ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function.
Biological sciences
Molecular neuroscience
Neuroscience
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
23 Jul 2021
23 Jul 2021
Historique:
received:
05
09
2020
revised:
15
04
2021
accepted:
18
06
2021
entrez:
6
8
2021
pubmed:
7
8
2021
medline:
7
8
2021
Statut:
epublish
Résumé
Derlin family members (Derlins) are primarily known as components of the endoplasmic reticulum-associated degradation pathway that eliminates misfolded proteins. Here we report a function of Derlins in the brain development. Deletion of
Identifiants
pubmed: 34355142
doi: 10.1016/j.isci.2021.102758
pii: S2589-0042(21)00726-4
pmc: PMC8324814
doi:
Types de publication
Journal Article
Langues
eng
Pagination
102758Informations de copyright
© 2021 The Author(s).
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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