Molecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice.

colitis inflammation molecular hydrogen oxidative stress sulfasalazine

Journal

EXCLI journal
ISSN: 1611-2156
Titre abrégé: EXCLI J
Pays: Germany
ID NLM: 101299402

Informations de publication

Date de publication:
2021
Historique:
received: 14 04 2021
accepted: 15 06 2021
entrez: 4 8 2021
pubmed: 5 8 2021
medline: 5 8 2021
Statut: epublish

Résumé

Colitis is an inflammatory condition of the bowels associated with abdominal pain, diarrhea, fatigue, and fever. Its etiology is multifactorial but related to the overproduction of inflammatory and oxidative mediators. There is currently no cure for this disease, and drugs used to manage it often have deleterious side effects. H

Identifiants

pubmed: 34345230
doi: 10.17179/excli2021-3762
pii: 2021-3762
pmc: PMC8326503
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1106-1117

Informations de copyright

Copyright © 2021 LeBaron et al.

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Auteurs

Tyler W LeBaron (TW)

Centre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences, Faculty of Natural Sciences of Comenius University, 841 04 Bratislava, Slovak Republic.
Molecular Hydrogen Institute, Utah, USA.
Department of Kinesiology and Outdoor Recreation, Southern Utah University, Cedar City, 84720, Utah, USA.

Fereshteh Asgharzadeh (F)

Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Majid Khazei (M)

Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Branislav Kura (B)

Centre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences, Faculty of Natural Sciences of Comenius University, 841 04 Bratislava, Slovak Republic.

Alex Tarnava (A)

Drink HRW and Natural Wellness Now Health Products Inc., Unit C 60, Braid St, New Westminster, BC, Canada.

Jan Slezak (J)

Centre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences, Faculty of Natural Sciences of Comenius University, 841 04 Bratislava, Slovak Republic.

Classifications MeSH