Quantitative Relationships Between Growth, Differentiation, and Shape That Control

IbM computational model computer simulation drosophila evolution eye development mathematical modeling organ growth size

Journal

Frontiers in cell and developmental biology
ISSN: 2296-634X
Titre abrégé: Front Cell Dev Biol
Pays: Switzerland
ID NLM: 101630250

Informations de publication

Date de publication:
2021
Historique:
received: 17 03 2021
accepted: 24 06 2021
entrez: 5 8 2021
pubmed: 6 8 2021
medline: 6 8 2021
Statut: epublish

Résumé

The size of organs is critical for their function and often a defining trait of a species. Still, how organs reach a species-specific size or how this size varies during evolution are problems not yet solved. Here, we have investigated the conditions that ensure growth termination, variation of final size and the stability of the process for developmental systems that grow and differentiate simultaneously. Specifically, we present a theoretical model for the development of the

Identifiants

pubmed: 34350178
doi: 10.3389/fcell.2021.681933
pmc: PMC8326509
doi:

Types de publication

Journal Article

Langues

eng

Pagination

681933

Informations de copyright

Copyright © 2021 Lobo-Cabrera, Navarro, Iannini, Casares and Cuetos.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Francisco Javier Lobo-Cabrera (FJ)

Department of Physical, Chemical and Natural Systems, Pablo de Olavide University, Sevilla, Spain.

Tomás Navarro (T)

DMC2-GEM Unit, The CABD, CSIC-Pablo de Olavide University-JA, Seville, Spain.

Antonella Iannini (A)

DMC2-GEM Unit, The CABD, CSIC-Pablo de Olavide University-JA, Seville, Spain.

Fernando Casares (F)

DMC2-GEM Unit, The CABD, CSIC-Pablo de Olavide University-JA, Seville, Spain.

Alejandro Cuetos (A)

Department of Physical, Chemical and Natural Systems, Pablo de Olavide University, Sevilla, Spain.

Classifications MeSH