Dual Mechanisms of Cardiac Action Potential Prolongation by 4-Oxo-Nonenal Increasing the Risk of Arrhythmia; Late Na

4-oxo-nonenal arrhythmia heart late Na+ current lipid peroxidation

Journal

Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981

Informations de publication

Date de publication:
19 Jul 2021
Historique:
received: 22 06 2021
revised: 13 07 2021
accepted: 15 07 2021
entrez: 6 8 2021
pubmed: 7 8 2021
medline: 7 8 2021
Statut: epublish

Résumé

4-Oxo-nonenal (4-ONE) is an endogenous lipid peroxidation product that is more reactive than 4-hydroxy-nonenal (4-HNE). We previously reported the arrhythmic potential of 4-HNE by suppression of cardiac human Ether-a-go-go Related Gene (hERG) K

Identifiants

pubmed: 34356372
pii: antiox10071139
doi: 10.3390/antiox10071139
pmc: PMC8301175
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : National Research Foundation of Korea
ID : NRF-2018R1A5A2025964
Organisme : National Research Foundation of Korea
ID : NRF-2021R1A2C2007243
Organisme : National Research Foundation of Korea
ID : NRF-2019R1I1A1A01064006

Références

J Mol Cell Cardiol. 2005 Mar;38(3):475-83
pubmed: 15733907
Naunyn Schmiedebergs Arch Pharmacol. 2000 Dec;362(6):453-79
pubmed: 11138838
Redox Biol. 2019 May;23:101119
pubmed: 30833142
Nat Rev Cardiol. 2009 May;6(5):337-48
pubmed: 19377496
Circulation. 2008 Apr 15;117(15):1927-35
pubmed: 18378609
Front Physiol. 2017 Aug 23;8:616
pubmed: 28878692
JACC Clin Electrophysiol. 2018 May;4(5):569-579
pubmed: 29798782
Front Pharmacol. 2011 Nov 09;2:71
pubmed: 22084632
Redox Biol. 2013 Dec 18;2:148-55
pubmed: 24494189
Physiol Rep. 2016 Apr;4(7):
pubmed: 27081162
J Biol Chem. 2000 Sep 15;275(37):28810-5
pubmed: 10833522
Pflugers Arch. 2012 Apr;463(4):513-22
pubmed: 22234427
Toxicol Appl Pharmacol. 2010 May 15;245(1):76-82
pubmed: 20153347
Free Radic Res. 2013 Aug;47 Suppl 1:3-27
pubmed: 23767955
Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H794-H801
pubmed: 29932771
J Physiol. 1996 Dec 1;497 ( Pt 2):337-47
pubmed: 8961179
Chem Res Toxicol. 2007 Jul;20(7):1008-18
pubmed: 17550273
Chem Res Toxicol. 2003 Apr;16(4):512-23
pubmed: 12703968
Redox Biol. 2018 Oct;19:190-199
pubmed: 30172983
Cardiovasc Res. 2004 Feb 1;61(2):256-67
pubmed: 14736542
Chem Biol Interact. 2003 Feb 1;143-144:93-100
pubmed: 12604193
Channels (Austin). 2021 Dec;15(1):1-19
pubmed: 33258400
Cell Mol Life Sci. 1999 Mar;55(3):494-505
pubmed: 10228563
Gene. 2015 Dec 1;573(2):177-87
pubmed: 26361848
Chem Biol Interact. 2011 Jun 30;192(1-2):14-20
pubmed: 21238437
Pharmacol Ther. 2012 Mar;133(3):311-23
pubmed: 22133843
Antioxidants (Basel). 2016 Feb 19;5(1):
pubmed: 26907355
Chem Res Toxicol. 2000 Aug;13(8):698-702
pubmed: 10956056
J Clin Invest. 2002 Nov;110(9):1251-62
pubmed: 12417563
Am J Physiol Cell Physiol. 2011 May;300(5):C951-67
pubmed: 21178108
Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9355-60
pubmed: 18591664
Am J Physiol Heart Circ Physiol. 2012 Feb 1;302(3):H782-9
pubmed: 22101522
J Physiol. 2008 Jul 15;586(14):3447-59
pubmed: 18499726
Clin Pharmacol Ther. 2019 Feb;105(2):466-475
pubmed: 30151907
Curr Drug Metab. 2006 Dec;7(8):853-72
pubmed: 17168687
Nutr Metab Cardiovasc Dis. 2005 Aug;15(4):316-28
pubmed: 16054557
Channels (Austin). 2017 Nov 2;11(6):517-533
pubmed: 28837385
Chem Res Toxicol. 2002 Nov;15(11):1445-50
pubmed: 12437335
Eur Heart J. 2011 Apr;32(8):1025-38
pubmed: 20705694
Int J Cardiol. 2015;187:66-74
pubmed: 25828315
J Med Genet. 2004 May;41(5):e66
pubmed: 15121794
Toxicol Appl Pharmacol. 2010 Jan 15;242(2):191-8
pubmed: 19837106

Auteurs

Seong-Woo Choi (SW)

Department of Physiology, Dongguk University College of Medicine, Gyeongju 38066, Korea.

Ming-Zhe Yin (MZ)

Department of Physiology, Seoul National University College of Medicine, Seoul 03080, Korea.
Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310058, China.

Na-Kyeong Park (NK)

Department of Physiology, Seoul National University College of Medicine, Seoul 03080, Korea.

Joo-Han Woo (JH)

Department of Physiology, Dongguk University College of Medicine, Gyeongju 38066, Korea.

Sung-Joon Kim (SJ)

Department of Physiology, Seoul National University College of Medicine, Seoul 03080, Korea.

Classifications MeSH