Rapid quantitative assays for glucose-6-phosphate dehydrogenase (G6PD) and hemoglobin combined on a capillary-driven microfluidic chip.

Antimalarials Glucosephosphate Dehydrogenase Hemoglobins Microfluidics Primaquine

Journal

Lab on a chip
ISSN: 1473-0189
Titre abrégé: Lab Chip
Pays: England
ID NLM: 101128948

Informations de publication

Date de publication:
14 09 2021
Historique:
pubmed: 4 8 2021
medline: 28 9 2021
entrez: 3 8 2021
Statut: epublish

Résumé

Rapid tests for glucose-6-phosphate dehydrogenase (G6PD) are extremely important for determining G6PD deficiency, a widespread metabolic disorder which triggers hemolytic anemia in response to primaquine and tafenoquine medication, the most effective drugs for the radical cure of malaria caused by

Identifiants

DOI: 10.1039/d1lc00354b PMID: 34341817
pubmed: 34341817
doi: 10.1039/d1lc00354b
doi:

Substances chimiques

Antimalarials 0
Hemoglobins 0
Glucosephosphate Dehydrogenase EC 1.1.1.49
Primaquine MVR3634GX1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3573-3582

Auteurs

Marco Rocca (M)

IBM Research Europe - Zurich, 8803 Rüschlikon, Switzerland. emd@zurich.ibm.com.
Institute for Biological Interfaces (IBG-1) - Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany.
ORCID: 0000-0003-3345-2794

Yuksel Temiz (Y)

IBM Research Europe - Zurich, 8803 Rüschlikon, Switzerland. emd@zurich.ibm.com.
ORCID: 0000-0001-9286-7864

Marie L Salva (ML)

IBM Research Europe - Zurich, 8803 Rüschlikon, Switzerland. emd@zurich.ibm.com.
Institute for Biological Interfaces (IBG-1) - Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany.

Samuel Castonguay (S)

Department of Engineering Physics, Polytechnique Montréal, Montréal, Québec, Canada.

Thomas Gervais (T)

Department of Engineering Physics, Polytechnique Montréal, Montréal, Québec, Canada.
Institut du Cancer de Montréal, Montréal, Québec, Canada.
Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada.
ORCID: 0000-0002-2025-9082

Christof M Niemeyer (CM)

Institute for Biological Interfaces (IBG-1) - Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany.
ORCID: 0000-0002-8837-081X

Emmanuel Delamarche (E)

IBM Research Europe - Zurich, 8803 Rüschlikon, Switzerland. emd@zurich.ibm.com.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Antipaludiques › Rapid quantitative assays for...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › Carbohydrate dehydrogenases › Glucose 6-phosphate dehydrogenase › Rapid quantitative assays for...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Globines › Hémoglobines › Rapid quantitative assays for...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Miniaturisation › Microtechnologie › Microfluidique › Rapid quantitative assays for...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Aminoquinoléines › Primaquine › Rapid quantitative assays for...