Current and emerging strategies to combat antimalarial resistance.

Since the spread of chloroquine resistance in We reviewed past recommendations and activities to respond to resistance as well as ongoing research into new ways to stop or delay the spread of resistant parasites. Inadequate information limits the options and support for a strong, coordinated response to artemisinin partial resistance in Africa, making better phenotypic and genotypic surveillance a priority. A response to resistance needs to address factors that may have hastened the emergence and could speed the spread, including overuse of drugs and lack of access to quality treatment. New ways to use the existing treatments in response to resistance, such as multiple first-lines, are currently impeded by the limited number of drugs available.