Evaluation of the Relationship Between Transcutaneous Bilirubin Measurement and Total Serum Bilirubin in Neonatal Patients Followed for Jaundice.
Jaundice
neonate
serum bilirubin
trancutaneous bilirubin
Journal
Sisli Etfal Hastanesi tip bulteni
ISSN: 1302-7123
Titre abrégé: Sisli Etfal Hastan Tip Bul
Pays: Turkey
ID NLM: 9424130
Informations de publication
Date de publication:
2021
2021
Historique:
received:
08
01
2020
accepted:
13
04
2020
entrez:
5
8
2021
pubmed:
6
8
2021
medline:
6
8
2021
Statut:
epublish
Résumé
Jaundice is a physiological condition caused by hyperbilirubinemia, which is common in neonatal period. However, severe hyperbilirubinemia can cause kernicterus, which is a serious condition that leads to neurological problems. In this study, we aimed to investigate whether it is safe to use transcutaneous bilirubin (TcB) instead of blood for the evaluation of jaundice by comparing TcB measurement with standard total serum bilirubin (TSB) measurement values. A total of 105 term and early term infants with gestational ages between 37 and 42 weeks were included in the study. MBJ20 TcB measuring device was used for TcB measurement. TcB was measured from the forehead and sternum. To evaluate the relationship between TcB measurements and TSB measurements, we performed Pearson correlation, Spearman correlation, linear regression analysis, and Bland-Altman analysis in which we evaluated the scatter plot of the differences between the average values of the measurements. There was a positive and statistically significant correlation between TcB forehead and TSB measurements and TcB sternum and TSB measurements (p<0.001). Linear regression analysis showed a positive directional correlation between TcB forehead and TSB measurements (R²=0.85) and TcB sternum and TSB measurements (R²=0.87). Bland-Altman analysis showed a good consistency between TSB and TcB forehead measurement methods (mean difference: 0.39±1.46, 95% CI: [-2.47]-[3.26]), and between TSB and TcB sternum measurement methods (mean difference: 0.49±1.32 95% CI: [-2.1]-[3.07]). As a result of our study, we found that TcB measurement can be reliable instead of taking blood for jaundice evaluation.
Identifiants
pubmed: 34349605
doi: 10.14744/SEMB.2020.79837
pii: MBSEH-55-262
pmc: PMC8298076
doi:
Types de publication
Journal Article
Langues
eng
Pagination
262-267Informations de copyright
Copyright: © 2021 by The Medical Bulletin of Sisli Etfal Hospital.
Déclaration de conflit d'intérêts
Conflict of Interest: The authors have no conflict of interest.
Références
J Perinatol. 2011 Sep;31(9):621-4
pubmed: 21293381
Pediatrics. 2006 May;117(5):e855-62
pubmed: 16651290
BMJ Paediatr Open. 2017 Aug 31;1(1):e000065
pubmed: 29637112
Afr J Prim Health Care Fam Med. 2018 Apr 12;10(1):e1-e6
pubmed: 29781686
Int J Pediatr. 2019 Jan 1;2019:3812152
pubmed: 30713561
CMAJ Open. 2018 Jul 27;6(3):E285-E291
pubmed: 30054296
J Pediatr. 2019 May;208:273-278.e1
pubmed: 30853197
Pediatrics. 2004 Jul;114(1):297-316
pubmed: 15231951
Arch Dis Child Fetal Neonatal Ed. 2006 Nov;91(6):F434-8
pubmed: 16849367
Oman Med J. 2019 Jan;34(1):26-33
pubmed: 30671181
Arch Dis Child Fetal Neonatal Ed. 2019 Mar;104(2):F202-F204
pubmed: 29802103
Acta Paediatr. 2003 May;92(5):577-81
pubmed: 12839288
Pediatrics. 2001 Jun;107(6):1264-71
pubmed: 11389241
J Perinatol. 2016 Oct;36(10):858-61
pubmed: 27279078
Acta Paediatr. 2003;92(3):327-31
pubmed: 12725548
Int J Pediatr. 2018 Mar 20;2018:4856390
pubmed: 29755532
Pediatr Neonatol. 2010 Jun;51(3):143-8
pubmed: 20675237
Pediatrics. 2009 Oct;124(4):1031-9
pubmed: 19786442
Clin Chem. 2005 Mar;51(3):540-4
pubmed: 15738516