Deep transcriptomic profiling of Dahl salt-sensitive rat kidneys with mutant form of Resp18.

Animals Gene Expression Profiling Kidney / metabolism Male Mutation Nerve Tissue Proteins / genetics Rats Rats, Inbred Dahl
Blood Pressure Dahl SS rat RNA Seq Renin Resp18

Journal

Biochemical and biophysical research communications
ISSN: 1090-2104
Titre abrégé: Biochem Biophys Res Commun
Pays: United States
ID NLM: 0372516

Informations de publication

Date de publication:
01 10 2021
Historique:
received: 24 06 2021
revised: 15 07 2021
accepted: 20 07 2021
pubmed: 3 8 2021
medline: 18 11 2021
entrez: 2 8 2021
Statut: ppublish

Résumé

Expression of Regulated endocrine specific protein 18 (Resp18) is localized in numerous tissues and cell types; however, its exact cellular function is unknown. We previously showed that targeted disruption of the Resp18 locus in the Dahl SS (SS) rat (Resp18

Identifiants

DOI: 10.1016/j.bbrc.2021.07.071 PMID: 34340197 PMC: PMC8528512
pubmed: 34340197
pii: S0006-291X(21)01108-6
doi: 10.1016/j.bbrc.2021.07.071
pmc: PMC8528512
mid: NIHMS1730859
pii:
doi:

Substances chimiques

Nerve Tissue Proteins 0
regulated endocrine secretory protein 18 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

35-40

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK119652
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors have no conflicts of interest to disclose.

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Auteurs

Usman M Ashraf (UM)

Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, 43614, USA.

Blair Mell (B)

Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, 43614, USA.

Pedro A Jose (PA)

Department of Medicine, Division of Kidney Diseases & Hypertension, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20052, USA; Department of Pharmacology and Physiology, The George Washington University School of Medicine & Health Sciences, Washington, DC, 20052, USA.

Sivarajan Kumarasamy (S)

Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, 43614, USA; Department of Biomedical Sciences, Ohio University, Athens, OH, 45701, USA; Diabetes Institute, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA. Electronic address: kumarasamy@ohio.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Deep transcriptomic profiling of Dahl...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › Deep transcriptomic profiling of Dahl...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Deep transcriptomic profiling of Dahl...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Deep transcriptomic profiling of Dahl...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Deep transcriptomic profiling of Dahl...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Deep transcriptomic profiling of Dahl...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Lignées consanguines de rats › Rats de lignée Dahl › Deep transcriptomic profiling of Dahl...