/dc20-1690 .
doi: 10.2337/dc20-1690 pubmed: 34099517
Bergenstal RM, Kerr MSD, Roberts GJ, Souto D, Nabutovsky Y, Hirsch IB. Flash CGM is associated with reduced diabetes events and hospitalizations in insulin-treated type 2 diabetes. J Endocr Soc. 2021;5:bvab013.
pubmed: 33644623 pmcid: 7901259 doi: 10.1210/jendso/bvab013
Scott SN, Fontana FY, Züger T, Laimer M, Stettler C. Use and perception of telemedicine in people with type 1 diabetes during the COVID-19 pandemic—results of a global survey. Endocrinol Diabetes Metabolism. 2021;4:e00180.
Choudhary P, Wilmot EG, Owen K, Patel DC, Mills L, et al. A roadmap to recovery: ABCD recommendations on risk stratification of adult patients with diabetes in the post-COVID-19 era. Diabet Med. 2021;38(3): e14462. https://doi.org/10.1111/dme.14462 .
doi: 10.1111/dme.14462 pubmed: 33230813
March CA, Flint A, DeArment D, Gilliland A, Kelly K, Rizzitano E, et al. Paediatric diabetes care during the COVID-19 pandemic: lessons learned in scaling up telemedicine services. Endocrinol Diabetes Metab. 2021;4:e00202.
doi: 10.1002/edm2.202
DeSalvo DJ, Miller KM, Hermann JM, Maahs DM, Hofer SE, Clements MA, et al. Continuous glucose monitoring and glycemic control among youth with type 1 diabetes: International comparison from the T1D Exchange and DPV Initiative. Pediatr Diabetes. 2018;19:1271–5.
pubmed: 29923262 pmcid: 6175652 doi: 10.1111/pedi.12711
Gerhardsson P, Schwandt A, Witsch M, Kordonouri O, Svensson J, Forsander G, Battelino T, Veeze H, Danne T. The SWEET project 10-year benchmarking in 19 countries worldwide is associated with improved HbA1c and increased use of diabetes technology in youth with type 1 diabetes. Diabetes Technol Ther. 2021. https://doi.org/10.1089/dia.2020.0618 .
doi: 10.1089/dia.2020.0618 pubmed: 33566729 pmcid: 33566729
Cardona-Hernandez R, Schwandt A, Alkandari H, et al. Glycemic outcome associated with insulin pump and glucose sensor use in children and adolescents with type 1 diabetes. Data from the international pediatric registry SWEET. Diabetes Care. 2021;44(5):1176–84.
Ohannessian R, Duong TA, Odone A. Global Telemedicine Implementation and Integration Within Health Systems to Fight the COVID-19 Pandemic: A Call to Action. JMIR Public Heal Surveillance. 2020;6:e18810.
doi: 10.2196/18810
Demeke HB, Merali S, Marks S, Pao LZ, Romero L, Sandhu P, et al. Trends in use of telehealth among health centers during the COVID-19 Pandemic—United States, June 26–November 6, 2020. Morbidity Mortal Wkly Rep. 2021;70:240–4.
doi: 10.15585/mmwr.mm7007a3
Centers for Medicare & Medicaid Services. Telemedicine health care provider fact sheet. Baltimore, MD: US Department of Health and Human Services, Centers for Medicare & Medicaid Services; 2020. . 2020. https://www.cms.gov/newsroom/fact-sheets/medicare-telemedicine-health-care-provider-fact-sheet . Accessed 14 July 2021.
Christoforidis A, Kavoura E, Nemtsa A, Pappa K, Dimitriadou M. Coronavirus lockdown effect on type 1 diabetes management οn children wearing insulin pump equipped with continuous glucose monitoring system. Diabetes Res Clin Pract. 2020;166:108307.
pubmed: 32650036 pmcid: 7340587 doi: 10.1016/j.diabres.2020.108307
Fernández E, Cortazar A, Bellido V. Impact of covid-19 lockdown on glycemic control in patients with type 1 diabetes. Diabetes Res Clin Pract. 2020;166:108348.
pubmed: 32711000 pmcid: 7375311 doi: 10.1016/j.diabres.2020.108348
Cotovad-Bellas L, Tejera-Pérez C, Prieto-Tenreiro A, Sánchez-Bao A, Bellido-Guerrero D. The challenge of diabetes home control in COVID-19 times: proof is in the pudding. Diabetes Res Clin Pract. 2020;168:108379.
pubmed: 32853692 pmcid: 7445133 doi: 10.1016/j.diabres.2020.108379
Caruso I, Molfetta SD, Guarini F, et al. Reduction of hypoglycaemia, lifestyle modifications and psychological distress during lockdown following SARS‐CoV‐2 outbreak in type 1 diabetes. Diabetes Metab Res Rev. 2020. https://doi.org/10.1002/dmrr.3404 .
Aragona M, Rodia C, Bertolotto A, et al. Type 1 diabetes and COVID-19: the “Lockdown effect.” Diabetes Res Clin Pract. 2020;108468. https://doi.org/10.1016/j.diabres.2020.108468 .
Di Dalmazi G, Maltoni G, Bongiorno C, et al. Comparison of the effects of lockdown due to COVID-19 on glucose patterns among children, adolescents, and adults with type 1 diabetes: CGM study. BMJ Open Diabetes Res Care. 2020;8:e001664.
pubmed: 33115820 pmcid: 7594202 doi: 10.1136/bmjdrc-2020-001664
Brener A, Mazor-Aronovitch K, Rachmiel M, et al. Lessons learned from the continuous glucose monitoring metrics in pediatric patients with type 1 diabetes under COVID-19 lockdown. Acta Diabetol. 2020;57:1511–7.
pubmed: 33026497 doi: 10.1007/s00592-020-01596-4 pmcid: 33026497
Pla B, Arranz A, Knott C, et al. Impact of COVID-19 lockdown on glycemic control in adults with type 1 diabetes mellitus. J Endocr Soc. 2020;4:bvaa149.
pubmed: 33173841 pmcid: 7641317 doi: 10.1210/jendso/bvaa149
Predieri B, Leo F, Candia F, et al. Glycemic control improvement in Italian children and adolescents with type 1 diabetes followed through telemedicine during lockdown due to the COVID-19 pandemic. Front Endocrinol. 2020;11:595735.
doi: 10.3389/fendo.2020.595735
Sanchez-Conejero MS, Amigo JG de B, Bravo MLT, Jiménez JM de N. Repercusión del confinamiento por COVID-19 sobre el control glucémico en niños y adolescentes con diabetes mellitus tipo 1. An Pediatr (Engl Ed). 2021. https://doi.org/10.1016/j.anpedi.2020.12.021 .
Marigliano M, Maffeis C. Glycemic control of children and adolescents with type 1 diabetes improved after COVID-19 lockdown in Italy. Acta Diabetol. 2021;58(5):661–4.
van der Linden J, Welsh JB, Hirsch IB, Garg SK. Real-time continuous glucose monitoring during the coronavirus disease 2019 pandemic and its impact on time in range. Diabetes Technol Ther. 2021;23:S-1-S-7.
doi: 10.1089/dia.2020.0649

Auteurs

Thomas Danne (T)

Diabetes Center for Children and Adolescents, Kinder- und Jugendkrankenhaus AUF DER BULT, Janusz-Korczak-Allee 12, 30173, Hannover, Germany. danne@hka.de.

Catarina Limbert (C)

Unit for Paediatric Endocrinology and Diabetes, CHULC, Hospital Dona Estefania, Lisbon, Portugal.
NOVA Medical School, Lisbon, Portugal.

Manel Puig Domingo (M)

Endocrinology and Nutrition Service, Department of Medicine, Germans Trias i Pujol Research Institute and Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

Stefano Del Prato (S)

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

Eric Renard (E)

Department of Endocrinology, Diabetes, Nutrition, Montpellier University Hospital, Montpellier, France.
Department of Physiology, Institute of Functional Genomics, CNRS, INSERM, University of Montpellier, Montpellier, France.

Pratik Choudhary (P)

Department of Diabetes and Nutritional Sciences, King's College London, London, UK.
Diabetes Research Centre, University of Leicester, Leicester, UK.

Alexander Seibold (A)

Abbott Diabetes Care, Wiesbaden, Germany.

Classifications MeSH