Skin Metagenomic Sequence Analysis of Early Candida auris Outbreaks in U.S. Nursing Homes.
Candida auris
ITS1
fungal pathogen
medical mycology
mycobiome
Journal
mSphere
ISSN: 2379-5042
Titre abrégé: mSphere
Pays: United States
ID NLM: 101674533
Informations de publication
Date de publication:
25 08 2021
25 08 2021
Historique:
pubmed:
5
8
2021
medline:
14
1
2022
entrez:
4
8
2021
Statut:
ppublish
Résumé
Candida auris is a human fungal pathogen classified as an urgent threat to the delivery of health care due to its extensive antimicrobial resistance and the high mortality rates associated with invasive infections. Global outbreaks have occurred in health care facilities, particularly, long-term care hospitals and nursing homes. Skin is the primary site of colonization for C. auris. To accelerate research studies, we developed microbiome sequencing protocols, including amplicon and metagenomic sequencing, directly from patient samples at health care facilities with ongoing C. auris outbreaks. We characterized the skin mycobiome with a database optimized to classify
Identifiants
pubmed: 34346704
doi: 10.1128/mSphere.00287-21
pmc: PMC8386442
doi:
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0028721Commentaires et corrections
Type : CommentIn
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