Rosacea: An Update in Diagnosis, Classification and Management.
alpha-adrenergic agonist
anti-parasitic
antibiotic
diagnosis
dicarboxylic acid
erythema
laser therapy
management
phenotype approach
phyma
retinoids
rosacea
telangiectasia
Journal
Skin therapy letter
ISSN: 1201-5989
Titre abrégé: Skin Therapy Lett
Pays: Canada
ID NLM: 9891441
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
entrez:
4
8
2021
pubmed:
5
8
2021
medline:
29
10
2021
Statut:
ppublish
Résumé
The diagnosis and classification of rosacea has been modified to reflect presenting features. On exclusion of differentials, the diagnosis of rosacea is based on the presence of either (1) phymatous changes, or (2) centrofacial persistent erythema. In their absence, diagnosis can be established by presence of any two of: flushing/transient erythema, papules and pustules, telangiectases, or ocular manifestations. Management of rosacea depends on presenting feature(s), their severity, and impact. General management includes gentle skin care, sun protection, and trigger avoidance. Evidence-based treatment recommendations include topical brimonidine and oxymetazoline for persistent erythema; topical azelaic acid, ivermectin, metronidazole, minocycline and oral doxycycline, tetracycline and isotretinoin for papules and pustules; vascular lasers and light devices for telangiectases; and omega-3 fatty acids and cyclosporine ophthalmic emulsion for ocular rosacea. While surgical or laser therapy can be considered for clinically noninflamed phyma, there are no trials on their utility. Combination therapies include topical brimonidine with topical ivermectin, or topical metronidazole with oral doxycycline. Topical metronidazole, topical ivermectin, and topical azelaic acid are appropriate for maintenance therapy. In conclusion, the updated phenotype approach, based on presenting clinical features, is the foundation for current diagnosis, classification, and treatment of rosacea.
Substances chimiques
Dermatologic Agents
0
Metronidazole
140QMO216E
Brimonidine Tartrate
4S9CL2DY2H
Doxycycline
N12000U13O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-8Déclaration de conflit d'intérêts
Cindy Kang and Monica Shah have no conflicts of interest to disclose. Jerry Tan has been a consultant, investigator and/or speaker for Almirall, Bausch, Boots/Walgreens, Cipher, Galderma, L’Oréal, Promius, Sun and Vichy. Disclaimers: This manuscript is an original submission. Views expressed in the submitted article are our own and not official positions of our institutions.