Synthesis and pharmacological evaluation of [
Journal
RSC medicinal chemistry
ISSN: 2632-8682
Titre abrégé: RSC Med Chem
Pays: England
ID NLM: 101759460
Informations de publication
Date de publication:
21 Jul 2021
21 Jul 2021
Historique:
received:
05
02
2021
accepted:
15
03
2021
entrez:
6
8
2021
pubmed:
7
8
2021
medline:
7
8
2021
Statut:
epublish
Résumé
Radiopharmaceuticals that target the translocator protein 18 kDa (TSPO) have been investigated with positron emission tomography (PET) to study neuroinflammation, neurodegeneration and cancer. We have developed the novel, achiral, 2-phenylimidazo[1,2-
Identifiants
pubmed: 34355185
doi: 10.1039/d1md00035g
pii: d1md00035g
pmc: PMC8292990
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1207-1221Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
J Endocrinol. 2016 Oct;231(1):R1-R30
pubmed: 27422254
Trends Pharmacol Sci. 2006 Aug;27(8):402-9
pubmed: 16822554
ChemMedChem. 2019 May 6;14(9):982-993
pubmed: 30900397
Neurochem Int. 2004 May;44(6):433-40
pubmed: 14687608
J Cereb Blood Flow Metab. 2010 Sep;30(9):1608-18
pubmed: 20424634
Mol Pharm. 2011 Jun 6;8(3):823-32
pubmed: 21417480
J Med Chem. 2006 May 4;49(9):2735-42
pubmed: 16640334
Endocrinology. 2009 Dec;150(12):5438-45
pubmed: 19846611
Cancer. 1990 Jan 1;65(1):93-7
pubmed: 2152852
Cancer Biother Radiopharm. 2013 Apr;28(3):254-9
pubmed: 23350894
Theranostics. 2014 Feb 26;4(5):546-55
pubmed: 24672585
J Nucl Med. 2008 May;49(5):814-22
pubmed: 18413395
Brain Behav Immun. 2016 May;54:149-157
pubmed: 26820224
Eur J Nucl Med Mol Imaging. 2011 Mar;38(3):509-14
pubmed: 20936410
Blood. 1996 Apr 15;87(8):3170-8
pubmed: 8605331
Nucl Med Biol. 1996 Jan;23(1):23-8
pubmed: 9004910
Bioorg Med Chem. 2006 Jun 1;14(11):3938-46
pubmed: 16480880
J Med Chem. 2004 Mar 25;47(7):1852-5
pubmed: 15027878
J Neurosci. 1984 Feb;4(2):593-603
pubmed: 6321699
J Med Chem. 2005 Jan 13;48(1):292-305
pubmed: 15634024
J Nucl Med. 2011 Jan;52(1):107-14
pubmed: 21149488
Eur J Med Chem. 2019 Aug 15;176:410-418
pubmed: 31125895
Life Sci. 1993;52(1):107-18
pubmed: 8380214
Arch Int Pharmacodyn Ther. 1983 Nov;266(1):38-49
pubmed: 6667063
J Med Chem. 1997 Sep 12;40(19):3109-18
pubmed: 9301675
Mol Imaging. 2015;14:
pubmed: 26044669
Bioorg Med Chem Lett. 2012 Feb 1;22(3):1308-13
pubmed: 22244939
Eur J Nucl Med Mol Imaging. 2008 Apr;35(4):779-89
pubmed: 18057934
J Med Chem. 2011 Jan 13;54(1):366-73
pubmed: 21133364
J Nucl Med. 2013 Aug;54(8):1320-2
pubmed: 23785173
J Nucl Med. 2017 Feb;58(2):320-325
pubmed: 27856631
Nucl Med Biol. 2003 May;30(4):435-9
pubmed: 12767401
Curr Top Med Chem. 2011;11(7):860-86
pubmed: 21291396
J Cereb Blood Flow Metab. 2013 Jan;33(1):53-8
pubmed: 22968319
J Med Chem. 2008 Jul 10;51(13):3700-12
pubmed: 18557607
J Nucl Med. 2010 Jan;51(1):1-4
pubmed: 20008995
J Nucl Med. 2007 Dec;48(12):2072-9
pubmed: 18006619
Eur J Nucl Med Mol Imaging. 2017 Feb;44(2):296-307
pubmed: 27699720
Nucl Med Biol. 2011 Jan;38(1):137-48
pubmed: 21220137
J Nucl Med. 2021 Apr;62(4):536-544
pubmed: 32859708
J Nucl Med. 2011 Jan;52(1):24-32
pubmed: 21149489
Theranostics. 2015 May 26;5(9):961-9
pubmed: 26155312
Neuroimage. 2010 Feb 15;49(4):2924-32
pubmed: 19948230
J Recept Signal Transduct Res. 2003;23(2-3):225-38
pubmed: 14626449
J Med Chem. 2008 Nov 13;51(21):6876-88
pubmed: 18834105
BMB Rep. 2020 Jan;53(1):20-27
pubmed: 31818362
Bioorg Med Chem Lett. 2003 Jan 20;13(2):201-4
pubmed: 12482423
Biochem Pharmacol. 1973 Dec 1;22(23):3099-108
pubmed: 4202581
J Med Chem. 2008 Sep 25;51(18):5798-806
pubmed: 18729350
Life Sci. 2006 Jun 13;79(3):287-94
pubmed: 16464478
Eur J Nucl Med Mol Imaging. 2019 Dec;46(13):2831-2847
pubmed: 31396666
J Cereb Blood Flow Metab. 2012 Jan;32(1):1-5
pubmed: 22008728
Naunyn Schmiedebergs Arch Pharmacol. 1985 Feb;328(4):454-60
pubmed: 2986017
Eur J Nucl Med Mol Imaging. 2008 Dec;35(12):2304-19
pubmed: 18828015