Spatial Distribution of a Porphyrin-Based Photosensitizer Reveals Mechanism of Photodynamic Inactivation of

Candida albicans antifungal microscopy photodynamic porphyrin

Journal

Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047

Informations de publication

Date de publication:
2021
Historique:
received: 22 12 2020
accepted: 07 06 2021
entrez: 5 8 2021
pubmed: 6 8 2021
medline: 6 8 2021
Statut: epublish

Résumé

The antimicrobial photodynamic therapy (aPDT) is a promising approach for the control of microbial and especially fungal infections such as mucosal mycosis. TMPyP [5,10,15, 20-tetrakis(1-methylpyridinium-4-yl)-porphyrin tetra p-toluenesulfonate] is an effective photosensitizer (PS) that is commonly used in aPDT. The aim of this study was to examine the localization of TMPyP in

Identifiants

pubmed: 34350191
doi: 10.3389/fmed.2021.641244
pmc: PMC8326406
doi:

Types de publication

Journal Article

Langues

eng

Pagination

641244

Informations de copyright

Copyright © 2021 Voit, Cieplik, Regensburger, Hiller, Gollmer, Buchalla and Maisch.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Thomas Voit (T)

Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.
Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.
Private Practice, Kaufbeuren, Germany.

Fabian Cieplik (F)

Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.

Johannes Regensburger (J)

Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.

Karl-Anton Hiller (KA)

Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.

Anita Gollmer (A)

Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.

Wolfgang Buchalla (W)

Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regensburg, Germany.

Tim Maisch (T)

Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.

Classifications MeSH