Prevalence of strongyloidiasis in Peru: systematic review and meta-analysis.


Journal

BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551

Informations de publication

Date de publication:
04 Aug 2021
Historique:
received: 04 01 2021
accepted: 16 07 2021
entrez: 5 8 2021
pubmed: 6 8 2021
medline: 25 9 2021
Statut: epublish

Résumé

Strongyloidiasis is a disease of great public health significance, caused by the parasitic nematodes Strongyloides stercoralis, Strongyloides fuelleborni, and Strongyloides fuelleborni subsp. kellyi. This systematic review and meta-analysis aimed to assess the prevalence of Strongyloides stercoralis infection in Peru. The review was based on a literature search in PubMed, SciELO and Google Scholar using the key words or root words "strongyl*" AND "Peru" on 15 July 2020. Eligible studies were published from 1 January 1981 to 15 July 2020 and written in English, Spanish, Italian, or French. We included 21 papers in the analysis. Studies were heterogeneous in terms of study population and diagnostic methods (e.g. Baermann technique, agar, Dancescu or charcoal cultures, serology, string capsule). Prevalence of S. stercoralis ranged from 0.3 to 45%. The pooled proportion of Strongyloides in the general population was 7.34% (95% CI 4.97 to 10.13%). Half the studies were designed to detect parasites in general. In studies designed to detect S. stercoralis, the most widely used diagnostic method was the Baermann technique. Prevalence of S. stercoralis in Peru was high but varied by geographic area, techniques for stool examination, and participant characteristics.

Sections du résumé

BACKGROUND BACKGROUND
Strongyloidiasis is a disease of great public health significance, caused by the parasitic nematodes Strongyloides stercoralis, Strongyloides fuelleborni, and Strongyloides fuelleborni subsp. kellyi. This systematic review and meta-analysis aimed to assess the prevalence of Strongyloides stercoralis infection in Peru.
METHODS METHODS
The review was based on a literature search in PubMed, SciELO and Google Scholar using the key words or root words "strongyl*" AND "Peru" on 15 July 2020. Eligible studies were published from 1 January 1981 to 15 July 2020 and written in English, Spanish, Italian, or French.
RESULTS RESULTS
We included 21 papers in the analysis. Studies were heterogeneous in terms of study population and diagnostic methods (e.g. Baermann technique, agar, Dancescu or charcoal cultures, serology, string capsule). Prevalence of S. stercoralis ranged from 0.3 to 45%. The pooled proportion of Strongyloides in the general population was 7.34% (95% CI 4.97 to 10.13%). Half the studies were designed to detect parasites in general. In studies designed to detect S. stercoralis, the most widely used diagnostic method was the Baermann technique.
CONCLUSION CONCLUSIONS
Prevalence of S. stercoralis in Peru was high but varied by geographic area, techniques for stool examination, and participant characteristics.

Identifiants

pubmed: 34348671
doi: 10.1186/s12879-021-06441-9
pii: 10.1186/s12879-021-06441-9
pmc: PMC8336367
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

755

Subventions

Organisme : University Development Cooperation Program, Miguel Hernández University of Elche and Generalitat Valenciana.
ID : SOLCIF/2017/0005

Informations de copyright

© 2021. The Author(s).

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Auteurs

Sonia Ortiz-Martínez (S)

Medical Practice El Ballestero, Health Service of Castilla La Mancha, Albacete, Spain.

José-Manuel Ramos-Rincón (JM)

Clinical Medicine Department, University Miguel Hernández of Elche, Ctra N-332, 03550 Sant Joan d'Alacant, Alicante, Spain. jramosrincon@yahoo.es.
Internal Medicine Service, General University Hospital of Alicante-ISABIAL, Alicante, Spain. jramosrincon@yahoo.es.

María-Esteyner Vásquez-Chasnamote (ME)

Natural Resources Research Center. National University of the Peruvian Amazon, Iquitos, Peru.

Olga-Nohelia Gamboa-Paredes (ON)

Research Assistant. Amazon Rainforest Civil Association, Iquitos, Peru.

Katty-Madeleine Arista-Flores (KM)

Research Assistant. Amazon Rainforest Civil Association, Iquitos, Peru.

Luis-Alfredo Espinoza-Venegas (LA)

Infectious Diseases and Tropical Medicine Service, Loreto Regional Hospital, Iquitos, Peru.

Eva de-Miguel-Balsa (E)

Clinical Medicine Department, University Miguel Hernández of Elche, Ctra N-332, 03550 Sant Joan d'Alacant, Alicante, Spain.
Intensive Care Unit, General University Hospital of Elche, Alicante, Spain.

Viviana-Vanessa Pinedo-Cancino (VV)

Molecular Biology and Immunology Laboratory of the Specialized Unit of LIPNAA-CIRNA, National University of the Peruvian Amazon, Iquitos, Peru.

Miguel Górgolas-Hernández-Mora (M)

Infectious Disease Division, University Hospital Foundation Jiménez Díaz, Madrid, Spain.
Medicine Department, Autonomous University of Madrid, Madrid, Spain.

Martín Casapía-Morales (M)

Infectious Diseases and Tropical Medicine Service, Loreto Regional Hospital, Iquitos, Peru.
Medical Department, Amazon Rainforest Civil Association, Iquitos, Peru.
School of Medicine, National University of the Peruvian Amazon, Iquitos, Peru.

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