Redox Regulation of Lipid Mobilization in Adipose Tissues.
antioxidants
lipogenesis
lipolysis
oxidative stress
redox signaling
Journal
Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981
Informations de publication
Date de publication:
07 Jul 2021
07 Jul 2021
Historique:
received:
31
05
2021
revised:
30
06
2021
accepted:
01
07
2021
entrez:
6
8
2021
pubmed:
7
8
2021
medline:
7
8
2021
Statut:
epublish
Résumé
Lipid mobilization in adipose tissues, which includes lipogenesis and lipolysis, is a paramount process in regulating systemic energy metabolism. Reactive oxygen and nitrogen species (ROS and RNS) are byproducts of cellular metabolism that exert signaling functions in several cellular processes, including lipolysis and lipogenesis. During lipolysis, the adipose tissue generates ROS and RNS and thus requires a robust antioxidant response to maintain tight regulation of redox signaling. This review will discuss the production of ROS and RNS within the adipose tissue, their role in regulating lipolysis and lipogenesis, and the implications of antioxidants on lipid mobilization.
Identifiants
pubmed: 34356323
pii: antiox10071090
doi: 10.3390/antiox10071090
pmc: PMC8301038
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : U.S. Department of Agriculture
ID : 2019-67015-29443, 2021-67015-34563
Organisme : College of Veterinary Medicine Graduate Office Fellowship Fund
ID : Summer 2020
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