A review of gliomas-related proteins. Characteristics of potential biomarkers.

GBM biochemistry biomarkers glioma proteomics

Journal

American journal of cancer research
ISSN: 2156-6976
Titre abrégé: Am J Cancer Res
Pays: United States
ID NLM: 101549944

Informations de publication

Date de publication:
2021
Historique:
received: 13 04 2021
accepted: 15 05 2021
entrez: 6 8 2021
pubmed: 7 8 2021
medline: 7 8 2021
Statut: epublish

Résumé

Brain tumors are one of the most commonly diagnosed cancers of the central nervous system. Of all diagnosed malignant tumors, 80% are gliomas. An unequivocal diagnosis of gliomas is not always simple, and there is a great need for research to find new treatment options and diagnostic approaches. This paper is focused on the glioma-related protein profiles as compared to healthy brain tissue, which is reflected in multiple correlations between biological aspects that influence proliferation, apoptosis evasion and the invasiveness of neoplastic cells. The work presents the possibilities of facilitating clinical practice with proteomic biomarkers, which offer a wider diagnostic spectrum and reduce the margin of mistake in histopathological or imaging diagnostic methods. In fact, many changes in the body's homeostasis can be overlooked due to the lack of symptoms or their non-specificity. Nevertheless, a single marker has limited reliability in distinguishing a particular tumor subtype, since the increased or decreased level of the protein of interest may differ between the stages or locations of the tumor. Moreover, the correlations between proposed proteins - presented in this paper - may help clinicians to choose the most optimal therapy, and estimate its effectiveness, or indicate new therapeutic targets affecting disrupted biochemical pathways.

Identifiants

pubmed: 34354853
pmc: PMC8332856

Types de publication

Journal Article Review

Langues

eng

Pagination

3425-3444

Informations de copyright

AJCR Copyright © 2021.

Déclaration de conflit d'intérêts

None.

Références

J Clin Invest. 1990 Jul;86(1):131-40
pubmed: 2164040
Adv Exp Med Biol. 2020;1202:129-149
pubmed: 32034712
Acta Neuropathol. 2002 Feb;103(2):171-8
pubmed: 11810184
Int J Clin Exp Pathol. 2019 Feb 01;12(2):539-548
pubmed: 31933858
Brain Pathol. 2008 Jul;18(3):378-86
pubmed: 18394009
Br J Cancer. 2009 Sep 15;101(6):973-82
pubmed: 19707201
Neurosurgery. 2008 Sep;63(3):560-9; discussion 569-70
pubmed: 18812968
BMC Dev Biol. 2001;1:5
pubmed: 11305929
Urol Int. 2017;99(2):237-244
pubmed: 27027898
Oncotarget. 2017 Mar 21;8(12):20354-20361
pubmed: 27888628
Oncogene. 2006 Mar 16;25(12):1721-32
pubmed: 16288224
J Cell Mol Med. 2014 Jun;18(6):947-61
pubmed: 24712303
Sci Rep. 2018 Feb 14;8(1):2982
pubmed: 29445239
Oncol Lett. 2018 Apr;15(4):5131-5136
pubmed: 29552147
Nat Rev Immunol. 2002 Aug;2(8):569-79
pubmed: 12154376
Cancer Res. 1999 Jan 15;59(2):442-9
pubmed: 9927060
Endocr Relat Cancer. 2004 Dec;11(4):843-54
pubmed: 15613457
Acta Neuropathol. 2011 Oct;122(4):495-510
pubmed: 21863242
Exp Hematol Oncol. 2013 Jul 01;2(1):17
pubmed: 23815814
Neuro Oncol. 2011 Nov;13(11):1244-51
pubmed: 21831900
Oncotarget. 2016 Dec 13;7(50):83701-83719
pubmed: 27863376
Am J Physiol Cell Physiol. 2017 Nov 1;313(5):C584-C592
pubmed: 28978524
BMC Cancer. 2011 Apr 02;11:120
pubmed: 21457573
Cell Death Differ. 2012 Jan;19(1):180-3
pubmed: 22095277
Semin Cancer Biol. 2006 Aug;16(4):318-30
pubmed: 16934487
Phytomedicine. 2001 Nov;8(6):492-4
pubmed: 11824528
CNS Neurosci Ther. 2014 Feb;20(2):112-8
pubmed: 24279471
EMBO J. 2001 Oct 15;20(20):5568-77
pubmed: 11598000
Front Endocrinol (Lausanne). 2020 Jul 31;11:485
pubmed: 32849278
Leukemia. 2015 Jan;29(1):169-76
pubmed: 24912431
Nutr Cancer. 2000;38(1):40-9
pubmed: 11341043
Proteome Sci. 2014 Sep 24;12(1):47
pubmed: 25298751
Hum Mol Genet. 2011 Jun 1;20(11):2195-203
pubmed: 21421568
Oncol Lett. 2019 Jul;18(1):359-367
pubmed: 31289507
Tumour Biol. 2013 Jun;34(3):1523-30
pubmed: 23404405
Int J Mol Sci. 2017 Jul 14;18(7):
pubmed: 28708099
Int J Mol Sci. 2020 Jan 30;21(3):
pubmed: 32019108
Tumour Biol. 2013 Aug;34(4):2283-92
pubmed: 23589055
ScientificWorldJournal. 2014 Mar 05;2014:605236
pubmed: 24741354
Acta Neuropathol. 2012 Nov;124(5):615-25
pubmed: 22886134
PLoS One. 2016 Feb 12;11(2):e0149361
pubmed: 26871431
Br J Cancer. 2013 Nov 26;109(11):2853-63
pubmed: 24169356
FEBS J. 2012 Oct;279(20):3898-910
pubmed: 22897481
Neuro Oncol. 2016 Sep;18(9):1253-64
pubmed: 27006175
Nat Rev Cancer. 2004 Jul;4(7):528-39
pubmed: 15229478
Am J Pathol. 2002 Feb;160(2):693-700
pubmed: 11839590
Oncogene. 2005 May 19;24(22):3606-18
pubmed: 15750632
Glia. 2003 Apr 15;42(2):194-208
pubmed: 12655603
J Biol Chem. 1991 Jul 15;266(20):13462-7
pubmed: 2071612
Cancer Res. 2002 Feb 15;62(4):1103-9
pubmed: 11861389
Future Oncol. 2009 Sep;5(7):1065-82
pubmed: 19792974
J Exp Med. 2011 Dec 19;208(13):2657-73
pubmed: 22162832
Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):9064-9073
pubmed: 32273388
Exp Cell Res. 2020 Apr 1;389(1):111893
pubmed: 32035133
Cancer Res. 2005 Jun 15;65(12):5190-4
pubmed: 15958563
Cancers (Basel). 2021 Mar 01;13(5):
pubmed: 33804433
Cancer Res. 1992 Jun 15;52(12):3372-7
pubmed: 1596895
J Neuropathol Exp Neurol. 2000 Jun;59(6):495-503
pubmed: 10850862
Gene. 2013 May 1;519(2):266-70
pubmed: 23462332
PLoS One. 2008;3(11):e3769
pubmed: 19020659
Nat Genet. 2012 Jan 29;44(3):251-3
pubmed: 22286216
Nat Rev Cancer. 2003 Jul;3(7):489-501
pubmed: 12835669
Cancer Res. 2007 Aug 1;67(15):7335-42
pubmed: 17671203
Prostate. 1999 Jun 1;39(4):298-304
pubmed: 10344220
J Pathol. 2012 Jan;226(1):7-16
pubmed: 22072542
Anticancer Res. 1992 Jan-Feb;12(1):235-40
pubmed: 1567172
Genes Dev. 2007 Nov 1;21(21):2683-710
pubmed: 17974913
Cureus. 2018 Oct 11;10(10):e3439
pubmed: 30555755
Cancer Med. 2016 Dec;5(12):3532-3543
pubmed: 27882696
Biochim Biophys Acta. 2013 Dec;1836(2):245-54
pubmed: 23891969
Oncotarget. 2015 Mar 20;6(8):6267-80
pubmed: 25749043
Cancer Lett. 2012 Jun 28;319(2):164-172
pubmed: 22261339
Am J Surg Pathol. 2014 Nov;38(11):1571-6
pubmed: 25007147
BMC Cancer. 2017 Dec 28;17(1):889
pubmed: 29282022
Cell. 1990 Jun 29;61(7):1303-13
pubmed: 1694723
J Cancer. 2018 Oct 31;9(23):4496-4502
pubmed: 30519355
Curr Opin Cell Biol. 2015 Feb;32:121-30
pubmed: 25726916
Science. 2011 Sep 9;333(6048):1453-5
pubmed: 21817013
Sci Rep. 2019 Feb 26;9(1):2749
pubmed: 30808902
Annu Rev Physiol. 2011;73:479-501
pubmed: 21054166
Expert Rev Mol Diagn. 2009 Oct;9(7):709-20
pubmed: 19817555
Nat Commun. 2019 Feb 8;10(1):661
pubmed: 30737375
Lab Invest. 2006 Dec;86(12):1221-32
pubmed: 17075581
Neuro Oncol. 2019 Nov 1;21(Suppl 5):v1-v100
pubmed: 31675094
Chin J Cancer. 2011 Sep;30(9):590-602
pubmed: 21880180
Cell. 2009 Dec 24;139(7):1327-41
pubmed: 20064378
Genome Res. 2010 Mar;20(3):351-60
pubmed: 20110566
Cells. 2020 Mar 13;9(3):
pubmed: 32183030
Oncol Rep. 2019 Jul;42(1):399-413
pubmed: 31115554
Neurosurgery. 1991 Feb;28(2):216-22
pubmed: 1997889
Tumour Biol. 2013 Feb;34(1):25-31
pubmed: 22961700
J Cell Sci. 2014 Jun 15;127(Pt 12):2647-58
pubmed: 24762811
Nat Genet. 1993 May;4(1):42-6
pubmed: 8099841
N Engl J Med. 2008 Jul 31;359(5):492-507
pubmed: 18669428
Nat Struct Mol Biol. 2011 Jun 12;18(7):769-76
pubmed: 21666679
AJNR Am J Neuroradiol. 2012 May;33(5):852-7
pubmed: 22268087
J Pathol. 1996 Jan;178(1):48-52
pubmed: 8778315
Cell. 1996 May 31;85(5):683-93
pubmed: 8646777
PLoS One. 2017 Feb 27;12(2):e0172791
pubmed: 28241049
Mol Cell Proteomics. 2012 Dec;11(12):1724-40
pubmed: 22964225
J Neurooncol. 2008 Jul;88(3):261-72
pubmed: 18398576
Mol Cell Proteomics. 2012 Jun;11(6):M111.013565
pubmed: 22219345
Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14075-80
pubmed: 20651253
Cancer Commun (Lond). 2020 Oct;40(10):518-530
pubmed: 32888253
Genes Dev. 2001 Jun 1;15(11):1311-33
pubmed: 11390353
Proc Natl Acad Sci U S A. 1988 Oct;85(20):7748-52
pubmed: 2845420
J Clin Invest. 2003 Aug;112(3):357-66
pubmed: 12897203
Tumour Biol. 2011 Jun;32(3):441-50
pubmed: 21153724
Biomedicines. 2020 Aug 27;8(9):
pubmed: 32867190
J Neurooncol. 2013 Nov;115(2):249-59
pubmed: 23934175
Nat Med. 2004 Nov;10(11):1257-60
pubmed: 15502845
Cancer Sci. 2017 Dec;108(12):2319-2325
pubmed: 28985030
Nat Med. 2007 Jan;13(1):84-8
pubmed: 17159987
PLoS One. 2012;7(9):e46153
pubmed: 23029420
Expert Rev Mol Diagn. 2014 May;14(4):439-52
pubmed: 24746164
J Clin Oncol. 2007 Jun 1;25(16):2288-94
pubmed: 17538175
Acc Chem Res. 2011 Mar 15;44(3):171-9
pubmed: 21314091
Nature. 2012 Jan 29;482(7384):226-31
pubmed: 22286061
Clin Cancer Res. 1999 Mar;5(3):559-67
pubmed: 10100707
Mol Neurobiol. 2020 May;57(5):2461-2478
pubmed: 32152825
Cancers (Basel). 2018 Sep 01;10(9):
pubmed: 30200436
Acta Neuropathol. 2005 Sep;110(3):239-46
pubmed: 16133547
Trends Neurosci. 2015 Jun;38(6):364-74
pubmed: 25975510
Am J Surg Pathol. 2017 Jul;41(7):941-949
pubmed: 28346326
Nat Commun. 2012 Mar 06;3:724
pubmed: 22395615
Can J Neurol Sci. 2016 Jul;43(4):494-502
pubmed: 27324313
Cancer Res. 2006 Sep 1;66(17):8492-500
pubmed: 16951161
Breast Cancer Res Treat. 2012 Feb;131(3):791-800
pubmed: 21452021
Cancer Lett. 2006 May 8;236(1):39-45
pubmed: 15967572
Brain Tumor Pathol. 2015 Apr;32(2):90-8
pubmed: 25178519
Acta Neuropathol. 2012 Jun;123(6):853-60
pubmed: 22588899
Cell. 2010 Mar 5;140(5):678-91
pubmed: 20211137
Oncotarget. 2012 Jul;3(7):709-22
pubmed: 22869205
Cancer Res. 1997 Oct 1;57(19):4187-90
pubmed: 9331072
Cancer Res. 1994 Dec 1;54(23):6027-31
pubmed: 7954439
Urology. 2004 Oct;64(4):839-44
pubmed: 15491744
N Engl J Med. 2015 Jun 25;372(26):2481-98
pubmed: 26061751
Br J Cancer. 1999 Jan;79(2):300-7
pubmed: 9888472
Dev Biol. 2004 Aug 1;272(1):1-14
pubmed: 15242786
Oncogene. 2004 Nov 4;23(52):8486-96
pubmed: 15378018
Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6021-6
pubmed: 23530248
Nat Commun. 2017 Dec 4;8(1):1913
pubmed: 29203859
Sci Rep. 2015 Nov 12;5:16495
pubmed: 26559910

Auteurs

Tomasz Pienkowski (T)

Clinical Research Center, Medical University of Bialystok M. Sklodowskiej-Curie 24a, 15-276 Bialystok, Poland.

Tomasz Kowalczyk (T)

Clinical Research Center, Medical University of Bialystok M. Sklodowskiej-Curie 24a, 15-276 Bialystok, Poland.

Adam Kretowski (A)

Clinical Research Center, Medical University of Bialystok M. Sklodowskiej-Curie 24a, 15-276 Bialystok, Poland.

Michal Ciborowski (M)

Clinical Research Center, Medical University of Bialystok M. Sklodowskiej-Curie 24a, 15-276 Bialystok, Poland.

Classifications MeSH