The association between body mass index and fibromyalgia severity: data from a cross-sectional survey of 2339 patients.

BMI clinical severity fibromyalgia obesity widespread pain

Journal

Rheumatology advances in practice
ISSN: 2514-1775
Titre abrégé: Rheumatol Adv Pract
Pays: England
ID NLM: 101736676

Informations de publication

Date de publication:
2021
Historique:
received: 04 11 2020
accepted: 11 02 2021
entrez: 4 8 2021
pubmed: 5 8 2021
medline: 5 8 2021
Statut: epublish

Résumé

Various studies have shown that overweight and obesity are central features of FM, but the real impact of a high BMI on clinical severity in patients with FM is still controversial. The aim of this study was to analyse the relationships between BMI categories and measures of symptom severity and functional impairment using data from a Web-based registry of patients with FM. Adult patients with an ACR 2010/2011 diagnosis of FM underwent a complete physical examination and laboratory tests and were asked to complete a package of questionnaires covering their sociodemographic and treatment details, in addition to the following disease-specific questionnaires: the revised Fibromyalgia Impact Questionnaire (FIQR), the modified Fibromyalgia Assessment Status questionnaire (ModFAS) and the Polysymptomatic Distress Scale (PDS). A total of 2339 patients were recruited and divided into two weight categories, underweight/normal (U/N, Our findings demonstrate that O/O patients with FM are significantly more impaired than U/N patients in all the symptomatological and functional domains as measured using the FIQR, ModFAS and PDS, thus suggesting that being O/O has an additional effect on symptoms and function.

Identifiants

pubmed: 34345760
doi: 10.1093/rap/rkab015
pii: rkab015
pmc: PMC8324026
doi:

Types de publication

Journal Article

Langues

eng

Pagination

rkab015

Informations de copyright

© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology.

Références

Arch Gen Psychiatry. 2010 Mar;67(3):220-9
pubmed: 20194822
Arthritis Care Res (Hoboken). 2012 Feb;64(2):222-8
pubmed: 21972124
Clin Exp Rheumatol. 2013 Nov-Dec;31(6 Suppl 79):S41-9
pubmed: 23806265
J Clin Psychiatry. 2006 Aug;67(8):1219-25
pubmed: 16965199
Arthritis Res Ther. 2010;12(5):R189
pubmed: 20942911
Am J Prev Med. 2014 Jan;46(1):17-23
pubmed: 24355667
Nutrients. 2019 May 27;11(5):
pubmed: 31137906
Rheumatol Int. 2015 Feb;35(2):303-14
pubmed: 25080875
Front Med (Lausanne). 2020 Jul 24;7:360
pubmed: 32793613
Clin Rheumatol. 2012 Nov;31(11):1591-7
pubmed: 22948223
JAMA. 2010 Jan 20;303(3):235-41
pubmed: 20071471
J Rheumatol. 1991 May;18(5):728-33
pubmed: 1865419
Clin Rheumatol. 2009 Apr;28(4):475-8
pubmed: 19172342
Arthritis Res Ther. 2009;11(4):R125
pubmed: 19686606
Int J Environ Res Public Health. 2019 Nov 16;16(22):
pubmed: 31744126
Ann Rheum Dis. 2009 Dec;68(12):1800-4
pubmed: 19910301
Explore (NY). 2015 Jan-Feb;11(1):51-8
pubmed: 25442368
J Affect Disord. 2008 Sep;110(1-2):149-55
pubmed: 18234351
J Affect Disord. 2015 Dec 1;188:134-42
pubmed: 26363263
Pain Manag Nurs. 2013 Dec;14(4):268-276
pubmed: 24315250
Pain Med. 2010 Sep;11(9):1381-90
pubmed: 20735748
J Neurosci. 2008 May 14;28(20):5189-94
pubmed: 18480275
Arthritis Res Ther. 2013 Feb 27;15(1):R34
pubmed: 23446104
J Rheumatol. 2011 Jun;38(6):1113-22
pubmed: 21285161
Ann Clin Psychiatry. 2008 Jul-Sep;20(3):131-7
pubmed: 18633739
Scand J Rheumatol. 2002;31(1):27-31
pubmed: 11922197
J Pain. 2010 Dec;11(12):1329-37
pubmed: 20542742
J Psychosom Res. 2005 Nov;59(5):275-82
pubmed: 16253617
J Pain. 2010 Jul;11(7):628-35
pubmed: 20338816
Am J Phys Med Rehabil. 2012 Jul;91(7):574-83
pubmed: 22710880
Rheumatol Int. 2014 Mar;34(3):419-22
pubmed: 23283541
Clin Rheumatol. 2008 Dec;27(12):1543-7
pubmed: 18622575
Ann Rheum Dis. 2017 Feb;76(2):318-328
pubmed: 27377815
BMC Musculoskelet Disord. 2007 Mar 09;8:27
pubmed: 17349056
J Clin Psychiatry. 2001 Jun;62(6):486-91; quiz 492-3
pubmed: 11465534
Rheumatol Int. 2014 Jun;34(6):811-21
pubmed: 24322452
Eur J Pain. 2016 May;20(5):811-21
pubmed: 26492384
J Clin Rheumatol. 2015 Sep;21(6):289-95
pubmed: 26308348
J Pain. 2007 May;8(5):430-6
pubmed: 17337251
Clin J Pain. 2018 Jan;34(1):76-81
pubmed: 28272119
PeerJ. 2018 May 28;6:e4917
pubmed: 29868295
Obes Rev. 2011 May;12(5):e362-71
pubmed: 20673279
Prog Neuropsychopharmacol Biol Psychiatry. 2012 Apr 27;37(1):169-75
pubmed: 22326681

Auteurs

Fabiola Atzeni (F)

Rheumatology Unit, Department of Internal Medicine, University of Messina, Messina.

Alessandra Alciati (A)

Department of Clinical Neurosciences, Hermanas Hospitalarias, Villa San Benedetto Menni Hospital, Albese con Cassano, Humanitas Clinical and Research Center, Como, Milan, Rozzano.

Fausto Salaffi (F)

Rheumatology Clinic, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Jesi, Ancona.

Marco Di Carlo (M)

Rheumatology Clinic, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Jesi, Ancona.

Laura Bazzichi (L)

Rheumatology Unit, AOU Pisana, Pisa.

Marcello Govoni (M)

Rheumatology, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliera-Universitaria S. Anna di Ferrara.

Giovanni Biasi (G)

Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena.

Manuela Di Franco (M)

Rheumatology Unit, Department of Internal Medicine, Anesthesiological and Cardiovascular Sciences, Policlinico Umberto I, Sapienza University of Rome.

Flavio Mozzani (F)

Internal Medicine and Rheumatology Unit, Azienda Ospedaliero-Universitaria di Parma, Parma.

Elisa Gremese (E)

Rheumatology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome.

Lorenzo Dagna (L)

Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan.

Alberto Batticciotto (A)

Rheumatology Unit, Internal Medicine Department, ASST Settelaghi, Varese.

Fabio Fischetti (F)

Unit of Rheumatology, Department of Medical, Surgery and Health Sciences, ASUGI and Clinical University, University of Trieste.

Roberto Giacomelli (R)

Clinical Unit of Rheumatology, School of Medicine, University of L'Aquila.

Serena Guiducci (S)

Division of Rheumatology AOUC, Department of Experimental and Clinical Medicine, University of Florence, Florence.

Giuliana Guggino (G)

Department of Health Promotion Sciences, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo.

Mario Bentivegna (M)

Integrated Reference Center of Rheumatology, Scicli Hospital, Ragusa.

Roberto Gerli (R)

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia.

Carlo Salvarani (C)

University of Modena and Reggio Emilia, Azienda USL-IRCCS di Reggio Emilia.

Gianluigi Bajocchi (G)

Rheumatology Unit, S. Maria Hospital-USL, IRCCS Institute, Reggio Emilia.

Marco Ghini (M)

Rheumatology Unit, Azienda USL di Modena.

Florenzo Iannone (F)

Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, Bari.

Valeria Giorgi (V)

Rheumatology Unit, Internal Medicine Department, ASST Fatebenefratelli-Sacco, Milan University School of Medicine, Milan.

Sonia Farah (S)

Rheumatology Clinic, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Jesi, Ancona.

Sara Bonazza (S)

Rheumatology, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliera-Universitaria S. Anna di Ferrara.

Stefano Barbagli (S)

Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena.

Chiara Gioia (C)

Rheumatology Unit, Department of Internal Medicine, Anesthesiological and Cardiovascular Sciences, Policlinico Umberto I, Sapienza University of Rome.

Noemi Giuliana Marino (NG)

Internal Medicine and Rheumatology Unit, Azienda Ospedaliero-Universitaria di Parma, Parma.

Annunziata Capacci (A)

Rheumatology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome.

Giulio Cavalli (G)

Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan.

Antonella Cappelli (A)

Rheumatology Unit, Internal Medicine Department, ASST Settelaghi, Varese.

Francesco Carubbi (F)

Clinical Unit of Rheumatology, School of Medicine, University of L'Aquila.

Francesca Nacci (F)

Division of Rheumatology AOUC, Department of Experimental and Clinical Medicine, University of Florence, Florence.

Ilenia Riccucci (I)

Rheumatology Unit, Department of Medicine, University of Perugia, Perugia.

Maurizio Cutolo (M)

Research Laboratory and Division of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, IRCCS San Martino, Genova.

Luigi Sinigaglia (L)

Division of Rheumatology, ASST Gaetano Pini-CTO, Milano, Italy.

Piercarlo Sarzi-Puttini (P)

Rheumatology Unit, Internal Medicine Department, ASST Fatebenefratelli-Sacco, Milan University School of Medicine, Milan.

Classifications MeSH