A rare case of antibody against enhancement media interfering with crossmatching: A case report and review of literature.
Enhancement media
low-ionic strength solution
pretransfusion testing
Journal
Asian journal of transfusion science
ISSN: 0973-6247
Titre abrégé: Asian J Transfus Sci
Pays: India
ID NLM: 101306858
Informations de publication
Date de publication:
Historique:
received:
19
06
2020
revised:
09
08
2020
accepted:
30
08
2020
entrez:
5
8
2021
pubmed:
6
8
2021
medline:
6
8
2021
Statut:
ppublish
Résumé
Detection of clinically significant alloantibodies during pretransfusion testing is essential before any blood transfusion. Sometimes, clinically insignificant antibodies unrelated to blood group antigen may interfere with routine testing. Their interpretation is often made only after tedious immunohematology workup resulting in the exclusion of all possible clinically significant antibodies. We encountered such incidence which interfered with crossmatching. In our case, direct antiglobulin test was negative, indirect antiglobulin test and autocontrol were positive with pan-reactive antibody screening test, and group-specific units were incompatible. After meticulous workup, we could find that these antibodies were directed against the enhancement media, low-ionic strength solution in this case.
Identifiants
pubmed: 34349467
doi: 10.4103/ajts.AJTS_99_20
pii: AJTS-15-100
pmc: PMC8294438
doi:
Types de publication
Case Reports
Langues
eng
Pagination
100-103Informations de copyright
Copyright: © 2021 Asian Journal of Transfusion Science.
Déclaration de conflit d'intérêts
There are no conflicts of interest.
Références
Transfusion. 1984 Jul-Aug;24(4):365-7
pubmed: 6464162
Am J Med Technol. 1976 Jun;42(6):209-19
pubmed: 779471
Transfusion. 1982 Jan-Feb;22(1):31-5
pubmed: 7064203
Transfusion. 1993 Aug;33(8):686-8
pubmed: 8342238
Vox Sang. 1974;26(1):53-61
pubmed: 4420622
Asian J Transfus Sci. 2019 Jul-Dec;13(2):115-119
pubmed: 31896918
Am J Clin Pathol. 1987 May;87(5):633-5
pubmed: 3578138
Immunohematology. 1995;11(1):18-9
pubmed: 15447074
Transfusion. 2012 Apr;52(4):844-8
pubmed: 21910740
Immunohematology. 2019 Sep;35(3):95-101
pubmed: 31621367
Immunohematology. 2016 Sep;32(3):96-99
pubmed: 27834481
Transfusion. 1980 Mar-Apr;20(2):206-11
pubmed: 6768173
Asian J Transfus Sci. 2018 Jul-Dec;12(2):169-172
pubmed: 30692805